The interoceptive hippocampus: Mouse brain endocrine receptor expression highlights a dentate gyrus (DG)-cornu ammonis (CA) challenge-sufficiency axis

The primeval function of the mammalian hippocampus (HPC) remains uncertain. Implicated in learning and memory, spatial navigation, and neuropsychological disorders, evolutionary theory suggests that the HPC evolved from a primeval chemosensory epithelium. Deficits in sensing of internal body status...

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Veröffentlicht in:	PloS one 2020-01, Vol.15 (1), p.e0227575-e0227575
Hauptverfasser:	Lathe, Richard, Singadia, Sheena, Jordan, Crispin, Riedel, Gernot
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Behavior Biology and Life Sciences Brain Chemoreception Dentate gyrus Dentate Gyrus - metabolism Endocrine System - cytology Endocrine System - metabolism Endocrine System - physiology Epithelium Estrogen Estrogens Gene expression Gene Expression Regulation Hippocampus Hippocampus - cytology Hippocampus - metabolism Hippocampus - physiology Humans Kinases Lactose Ligands Medicine and Health Sciences Memory Mice Navigation Navigation behavior Neurogenesis Neurosciences Physiology Potentiation Receptor mechanisms Receptors Receptors, Cell Surface - metabolism Signaling Spatial discrimination learning Spatial memory Synaptic Potentials Vertebrates
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