Disruption of white matter connectivity in chronic obstructive pulmonary disease

Mild cognitive impairment is a common systemic manifestation of chronic obstructive pulmonary disease (COPD). However, its pathophysiological origins are not understood. Since, cognitive function relies on efficient communication between distributed cortical and subcortical regions, we investigated...

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Veröffentlicht in:	PloS one 2019-10, Vol.14 (10), p.e0223297-e0223297
Hauptverfasser:	Spilling, Catherine A, Jones, Paul W, Dodd, James W, Barrick, Thomas R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biology and Life Sciences Brain Brain damage Brain research Care and treatment Chronic illnesses Chronic obstructive lung disease Chronic obstructive pulmonary disease Cognition Cognitive ability Cognitive disorders Cognitive Dysfunction - etiology Cognitive Dysfunction - physiopathology Cognitive Dysfunction - psychology Computer and Information Sciences Connectome Cortex Density Diffusion Tensor Imaging Disruption Female Hospitals Humans Hypertension Image Processing, Computer-Assisted Lung diseases Male Medical tests Medicine and Health Sciences Middle Aged Morbidity Mortality Networks Neural networks Neurosciences Nodes Obstructive lung disease Patients Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - diagnosis Research and Analysis Methods Respiratory Function Tests Respiratory tract diseases Risk factors Segregation Severity of Illness Index Smoking Streamlines Strength Substantia alba Substantia grisea Superior temporal gyrus Temporal gyrus White Matter - diagnostic imaging White Matter - physiology
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