Impact of the change in the antitubercular regimen from three to four drugs on cure and frequency of adverse reactions in tuberculosis patients from Brazil: A retrospective cohort study

The Ministry of Health in Brazil included ethambutol in the intensive phase of sensible tuberculosis (TB) treatment in March 2010, due to the increasing drug resistance, and implemented the fixed dose combination in the TB treatment guidelines. A retrospective cohort study was performed to determine...

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Veröffentlicht in:	PloS one 2019-12, Vol.14 (12), p.e0227101
Hauptverfasser:	Arriaga, María B, Torres, Ninfa M C, Araujo, Nelia C N, Caldas, Simone C C, Andrade, Bruno B, Netto, Eduardo M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Antibiotics Antitubercular agents Antitubercular Agents - administration & dosage Antitubercular Agents - adverse effects Antitubercular Agents - therapeutic use Biology and Life Sciences Brazil - epidemiology Cohort analysis Confidence intervals Diabetes mellitus Drinking (Alcoholic beverages) Drug dosages Drug resistance Drug therapy Drug traffic Drug-Related Side Effects and Adverse Reactions - drug therapy Drug-Related Side Effects and Adverse Reactions - etiology Drugs Elderly patients Ethambutol Ethics Female Health Health aspects Humans Incidence Laboratories Male Medical diagnosis Medicine and Health Sciences Middle Aged Patients People and places Regression analysis Retrospective Studies Side effects Statistical analysis Studies Treatment Outcome Tuberculosis Tuberculosis - drug therapy Young Adult
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