Dimensions of control for subthreshold oscillations and spontaneous firing in dopamine neurons

Dopaminergic neurons (DAs) of the rodent substantia nigra pars compacta (SNc) display varied electrophysiological properties in vitro. Despite this, projection patterns and functional inputs from DAs to other structures are conserved, so in vivo delivery of consistent, well-timed dopamine modulation...

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Veröffentlicht in:	PLoS computational biology 2019-09, Vol.15 (9), p.e1007375-e1007375
Hauptverfasser:	Rumbell, Timothy, Kozloski, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Algorithms Animals Biology and Life Sciences Complex variables Complexity Computational Biology Computer simulation Controllers Dopamine Dopamine receptors Dopaminergic Neurons - metabolism Dopaminergic Neurons - physiology Electrophysiology Evolutionary algorithms Intracellular Ion channels Laboratories Mathematical models Medicine and Health Sciences Models, Neurological Morphology Neurons Neurophysiology Neurosciences Oscillations Parameter robustness Physical Sciences Physiology Population Properties (attributes) Rats Regression analysis Regulators Research and Analysis Methods Robustness (mathematics) Substantia nigra Substantia Nigra - cytology Substantia Nigra - metabolism
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