Spatial transmission risk during the 2007-2010 Q fever epidemic in The Netherlands: Analysis of the farm-to-farm and farm-to-resident transmission
Between 2007 and 2010 a Q fever epidemic in Dutch dairy goat farms caused a large Q fever outbreak in human residents in the southern part of the Netherlands. Here we characterize the transmission of Coxiella burnetii, the aetiological agent of Q fever, between infected and susceptible dairy goat fa...
Gespeichert in:
| Veröffentlicht in: | PloS one 2020-02, Vol.15 (2), p.e0227491-e0227491 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0227491 |
|---|---|
| container_issue | 2 |
| container_start_page | e0227491 |
| container_title | PloS one |
| container_volume | 15 |
| creator | Koeijer, Aline A de Hagenaars, Thomas J Leuken, Jeroen P G van Swart, Arno N Boender, Gert Jan |
| description | Between 2007 and 2010 a Q fever epidemic in Dutch dairy goat farms caused a large Q fever outbreak in human residents in the southern part of the Netherlands. Here we characterize the transmission of Coxiella burnetii, the aetiological agent of Q fever, between infected and susceptible dairy goat farms by estimating a spatial transmission kernel. In addition, we characterize the zoonotic transmission of C. burnetii by estimating the spatial kernel for transmission from infected farms to neighbouring residents. Whereas the range of between-farm transmission is comparable to the scale of the Netherlands, likely due to long-range between-farm contacts such as animal transport, the transmission risk from farms to humans is more localized, although still extending to 10 km and beyond. Within a range of about 10 km, the transmission risk from an infected goat farm to a single resident is of the same order of magnitude as the farm-to-farm transmission risk per animal in a receiving farm. We illustrate how, based on the estimated kernels, spatial patterns of transmission risks between farms and from farms to residents can be calculated and visualized by means of risk maps, offering further insight relevant to policy making in a one-health context. |
| doi_str_mv | 10.1371/journal.pone.0227491 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2350890247</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A613180246</galeid><doaj_id>oai_doaj_org_article_346b1cccae9c4388b318f29c2165bbc9</doaj_id><sourcerecordid>A613180246</sourcerecordid><originalsourceid>FETCH-LOGICAL-c622t-f191e68c0b3de14670ce1562bdf4cd7de304c67bd4dae0a8556ccbab80466a4e3</originalsourceid><addsrcrecordid>eNqNk11v0zAUhiMEYmPwDxBYQkJwkeKP1El2gVRNfFSamGCDW8txTlqPNC62M7G_wS_mtM2qBu2C5MLRyfO-5_jYJ0meMzphImfvrl3vO91O1q6DCeU8z0r2IDlmpeCp5FQ8PPg-Sp6EcE3pVBRSPk6OBKcsz3N2nPy5XOtodUui111Y2RCs64i34Sepe2-7BYlLIJzSPEUNJV9JAzfgCaxtDStriO3IFRJfADnf6q4Op2SGdd0GG4hrtvJG-1UaXbpZCSL7gIeANl0cZX-aPGp0G-DZsJ4k3z9-uDr7nJ5ffJqfzc5TIzmPacNKBrIwtBI1sEzm1ACbSl7VTWbqvAZBMyPzqs5qDVQX06k0ptJVQTMpdQbiJHm58123LqihnUFxMaVFSXmWIzHfEbXT12rt7Ur7W-W0VduA8wulfbSmBSUyWTFjjIbSZKIoKsGKhpeGMzmtKlOi1_shW1-toDa4a6_bken4T2eXauFulCzxYQUavBkMvPvVQ4gK-2WgxZ6D67d1s6zAOiiir_5B79_dQC00bsB2jcO8ZmOqZpJh_UhJpCb3UPhujx_vXmMxPhK8HQmQifA7LnQfgppffvt_9uLHmH19wC5Bt3EZXNtHvDJhDGY70HgXgodm32RG1WZ07rqhNqOjhtFB2YvDA9qL7mZF_AWAGRRp</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2350890247</pqid></control><display><type>article</type><title>Spatial transmission risk during the 2007-2010 Q fever epidemic in The Netherlands: Analysis of the farm-to-farm and farm-to-resident transmission</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Koeijer, Aline A de ; Hagenaars, Thomas J ; Leuken, Jeroen P G van ; Swart, Arno N ; Boender, Gert Jan</creator><contributor>Gregori, Luisa</contributor><creatorcontrib>Koeijer, Aline A de ; Hagenaars, Thomas J ; Leuken, Jeroen P G van ; Swart, Arno N ; Boender, Gert Jan ; Gregori, Luisa</creatorcontrib><description>Between 2007 and 2010 a Q fever epidemic in Dutch dairy goat farms caused a large Q fever outbreak in human residents in the southern part of the Netherlands. Here we characterize the transmission of Coxiella burnetii, the aetiological agent of Q fever, between infected and susceptible dairy goat farms by estimating a spatial transmission kernel. In addition, we characterize the zoonotic transmission of C. burnetii by estimating the spatial kernel for transmission from infected farms to neighbouring residents. Whereas the range of between-farm transmission is comparable to the scale of the Netherlands, likely due to long-range between-farm contacts such as animal transport, the transmission risk from farms to humans is more localized, although still extending to 10 km and beyond. Within a range of about 10 km, the transmission risk from an infected goat farm to a single resident is of the same order of magnitude as the farm-to-farm transmission risk per animal in a receiving farm. We illustrate how, based on the estimated kernels, spatial patterns of transmission risks between farms and from farms to residents can be calculated and visualized by means of risk maps, offering further insight relevant to policy making in a one-health context.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0227491</identifier><identifier>PMID: 32017771</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abortion ; Animals ; Bacteriology ; Basic Reproduction Number ; Biology and Life Sciences ; Dairy farms ; Datasets ; Disease control ; Disease transmission ; Epidemics ; Epidemiology ; Estimation ; Farms ; Fever ; Geography ; Goat Diseases - epidemiology ; Goats ; Goats - microbiology ; Health risk assessment ; Health risks ; Health services ; Humans ; Infectious diseases ; Kernels ; Livestock farms ; Medicine and Health Sciences ; Netherlands ; Netherlands - epidemiology ; People and places ; Population Density ; Public health ; Q fever ; Q Fever - epidemiology ; Q Fever - transmission ; Risk ; Risk Factors ; Zoonoses</subject><ispartof>PloS one, 2020-02, Vol.15 (2), p.e0227491-e0227491</ispartof><rights>COPYRIGHT 2020 Public Library of Science</rights><rights>2020 Koeijer et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 Koeijer et al 2020 Koeijer et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c622t-f191e68c0b3de14670ce1562bdf4cd7de304c67bd4dae0a8556ccbab80466a4e3</citedby><cites>FETCH-LOGICAL-c622t-f191e68c0b3de14670ce1562bdf4cd7de304c67bd4dae0a8556ccbab80466a4e3</cites><orcidid>0000-0002-8780-2481</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999918/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999918/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2929,23868,27926,27927,53793,53795</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32017771$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Gregori, Luisa</contributor><creatorcontrib>Koeijer, Aline A de</creatorcontrib><creatorcontrib>Hagenaars, Thomas J</creatorcontrib><creatorcontrib>Leuken, Jeroen P G van</creatorcontrib><creatorcontrib>Swart, Arno N</creatorcontrib><creatorcontrib>Boender, Gert Jan</creatorcontrib><title>Spatial transmission risk during the 2007-2010 Q fever epidemic in The Netherlands: Analysis of the farm-to-farm and farm-to-resident transmission</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Between 2007 and 2010 a Q fever epidemic in Dutch dairy goat farms caused a large Q fever outbreak in human residents in the southern part of the Netherlands. Here we characterize the transmission of Coxiella burnetii, the aetiological agent of Q fever, between infected and susceptible dairy goat farms by estimating a spatial transmission kernel. In addition, we characterize the zoonotic transmission of C. burnetii by estimating the spatial kernel for transmission from infected farms to neighbouring residents. Whereas the range of between-farm transmission is comparable to the scale of the Netherlands, likely due to long-range between-farm contacts such as animal transport, the transmission risk from farms to humans is more localized, although still extending to 10 km and beyond. Within a range of about 10 km, the transmission risk from an infected goat farm to a single resident is of the same order of magnitude as the farm-to-farm transmission risk per animal in a receiving farm. We illustrate how, based on the estimated kernels, spatial patterns of transmission risks between farms and from farms to residents can be calculated and visualized by means of risk maps, offering further insight relevant to policy making in a one-health context.</description><subject>Abortion</subject><subject>Animals</subject><subject>Bacteriology</subject><subject>Basic Reproduction Number</subject><subject>Biology and Life Sciences</subject><subject>Dairy farms</subject><subject>Datasets</subject><subject>Disease control</subject><subject>Disease transmission</subject><subject>Epidemics</subject><subject>Epidemiology</subject><subject>Estimation</subject><subject>Farms</subject><subject>Fever</subject><subject>Geography</subject><subject>Goat Diseases - epidemiology</subject><subject>Goats</subject><subject>Goats - microbiology</subject><subject>Health risk assessment</subject><subject>Health risks</subject><subject>Health services</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Kernels</subject><subject>Livestock farms</subject><subject>Medicine and Health Sciences</subject><subject>Netherlands</subject><subject>Netherlands - epidemiology</subject><subject>People and places</subject><subject>Population Density</subject><subject>Public health</subject><subject>Q fever</subject><subject>Q Fever - epidemiology</subject><subject>Q Fever - transmission</subject><subject>Risk</subject><subject>Risk Factors</subject><subject>Zoonoses</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk11v0zAUhiMEYmPwDxBYQkJwkeKP1El2gVRNfFSamGCDW8txTlqPNC62M7G_wS_mtM2qBu2C5MLRyfO-5_jYJ0meMzphImfvrl3vO91O1q6DCeU8z0r2IDlmpeCp5FQ8PPg-Sp6EcE3pVBRSPk6OBKcsz3N2nPy5XOtodUui111Y2RCs64i34Sepe2-7BYlLIJzSPEUNJV9JAzfgCaxtDStriO3IFRJfADnf6q4Op2SGdd0GG4hrtvJG-1UaXbpZCSL7gIeANl0cZX-aPGp0G-DZsJ4k3z9-uDr7nJ5ffJqfzc5TIzmPacNKBrIwtBI1sEzm1ACbSl7VTWbqvAZBMyPzqs5qDVQX06k0ptJVQTMpdQbiJHm58123LqihnUFxMaVFSXmWIzHfEbXT12rt7Ur7W-W0VduA8wulfbSmBSUyWTFjjIbSZKIoKsGKhpeGMzmtKlOi1_shW1-toDa4a6_bken4T2eXauFulCzxYQUavBkMvPvVQ4gK-2WgxZ6D67d1s6zAOiiir_5B79_dQC00bsB2jcO8ZmOqZpJh_UhJpCb3UPhujx_vXmMxPhK8HQmQifA7LnQfgppffvt_9uLHmH19wC5Bt3EZXNtHvDJhDGY70HgXgodm32RG1WZ07rqhNqOjhtFB2YvDA9qL7mZF_AWAGRRp</recordid><startdate>20200204</startdate><enddate>20200204</enddate><creator>Koeijer, Aline A de</creator><creator>Hagenaars, Thomas J</creator><creator>Leuken, Jeroen P G van</creator><creator>Swart, Arno N</creator><creator>Boender, Gert Jan</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-8780-2481</orcidid></search><sort><creationdate>20200204</creationdate><title>Spatial transmission risk during the 2007-2010 Q fever epidemic in The Netherlands: Analysis of the farm-to-farm and farm-to-resident transmission</title><author>Koeijer, Aline A de ; Hagenaars, Thomas J ; Leuken, Jeroen P G van ; Swart, Arno N ; Boender, Gert Jan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c622t-f191e68c0b3de14670ce1562bdf4cd7de304c67bd4dae0a8556ccbab80466a4e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Abortion</topic><topic>Animals</topic><topic>Bacteriology</topic><topic>Basic Reproduction Number</topic><topic>Biology and Life Sciences</topic><topic>Dairy farms</topic><topic>Datasets</topic><topic>Disease control</topic><topic>Disease transmission</topic><topic>Epidemics</topic><topic>Epidemiology</topic><topic>Estimation</topic><topic>Farms</topic><topic>Fever</topic><topic>Geography</topic><topic>Goat Diseases - epidemiology</topic><topic>Goats</topic><topic>Goats - microbiology</topic><topic>Health risk assessment</topic><topic>Health risks</topic><topic>Health services</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Kernels</topic><topic>Livestock farms</topic><topic>Medicine and Health Sciences</topic><topic>Netherlands</topic><topic>Netherlands - epidemiology</topic><topic>People and places</topic><topic>Population Density</topic><topic>Public health</topic><topic>Q fever</topic><topic>Q Fever - epidemiology</topic><topic>Q Fever - transmission</topic><topic>Risk</topic><topic>Risk Factors</topic><topic>Zoonoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Koeijer, Aline A de</creatorcontrib><creatorcontrib>Hagenaars, Thomas J</creatorcontrib><creatorcontrib>Leuken, Jeroen P G van</creatorcontrib><creatorcontrib>Swart, Arno N</creatorcontrib><creatorcontrib>Boender, Gert Jan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Koeijer, Aline A de</au><au>Hagenaars, Thomas J</au><au>Leuken, Jeroen P G van</au><au>Swart, Arno N</au><au>Boender, Gert Jan</au><au>Gregori, Luisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Spatial transmission risk during the 2007-2010 Q fever epidemic in The Netherlands: Analysis of the farm-to-farm and farm-to-resident transmission</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2020-02-04</date><risdate>2020</risdate><volume>15</volume><issue>2</issue><spage>e0227491</spage><epage>e0227491</epage><pages>e0227491-e0227491</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Between 2007 and 2010 a Q fever epidemic in Dutch dairy goat farms caused a large Q fever outbreak in human residents in the southern part of the Netherlands. Here we characterize the transmission of Coxiella burnetii, the aetiological agent of Q fever, between infected and susceptible dairy goat farms by estimating a spatial transmission kernel. In addition, we characterize the zoonotic transmission of C. burnetii by estimating the spatial kernel for transmission from infected farms to neighbouring residents. Whereas the range of between-farm transmission is comparable to the scale of the Netherlands, likely due to long-range between-farm contacts such as animal transport, the transmission risk from farms to humans is more localized, although still extending to 10 km and beyond. Within a range of about 10 km, the transmission risk from an infected goat farm to a single resident is of the same order of magnitude as the farm-to-farm transmission risk per animal in a receiving farm. We illustrate how, based on the estimated kernels, spatial patterns of transmission risks between farms and from farms to residents can be calculated and visualized by means of risk maps, offering further insight relevant to policy making in a one-health context.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>32017771</pmid><doi>10.1371/journal.pone.0227491</doi><tpages>e0227491</tpages><orcidid>https://orcid.org/0000-0002-8780-2481</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2020-02, Vol.15 (2), p.e0227491-e0227491 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2350890247 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Abortion Animals Bacteriology Basic Reproduction Number Biology and Life Sciences Dairy farms Datasets Disease control Disease transmission Epidemics Epidemiology Estimation Farms Fever Geography Goat Diseases - epidemiology Goats Goats - microbiology Health risk assessment Health risks Health services Humans Infectious diseases Kernels Livestock farms Medicine and Health Sciences Netherlands Netherlands - epidemiology People and places Population Density Public health Q fever Q Fever - epidemiology Q Fever - transmission Risk Risk Factors Zoonoses |
| title | Spatial transmission risk during the 2007-2010 Q fever epidemic in The Netherlands: Analysis of the farm-to-farm and farm-to-resident transmission |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T00%3A02%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Spatial%20transmission%20risk%20during%20the%202007-2010%20Q%20fever%20epidemic%20in%20The%20Netherlands:%20Analysis%20of%20the%20farm-to-farm%20and%20farm-to-resident%20transmission&rft.jtitle=PloS%20one&rft.au=Koeijer,%20Aline%20A%20de&rft.date=2020-02-04&rft.volume=15&rft.issue=2&rft.spage=e0227491&rft.epage=e0227491&rft.pages=e0227491-e0227491&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0227491&rft_dat=%3Cgale_plos_%3EA613180246%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2350890247&rft_id=info:pmid/32017771&rft_galeid=A613180246&rft_doaj_id=oai_doaj_org_article_346b1cccae9c4388b318f29c2165bbc9&rfr_iscdi=true |