A super-SILAC based proteomics analysis of diffuse large B-cell lymphoma-NOS patient samples to identify new proteins that discriminate GCB and non-GCB lymphomas

Diffuse large B-cell lymphoma-not otherwise specified (DLBCL-NOS) is a large and heterogeneous subgroup of non-Hodgkin lymphoma. DLBCL can be subdivided into germinal centre B-cell like (GCB) and activated B-cell like (ABC or non-GCB) using a gene-expression based or an immunohistochemical approach....

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Veröffentlicht in:	PloS one 2019-10, Vol.14 (10), p.e0223260-e0223260
Hauptverfasser:	van der Meeren, L E, Kluiver, J, Rutgers, B, Alsagoor, Y, Kluin, P M, van den Berg, A, Visser, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - immunology Adolescent Adult Aged Aged, 80 and over Algorithms Angiogenesis B cells B-cell lymphoma B-Lymphocytes - immunology B-Lymphocytes - pathology Biology Biology and Life Sciences Biomarkers, Tumor - genetics Biomarkers, Tumor - immunology Care and treatment Cell Line, Tumor Child Classification Cloning Cohort Studies Female Gene Expression Genetic aspects Germinal Center - immunology Germinal Center - pathology Hodgkin's disease Humans Immunohistochemistry Isotope Labeling - methods Lymphocyte Activation Lymphocytes B Lymphoma Lymphoma, Large B-Cell, Diffuse - classification Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - immunology Lymphoma, Large B-Cell, Diffuse - pathology Male Medical research Medicine and Health Sciences Middle Aged Myc protein Neoplasm Staging Non-Hodgkin's lymphoma Non-Hodgkin's lymphomas p53 Protein Pathology Physical Sciences Proteins Proteomics Proteomics - methods Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - immunology Replication Research and Analysis Methods Ribosomal protein L23 Ribosomal Proteins - genetics Ribosomal Proteins - immunology Studies Subgroups Tumor cell lines Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - immunology
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