iCARE: An R package to build, validate and apply absolute risk models

This report describes an R package, called the Individualized Coherent Absolute Risk Estimator (iCARE) tool, that allows researchers to build and evaluate models for absolute risk and apply them to estimate an individual's risk of developing disease during a specified time interval based on a s...

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Veröffentlicht in:	PloS one 2020-02, Vol.15 (2), p.e0228198-e0228198
Hauptverfasser:	Pal Choudhury, Parichoy, Maas, Paige, Wilcox, Amber, Wheeler, William, Brook, Mark, Check, David, Garcia-Closas, Montserrat, Chatterjee, Nilanjan
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Area Under Curve Biology and Life Sciences Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Calibration Cancer Chromosomes Cohort analysis Computer programs Disease Diseases Epidemiology Estimates Female Gene frequency Genetic polymorphisms Genetics Genome-Wide Association Study - methods Health risk assessment Health risks Humans Medical research Medicine and Health Sciences Mortality Nucleotides Physical Sciences Polymorphism, Single Nucleotide Public health Research and Analysis Methods Researchers Risk analysis Risk assessment Risk Factors ROC Curve Single nucleotide polymorphisms Single-nucleotide polymorphism Software Software upgrading Time
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