Use of Nanotrap particles for the capture and enrichment of Zika, chikungunya and dengue viruses in urine

Nanotrap® (NT) particles are hydrogel microspheres developed for target analyte separation and discovery applications. NT particles consist of cross-linked N-isopropylacrylamide (NIPAm) copolymers that are functionalized with a variety of chemical affinity baits to enable broad-spectrum collection a...

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Veröffentlicht in:	PloS one 2020-01, Vol.15 (1), p.e0227058-e0227058
Hauptverfasser:	Lin, Shih-Chao, Carey, Brian D, Callahan, Victoria, Lee, Ji-Hyun, Bracci, Nicole, Patnaik, Anurag, Smith, Amy K, Narayanan, Aarthi, Lepene, Benjamin, Kehn-Hall, Kylene
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Acrylic acid Affinity Arbovirus Infections - diagnosis Arbovirus Infections - urine Arbovirus Infections - virology Baits Biology Biology and life sciences Chikungunya virus Chikungunya virus - genetics Chikungunya virus - isolation & purification Chikungunya virus - pathogenicity Coccidioidomycosis Coloring Agents - chemistry Copolymers Crosslinking Dengue Dengue fever Dengue virus Dengue Virus - genetics Dengue Virus - isolation & purification Dengue Virus - pathogenicity Encephalitis Enrichment Equine encephalomyelitis Experiments Humans Hydrogels Hydrogels - chemistry Infections Infectious diseases Infectivity Isopropylacrylamide Medicine and Health Sciences Methods Microspheres Molecular Diagnostic Techniques - methods Nanoparticles - chemistry Nanoparticles - metabolism Nucleic acids Organic chemistry Pathogenic microorganisms Pathogens Physical Sciences Polymerase Chain Reaction - methods Protein Binding Proteins Rift Valley fever Saliva Saliva - virology Technology Technology application Urine Urine - virology Vector-borne diseases Venezuelan equine encephalitis Viral diseases Viral Envelope Proteins - chemistry Viral Envelope Proteins - metabolism Viruses Zika virus Zika Virus - genetics Zika Virus - isolation & purification Zika Virus - pathogenicity
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