Use of serum KL-6 level for detecting patients with restrictive allograft syndrome after lung transplantation

KL-6 is an antigen produced mainly by damaged type II pneumocytes that is involved in interstitial lung disease. Chronic lung allograft dysfunction (CLAD) after lung transplantation (LT) is a major concern for LT clinicians, especially in patients with restrictive allograft syndrome (RAS). We invest...

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Veröffentlicht in:	PloS one 2020-01, Vol.15 (1), p.e0226488-e0226488
Hauptverfasser:	Berastegui, Cristina, Gómez-Ollés, Susana, Mendoza-Valderrey, Alberto, Pereira-Veiga, Thais, Culebras, Mario, Monforte, Victor, Saez, Berta, López-Meseguer, Manuel, Sintes-Permanyer, Helena, Ruiz de Miguel, Victoria, Bravo, Carlos, Sacanell, Judit, Ramon, María-Antonia, Romero, Laura, Deu, María, Román, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alveoli Antigens Area Under Curve Biology and Life Sciences Biomarkers Biomarkers - blood Bronchiolitis obliterans Bronchiolitis Obliterans - diagnosis Bronchiolitis Obliterans - etiology Bronchoalveolar Lavage Fluid - chemistry Bronchopneumonia Bronchus Clinical trials Female Genotype & phenotype Humans Levels Lung diseases Lung Diseases - therapy Lung transplantation Lung Transplantation - adverse effects Male Medicine and Health Sciences Middle Aged Mucin-1 - analysis Mucin-1 - blood Phenotype Phenotypes Physical Sciences Physiology Pneumocytes Population Primary Graft Dysfunction - diagnosis Primary Graft Dysfunction - etiology Research and Analysis Methods ROC Curve Sensitivity and Specificity Studies Transplantation Transplantation, Homologous Vital Capacity Wound healing Xenografts Young Adult
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