The Plasmodium falciparum rhoptry bulb protein RAMA plays an essential role in rhoptry neck morphogenesis and host red blood cell invasion

The malaria parasite Plasmodium falciparum invades, replicates within and destroys red blood cells in an asexual blood stage life cycle that is responsible for clinical disease and crucial for parasite propagation. Invasive malaria merozoites possess a characteristic apical complex of secretory orga...

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Veröffentlicht in:	PLoS pathogens 2019-09, Vol.15 (9), p.e1008049-e1008049
Hauptverfasser:	Sherling, Emma S, Perrin, Abigail J, Knuepfer, Ellen, Russell, Matthew R G, Collinson, Lucy M, Miller, Louis H, Blackman, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Antigens, Protozoan - immunology Behavior Biochemistry Biology and Life Sciences Biosynthesis Blood Blood cells Crick, Francis Development and progression Disease Disruption Egress Erythrocytes Erythrocytes - parasitology Funding Health aspects Host-Parasite Interactions - physiology Host-parasite relationships Humans Kinases Laboratories Life cycles Lipids Malaria Malaria - metabolism Malaria, Falciparum - metabolism Membrane proteins Membrane Proteins - metabolism Merozoites Merozoites - metabolism Microscopy Molecular weight Morphogenesis Neck Organelles Organelles - metabolism Parasites Parasitology Plasmodium falciparum Plasmodium falciparum - metabolism Protein Transport - physiology Proteins Protozoan Proteins - metabolism Red blood cells Research and Analysis Methods Supervision Tropical diseases Vector-borne diseases
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