HIV-1 elite controllers present a high frequency of activated regulatory T and Th17 cells

HIV-1 infection is characterized by generalized deregulation of the immune system, resulting in increased chronic immune activation. However, some individuals called HIV controllers (HICs) present spontaneous control of viral replication and have a more preserved immune system. Among HICs, discordan...

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Veröffentlicht in:	PloS one 2020-02, Vol.15 (2), p.e0228745-e0228745
Hauptverfasser:	Caetano, Diogo G, de Paula, Hury H S, Bello, Gonzalo, Hoagland, Brenda, Villela, Larissa M, Grinsztejn, Beatriz, Veloso, Valdilea G, Morgado, Mariza G, Guimarães, Monick L, Côrtes, Fernanda H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Antiretroviral drugs Biology and Life Sciences CD4 antigen CD8 antigen Cell activation Cell cycle Cell differentiation Comparative analysis Controllers Deregulation Female Health aspects Helper cells HIV HIV Infections - immunology HIV-1 - physiology Human immunodeficiency virus Humans Immune system Immunological memory Infection Infections Laboratories Levels Lymphocyte Activation Lymphocyte Count Lymphocytes Lymphocytes T Male Medicine and Health Sciences Memory cells Middle Aged Mucosa Periodical publishing Plasma Stem cells T cells T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology Th17 Cells - cytology Th17 Cells - immunology Venture capital Venture capital companies Virus replication
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