Aseptic bone-flap resorption after cranioplasty - incidence and risk factors
One of the common complications occurring after cranioplasty (CP) is aseptic bone-flap resorption (ABFR). Reoperation necessary because of the development of ABFR can lead to unfavorable complications during subsequent surgery using a synthetic skull implant, and also necessarily leads to higher cos...
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| description | One of the common complications occurring after cranioplasty (CP) is aseptic bone-flap resorption (ABFR). Reoperation necessary because of the development of ABFR can lead to unfavorable complications during subsequent surgery using a synthetic skull implant, and also necessarily leads to higher costs. The aim of this study is to identify prognostic factors that may help to predict the development of ABFR.
In this study, 303 CP surgeries performed between 2002 and 2017 were examined retrospectively to identify factors predicting the occurrence of ABFR. A number of these factors (e.g., time lapse between decompressive craniectomy (DC) and CP, bone-flap size, specific laboratory signs, and the reason for the original DC) were analyzed as possibly influencing the risk of developing ABFR.
ABFR of an autologous bone flap that subsequently required a CP with synthetic skull implants occurred in 10 of 303 patients (3.0%). CP timing and patients' Karnofsky Performance Scores (KPS) (p = 0.008; p = 0.012) were identified as significant factors with an impact on the development of ABRF. Age did not reveal a significant value, but statistical analysis shows a clear trend. The younger the age, the more likely it was that an ABFR would develop.
The risk of ABFR lessens the longer the period of time elapsed between DC and CP. Age does not reveal a significant value, but statistical analysis shows that there is a clear trend. |
| doi_str_mv | 10.1371/journal.pone.0228009 |
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In this study, 303 CP surgeries performed between 2002 and 2017 were examined retrospectively to identify factors predicting the occurrence of ABFR. A number of these factors (e.g., time lapse between decompressive craniectomy (DC) and CP, bone-flap size, specific laboratory signs, and the reason for the original DC) were analyzed as possibly influencing the risk of developing ABFR.
ABFR of an autologous bone flap that subsequently required a CP with synthetic skull implants occurred in 10 of 303 patients (3.0%). CP timing and patients' Karnofsky Performance Scores (KPS) (p = 0.008; p = 0.012) were identified as significant factors with an impact on the development of ABRF. Age did not reveal a significant value, but statistical analysis shows a clear trend. The younger the age, the more likely it was that an ABFR would develop.
The risk of ABFR lessens the longer the period of time elapsed between DC and CP. Age does not reveal a significant value, but statistical analysis shows that there is a clear trend.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0228009</identifier><identifier>PMID: 31999739</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adolescent ; Adult ; Age ; Aged ; Aged, 80 and over ; Biology and Life Sciences ; Bone implants ; Bone resorption ; Bone Resorption - diagnostic imaging ; Bone Resorption - epidemiology ; Bone Resorption - etiology ; Brain research ; Child ; Child, Preschool ; Complications ; Complications and side effects ; Decompression, Surgical ; Engineering and Technology ; Female ; Health aspects ; Hemorrhage ; Humans ; Incidence ; Infections ; Laboratories ; Male ; Medicine and Health Sciences ; Middle Aged ; Neurosurgery ; Patients ; Physical Sciences ; Plastic surgery ; Reason ; Research and Analysis Methods ; Risk analysis ; Risk Factors ; Skull ; Statistical analysis ; Statistics ; Stroke ; Studies ; Surgery ; Surgical Flaps ; Surgical implants ; Synthetic products ; Time ; Titanium ; Tomography ; Tomography, X-Ray Computed ; Transplants & implants ; Traumatic brain injury ; Young Adult</subject><ispartof>PloS one, 2020-01, Vol.15 (1), p.e0228009-e0228009</ispartof><rights>COPYRIGHT 2020 Public Library of Science</rights><rights>2020 Rashidi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 Rashidi et al 2020 Rashidi et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-5daf0c8488db4583fe9a6f37d75d65bb2c1cc5392b2b8c210136ed607e02f00c3</citedby><cites>FETCH-LOGICAL-c692t-5daf0c8488db4583fe9a6f37d75d65bb2c1cc5392b2b8c210136ed607e02f00c3</cites><orcidid>0000-0002-9947-9095</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992164/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992164/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2095,2914,23846,27903,27904,53769,53771,79346,79347</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31999739$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Cray, JJ</contributor><creatorcontrib>Rashidi, Ali</creatorcontrib><creatorcontrib>Sandalcioglu, I Erol</creatorcontrib><creatorcontrib>Luchtmann, Michael</creatorcontrib><title>Aseptic bone-flap resorption after cranioplasty - incidence and risk factors</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>One of the common complications occurring after cranioplasty (CP) is aseptic bone-flap resorption (ABFR). Reoperation necessary because of the development of ABFR can lead to unfavorable complications during subsequent surgery using a synthetic skull implant, and also necessarily leads to higher costs. The aim of this study is to identify prognostic factors that may help to predict the development of ABFR.
In this study, 303 CP surgeries performed between 2002 and 2017 were examined retrospectively to identify factors predicting the occurrence of ABFR. A number of these factors (e.g., time lapse between decompressive craniectomy (DC) and CP, bone-flap size, specific laboratory signs, and the reason for the original DC) were analyzed as possibly influencing the risk of developing ABFR.
ABFR of an autologous bone flap that subsequently required a CP with synthetic skull implants occurred in 10 of 303 patients (3.0%). CP timing and patients' Karnofsky Performance Scores (KPS) (p = 0.008; p = 0.012) were identified as significant factors with an impact on the development of ABRF. Age did not reveal a significant value, but statistical analysis shows a clear trend. The younger the age, the more likely it was that an ABFR would develop.
The risk of ABFR lessens the longer the period of time elapsed between DC and CP. Age does not reveal a significant value, but statistical analysis shows that there is a clear trend.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biology and Life Sciences</subject><subject>Bone implants</subject><subject>Bone resorption</subject><subject>Bone Resorption - diagnostic imaging</subject><subject>Bone Resorption - epidemiology</subject><subject>Bone Resorption - etiology</subject><subject>Brain research</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Complications</subject><subject>Complications and side effects</subject><subject>Decompression, Surgical</subject><subject>Engineering and Technology</subject><subject>Female</subject><subject>Health 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bone-flap resorption after cranioplasty - incidence and risk factors</title><author>Rashidi, Ali ; Sandalcioglu, I Erol ; Luchtmann, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-5daf0c8488db4583fe9a6f37d75d65bb2c1cc5392b2b8c210136ed607e02f00c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biology and Life Sciences</topic><topic>Bone implants</topic><topic>Bone resorption</topic><topic>Bone Resorption - diagnostic imaging</topic><topic>Bone Resorption - epidemiology</topic><topic>Bone Resorption - etiology</topic><topic>Brain research</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Complications</topic><topic>Complications and side effects</topic><topic>Decompression, Surgical</topic><topic>Engineering and 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Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rashidi, Ali</au><au>Sandalcioglu, I Erol</au><au>Luchtmann, Michael</au><au>Cray, JJ</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aseptic bone-flap resorption after cranioplasty - incidence and risk factors</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2020-01-30</date><risdate>2020</risdate><volume>15</volume><issue>1</issue><spage>e0228009</spage><epage>e0228009</epage><pages>e0228009-e0228009</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>One of the common complications occurring after cranioplasty (CP) is aseptic bone-flap resorption (ABFR). Reoperation necessary because of the development of ABFR can lead to unfavorable complications during subsequent surgery using a synthetic skull implant, and also necessarily leads to higher costs. The aim of this study is to identify prognostic factors that may help to predict the development of ABFR.
In this study, 303 CP surgeries performed between 2002 and 2017 were examined retrospectively to identify factors predicting the occurrence of ABFR. A number of these factors (e.g., time lapse between decompressive craniectomy (DC) and CP, bone-flap size, specific laboratory signs, and the reason for the original DC) were analyzed as possibly influencing the risk of developing ABFR.
ABFR of an autologous bone flap that subsequently required a CP with synthetic skull implants occurred in 10 of 303 patients (3.0%). CP timing and patients' Karnofsky Performance Scores (KPS) (p = 0.008; p = 0.012) were identified as significant factors with an impact on the development of ABRF. Age did not reveal a significant value, but statistical analysis shows a clear trend. The younger the age, the more likely it was that an ABFR would develop.
The risk of ABFR lessens the longer the period of time elapsed between DC and CP. Age does not reveal a significant value, but statistical analysis shows that there is a clear trend.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>31999739</pmid><doi>10.1371/journal.pone.0228009</doi><orcidid>https://orcid.org/0000-0002-9947-9095</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Age Aged Aged, 80 and over Biology and Life Sciences Bone implants Bone resorption Bone Resorption - diagnostic imaging Bone Resorption - epidemiology Bone Resorption - etiology Brain research Child Child, Preschool Complications Complications and side effects Decompression, Surgical Engineering and Technology Female Health aspects Hemorrhage Humans Incidence Infections Laboratories Male Medicine and Health Sciences Middle Aged Neurosurgery Patients Physical Sciences Plastic surgery Reason Research and Analysis Methods Risk analysis Risk Factors Skull Statistical analysis Statistics Stroke Studies Surgery Surgical Flaps Surgical implants Synthetic products Time Titanium Tomography Tomography, X-Ray Computed Transplants & implants Traumatic brain injury Young Adult |
| title | Aseptic bone-flap resorption after cranioplasty - incidence and risk factors |
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