STK-12 acts as a transcriptional brake to control the expression of cellulase-encoding genes in Neurospora crassa

Cellulolytic fungi have evolved a complex regulatory network to maintain the precise balance of nutrients required for growth and hydrolytic enzyme production. When fungi are exposed to cellulose, the transcript levels of cellulase genes rapidly increase and then decline. However, the mechanisms und...

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Veröffentlicht in:	PLoS genetics 2019-11, Vol.15 (11), p.e1008510-e1008510
Hauptverfasser:	Lin, Liangcai, Wang, Shanshan, Li, Xiaolin, He, Qun, Benz, J Philipp, Tian, Chaoguang
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology and Life Sciences Biotechnology Carbon Cellulase Cellulase - genetics Cellulolytic fungi Cellulose Cellulose - genetics Clonal deletion Criminal investigation Enzymes Fermentation Funding Fungal Proteins - genetics Fungi Gene expression Gene Expression Regulation, Fungal - genetics Genetic aspects Genetic research Kinases Laboratories Mechanistic Target of Rapamycin Complex 1 - genetics Metabolism Neurospora crassa Neurospora crassa - enzymology Neurospora crassa - genetics Nucleotidases Nutrients Phosphorylation Polysaccharides Protein kinase Protein kinases Proteins Repressors Research and Analysis Methods Signal transduction Transcription Transcription (Genetics) Transcription Factors - genetics
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