Neutrophil elastase inhibitor purification strategy from cowpea seeds

Serine proteases and its inhibitors are involved in physiological process and its deregulation lead to various diseases like Chronic Obstructive Pulmonary Disease (COPD), pulmonary emphysema, skin diseases, atherosclerosis, coagulation diseases, cancer, inflammatory diseases, neuronal disorders and...

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Veröffentlicht in:	PloS one 2019-10, Vol.14 (10), p.e0223713-e0223713
Hauptverfasser:	Ferreira, Graziele Cristina, Duran, Adriana Feliciano Alves, da Silva, Flavia Ribeiro Santos, Bomediano, Livia de Moraes, Machado, Gabriel Capella, Sasaki, Sergio Daishi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Arteriosclerosis Atherosclerosis Beans Biological Assay Biology and Life Sciences Cattle Chemical bonds Chromatography Chronic obstructive lung disease Chronic obstructive pulmonary disease Chymotrypsin Coagulation Column chromatography Cowpeas Deregulation Dissociation Drug therapy Elastase Emphysema Enzymes Hydrolases Inflammatory diseases Ion exchange Ion exchanging Legumes Leukocyte Elastase - isolation & purification Lung diseases Mass spectrometry Mass spectroscopy Medicine and Health Sciences Neurons Neutrophils Obstructive lung disease Plant Extracts - chemistry Protease Protease inhibitors Proteases Proteinase inhibitors Proteins Research and Analysis Methods Seeds Seeds - chemistry Serine Serine proteinase Serine Proteinase Inhibitors - isolation & purification Skin Skin diseases Soybeans Spectroscopy Thrombin Trypsin Vigna - chemistry Vigna unguiculata
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