Comorbidity associated to Ascaris suum infection during pulmonary fibrosis exacerbates chronic lung and liver inflammation and dysfunction but not affect the parasite cycle in mice

Ascariasis is considered the most neglected tropical disease, and is a major problem for the public health system. However, idiopathic pulmonary fibrosis (IPF) is a result of chronic extracellular deposition of matrix in the pulmonary parenchyma, and thickening of the alveolar septa, which reduces a...

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Veröffentlicht in:PLoS neglected tropical diseases 2019-11, Vol.13 (11), p.e0007896-e0007896
Hauptverfasser: Oliveira, Fabrício Marcus Silva, da Paixão Matias, Pablo Hemanoel, Kraemer, Lucas, Gazzinelli-Guimarães, Ana Clara, Santos, Flaviane Vieira, Amorim, Chiara Cássia Oliveira, Nogueira, Denise Silva, Freitas, Camila Simões, Caliari, Marcelo Vidigal, Bartholomeu, Daniella Castanheira, Bueno, Lilian Lacerda, Russo, Remo Castro, Fujiwara, Ricardo Toshio
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Sprache:eng
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