Glycemic control among diabetic patients in Ethiopia: A systematic review and meta-analysis
Ethiopia recorded the highest numbers of people with diabetes in Africa. It is not uncommon for diabetic patients to have poor glycemic control leading to a number of complications. The aim of this systematic review and meta-analysis is to evaluate the level of glycemic control among diabetic patien...
Gespeichert in:
| Veröffentlicht in: | PloS one 2019-08, Vol.14 (8), p.e0221790-e0221790 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0221790 |
|---|---|
| container_issue | 8 |
| container_start_page | e0221790 |
| container_title | PloS one |
| container_volume | 14 |
| creator | Gebreyohannes, Eyob Alemayehu Netere, Adeladlew Kassie Belachew, Sewunet Admasu |
| description | Ethiopia recorded the highest numbers of people with diabetes in Africa. It is not uncommon for diabetic patients to have poor glycemic control leading to a number of complications. The aim of this systematic review and meta-analysis is to evaluate the level of glycemic control among diabetic patients in Ethiopia by combining the studies from the existing literature.
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was employed to plan and conduct this review. A comprehensive electronic-based literature search was conducted in the databases of MEDLINE, HINARI, GOOGLE SCHOLAR, and SCIENCEDIRECT. Open meta-analyst software was used to perform meta-analyses. Proportions of good glycemic control among diabetic patients was calculated. Odds ratio was also calculated to check the presence of statistically significant difference in glycemic control among patients with type 1 and type 2 diabetes.
A total of 22 studies were included in the final analysis. Meta-analysis of 16 studies showed that only one-third of patients [34.4% (95% CI: 27.9%-40.9%), p |
| doi_str_mv | 10.1371/journal.pone.0221790 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2281377149</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A597543017</galeid><doaj_id>oai_doaj_org_article_e128cf9162ef45d782c7d35f546bdb25</doaj_id><sourcerecordid>A597543017</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-8e6dc289656c02adf11cd0ec5f78f98392009a4122d87b505f19e2a8e7d8871c3</originalsourceid><addsrcrecordid>eNqNk01v1DAQhiMEoqXwDxBEQkJw2MV24i8OSKuqlJUqVeLrwsHy2pNdr5J4iZ3C_nscNq02qAeUQ6LJM68978xk2XOM5rjg-N3W912r6_nOtzBHhGAu0YPsFMuCzBhBxcOj75PsSQhbhGghGHucnRS4pGUh2Wn247LeG2icyY1vY-frXDe-XefW6RXEFN7p6KCNIXdtfhE3zu-cfp8v8rAPERo9IB3cOPiV69bmDUQ90-la--DC0-xRpesAz8b3Wfbt48XX80-zq-vL5fniamaYJHEmgFlDhGSUGUS0rTA2FoGhFReVFIUkCEldYkKs4CuKaIUlEC2AWyE4NsVZ9vKgu6t9UKMvQREiklEclzIRywNhvd6qXeca3e2V1079DfhurXSXSqlBASbCVBIzAlVJLRfEcFvQipZsZVeEJq0P42n9qgFrkjmdriei0z-t26i1v1GMY0wlSwJvRoHO_-whRNW4YKCudQu-P9xbMEqQSOirf9D7qxuptU4FuLby6VwziKoFlTx1GmGeqPk9VHrs0P40RJVL8UnC20nCMCDwO651H4Jafvn8_-z19yn7-ojdgK7jJvi6j863YQqWB9B0PoQOqjuTMVLDDty6oYYdUOMOpLQXxw26S7od-uIPidQA3g</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2281377149</pqid></control><display><type>article</type><title>Glycemic control among diabetic patients in Ethiopia: A systematic review and meta-analysis</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Gebreyohannes, Eyob Alemayehu ; Netere, Adeladlew Kassie ; Belachew, Sewunet Admasu</creator><contributor>Hirst, Jennifer A.</contributor><creatorcontrib>Gebreyohannes, Eyob Alemayehu ; Netere, Adeladlew Kassie ; Belachew, Sewunet Admasu ; Hirst, Jennifer A.</creatorcontrib><description>Ethiopia recorded the highest numbers of people with diabetes in Africa. It is not uncommon for diabetic patients to have poor glycemic control leading to a number of complications. The aim of this systematic review and meta-analysis is to evaluate the level of glycemic control among diabetic patients in Ethiopia by combining the studies from the existing literature.
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was employed to plan and conduct this review. A comprehensive electronic-based literature search was conducted in the databases of MEDLINE, HINARI, GOOGLE SCHOLAR, and SCIENCEDIRECT. Open meta-analyst software was used to perform meta-analyses. Proportions of good glycemic control among diabetic patients was calculated. Odds ratio was also calculated to check the presence of statistically significant difference in glycemic control among patients with type 1 and type 2 diabetes.
A total of 22 studies were included in the final analysis. Meta-analysis of 16 studies showed that only one-third of patients [34.4% (95% CI: 27.9%-40.9%), p<0.001] achieving good glycemic control based on fasting plasma glucose measurements. Similar to the studies that used fasting plasma glucose, the rate of good glycemic control was found to be 33.2% [(95% CI: 21.8%-44.6%), p<0.001] based on glycosylated hemoglobin measurements. There was no statistically significant difference in the rates of glycemic control between patients with type 1 and type 2 diabetes (p = 0.167).
High proportion of diabetic patients were unable to achieve good glycemic control. There was no difference in glycemic control among type 1 and type 2 diabetic patients.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0221790</identifier><identifier>PMID: 31454396</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Biology and Life Sciences ; Blood glucose ; Blood Glucose - analysis ; Care and treatment ; Complications ; Control ; Demographic aspects ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (insulin dependent) ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 2 - blood ; Diabetes Mellitus, Type 2 - complications ; Diabetes therapy ; Diabetics ; Ethiopia ; Fasting ; Fasting - blood ; Female ; Glucose ; Glycated Hemoglobin A - metabolism ; Glycosylated hemoglobin ; Health sciences ; Hemoglobin ; Hemoglobins ; Humans ; Hyperglycemia ; Hyperglycemia - complications ; Insulin ; Laboratory testing ; Literature reviews ; Male ; Mathematical analysis ; Medical research ; Medicine and Health Sciences ; Meta-analysis ; Metabolism ; Middle Aged ; Pharmacy ; Physical Sciences ; Publication Bias ; Research and Analysis Methods ; Scientific papers ; Search engines ; Statistical analysis ; Statistical significance ; Studies ; Systematic review ; Type 2 diabetes</subject><ispartof>PloS one, 2019-08, Vol.14 (8), p.e0221790-e0221790</ispartof><rights>COPYRIGHT 2019 Public Library of Science</rights><rights>2019 Gebreyohannes et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 Gebreyohannes et al 2019 Gebreyohannes et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-8e6dc289656c02adf11cd0ec5f78f98392009a4122d87b505f19e2a8e7d8871c3</citedby><cites>FETCH-LOGICAL-c692t-8e6dc289656c02adf11cd0ec5f78f98392009a4122d87b505f19e2a8e7d8871c3</cites><orcidid>0000-0003-0519-509X ; 0000-0002-0075-4553</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711596/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711596/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31454396$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Hirst, Jennifer A.</contributor><creatorcontrib>Gebreyohannes, Eyob Alemayehu</creatorcontrib><creatorcontrib>Netere, Adeladlew Kassie</creatorcontrib><creatorcontrib>Belachew, Sewunet Admasu</creatorcontrib><title>Glycemic control among diabetic patients in Ethiopia: A systematic review and meta-analysis</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Ethiopia recorded the highest numbers of people with diabetes in Africa. It is not uncommon for diabetic patients to have poor glycemic control leading to a number of complications. The aim of this systematic review and meta-analysis is to evaluate the level of glycemic control among diabetic patients in Ethiopia by combining the studies from the existing literature.
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was employed to plan and conduct this review. A comprehensive electronic-based literature search was conducted in the databases of MEDLINE, HINARI, GOOGLE SCHOLAR, and SCIENCEDIRECT. Open meta-analyst software was used to perform meta-analyses. Proportions of good glycemic control among diabetic patients was calculated. Odds ratio was also calculated to check the presence of statistically significant difference in glycemic control among patients with type 1 and type 2 diabetes.
A total of 22 studies were included in the final analysis. Meta-analysis of 16 studies showed that only one-third of patients [34.4% (95% CI: 27.9%-40.9%), p<0.001] achieving good glycemic control based on fasting plasma glucose measurements. Similar to the studies that used fasting plasma glucose, the rate of good glycemic control was found to be 33.2% [(95% CI: 21.8%-44.6%), p<0.001] based on glycosylated hemoglobin measurements. There was no statistically significant difference in the rates of glycemic control between patients with type 1 and type 2 diabetes (p = 0.167).
High proportion of diabetic patients were unable to achieve good glycemic control. There was no difference in glycemic control among type 1 and type 2 diabetic patients.</description><subject>Biology and Life Sciences</subject><subject>Blood glucose</subject><subject>Blood Glucose - analysis</subject><subject>Care and treatment</subject><subject>Complications</subject><subject>Control</subject><subject>Demographic aspects</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (insulin dependent)</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes Mellitus, Type 2 - blood</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes therapy</subject><subject>Diabetics</subject><subject>Ethiopia</subject><subject>Fasting</subject><subject>Fasting - blood</subject><subject>Female</subject><subject>Glucose</subject><subject>Glycated Hemoglobin A - metabolism</subject><subject>Glycosylated hemoglobin</subject><subject>Health sciences</subject><subject>Hemoglobin</subject><subject>Hemoglobins</subject><subject>Humans</subject><subject>Hyperglycemia</subject><subject>Hyperglycemia - complications</subject><subject>Insulin</subject><subject>Laboratory testing</subject><subject>Literature reviews</subject><subject>Male</subject><subject>Mathematical analysis</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Meta-analysis</subject><subject>Metabolism</subject><subject>Middle Aged</subject><subject>Pharmacy</subject><subject>Physical Sciences</subject><subject>Publication Bias</subject><subject>Research and Analysis Methods</subject><subject>Scientific papers</subject><subject>Search engines</subject><subject>Statistical analysis</subject><subject>Statistical significance</subject><subject>Studies</subject><subject>Systematic review</subject><subject>Type 2 diabetes</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk01v1DAQhiMEoqXwDxBEQkJw2MV24i8OSKuqlJUqVeLrwsHy2pNdr5J4iZ3C_nscNq02qAeUQ6LJM68978xk2XOM5rjg-N3W912r6_nOtzBHhGAu0YPsFMuCzBhBxcOj75PsSQhbhGghGHucnRS4pGUh2Wn247LeG2icyY1vY-frXDe-XefW6RXEFN7p6KCNIXdtfhE3zu-cfp8v8rAPERo9IB3cOPiV69bmDUQ90-la--DC0-xRpesAz8b3Wfbt48XX80-zq-vL5fniamaYJHEmgFlDhGSUGUS0rTA2FoGhFReVFIUkCEldYkKs4CuKaIUlEC2AWyE4NsVZ9vKgu6t9UKMvQREiklEclzIRywNhvd6qXeca3e2V1079DfhurXSXSqlBASbCVBIzAlVJLRfEcFvQipZsZVeEJq0P42n9qgFrkjmdriei0z-t26i1v1GMY0wlSwJvRoHO_-whRNW4YKCudQu-P9xbMEqQSOirf9D7qxuptU4FuLby6VwziKoFlTx1GmGeqPk9VHrs0P40RJVL8UnC20nCMCDwO651H4Jafvn8_-z19yn7-ojdgK7jJvi6j863YQqWB9B0PoQOqjuTMVLDDty6oYYdUOMOpLQXxw26S7od-uIPidQA3g</recordid><startdate>20190827</startdate><enddate>20190827</enddate><creator>Gebreyohannes, Eyob Alemayehu</creator><creator>Netere, Adeladlew Kassie</creator><creator>Belachew, Sewunet Admasu</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-0519-509X</orcidid><orcidid>https://orcid.org/0000-0002-0075-4553</orcidid></search><sort><creationdate>20190827</creationdate><title>Glycemic control among diabetic patients in Ethiopia: A systematic review and meta-analysis</title><author>Gebreyohannes, Eyob Alemayehu ; Netere, Adeladlew Kassie ; Belachew, Sewunet Admasu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-8e6dc289656c02adf11cd0ec5f78f98392009a4122d87b505f19e2a8e7d8871c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Biology and Life Sciences</topic><topic>Blood glucose</topic><topic>Blood Glucose - analysis</topic><topic>Care and treatment</topic><topic>Complications</topic><topic>Control</topic><topic>Demographic aspects</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes mellitus (insulin dependent)</topic><topic>Diabetes mellitus (non-insulin dependent)</topic><topic>Diabetes Mellitus, Type 2 - blood</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diabetes therapy</topic><topic>Diabetics</topic><topic>Ethiopia</topic><topic>Fasting</topic><topic>Fasting - blood</topic><topic>Female</topic><topic>Glucose</topic><topic>Glycated Hemoglobin A - metabolism</topic><topic>Glycosylated hemoglobin</topic><topic>Health sciences</topic><topic>Hemoglobin</topic><topic>Hemoglobins</topic><topic>Humans</topic><topic>Hyperglycemia</topic><topic>Hyperglycemia - complications</topic><topic>Insulin</topic><topic>Laboratory testing</topic><topic>Literature reviews</topic><topic>Male</topic><topic>Mathematical analysis</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Meta-analysis</topic><topic>Metabolism</topic><topic>Middle Aged</topic><topic>Pharmacy</topic><topic>Physical Sciences</topic><topic>Publication Bias</topic><topic>Research and Analysis Methods</topic><topic>Scientific papers</topic><topic>Search engines</topic><topic>Statistical analysis</topic><topic>Statistical significance</topic><topic>Studies</topic><topic>Systematic review</topic><topic>Type 2 diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gebreyohannes, Eyob Alemayehu</creatorcontrib><creatorcontrib>Netere, Adeladlew Kassie</creatorcontrib><creatorcontrib>Belachew, Sewunet Admasu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gebreyohannes, Eyob Alemayehu</au><au>Netere, Adeladlew Kassie</au><au>Belachew, Sewunet Admasu</au><au>Hirst, Jennifer A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glycemic control among diabetic patients in Ethiopia: A systematic review and meta-analysis</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2019-08-27</date><risdate>2019</risdate><volume>14</volume><issue>8</issue><spage>e0221790</spage><epage>e0221790</epage><pages>e0221790-e0221790</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Ethiopia recorded the highest numbers of people with diabetes in Africa. It is not uncommon for diabetic patients to have poor glycemic control leading to a number of complications. The aim of this systematic review and meta-analysis is to evaluate the level of glycemic control among diabetic patients in Ethiopia by combining the studies from the existing literature.
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was employed to plan and conduct this review. A comprehensive electronic-based literature search was conducted in the databases of MEDLINE, HINARI, GOOGLE SCHOLAR, and SCIENCEDIRECT. Open meta-analyst software was used to perform meta-analyses. Proportions of good glycemic control among diabetic patients was calculated. Odds ratio was also calculated to check the presence of statistically significant difference in glycemic control among patients with type 1 and type 2 diabetes.
A total of 22 studies were included in the final analysis. Meta-analysis of 16 studies showed that only one-third of patients [34.4% (95% CI: 27.9%-40.9%), p<0.001] achieving good glycemic control based on fasting plasma glucose measurements. Similar to the studies that used fasting plasma glucose, the rate of good glycemic control was found to be 33.2% [(95% CI: 21.8%-44.6%), p<0.001] based on glycosylated hemoglobin measurements. There was no statistically significant difference in the rates of glycemic control between patients with type 1 and type 2 diabetes (p = 0.167).
High proportion of diabetic patients were unable to achieve good glycemic control. There was no difference in glycemic control among type 1 and type 2 diabetic patients.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>31454396</pmid><doi>10.1371/journal.pone.0221790</doi><tpages>e0221790</tpages><orcidid>https://orcid.org/0000-0003-0519-509X</orcidid><orcidid>https://orcid.org/0000-0002-0075-4553</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2019-08, Vol.14 (8), p.e0221790-e0221790 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2281377149 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Biology and Life Sciences Blood glucose Blood Glucose - analysis Care and treatment Complications Control Demographic aspects Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes therapy Diabetics Ethiopia Fasting Fasting - blood Female Glucose Glycated Hemoglobin A - metabolism Glycosylated hemoglobin Health sciences Hemoglobin Hemoglobins Humans Hyperglycemia Hyperglycemia - complications Insulin Laboratory testing Literature reviews Male Mathematical analysis Medical research Medicine and Health Sciences Meta-analysis Metabolism Middle Aged Pharmacy Physical Sciences Publication Bias Research and Analysis Methods Scientific papers Search engines Statistical analysis Statistical significance Studies Systematic review Type 2 diabetes |
| title | Glycemic control among diabetic patients in Ethiopia: A systematic review and meta-analysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T16%3A29%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Glycemic%20control%20among%20diabetic%20patients%20in%20Ethiopia:%20A%20systematic%20review%20and%20meta-analysis&rft.jtitle=PloS%20one&rft.au=Gebreyohannes,%20Eyob%20Alemayehu&rft.date=2019-08-27&rft.volume=14&rft.issue=8&rft.spage=e0221790&rft.epage=e0221790&rft.pages=e0221790-e0221790&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0221790&rft_dat=%3Cgale_plos_%3EA597543017%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2281377149&rft_id=info:pmid/31454396&rft_galeid=A597543017&rft_doaj_id=oai_doaj_org_article_e128cf9162ef45d782c7d35f546bdb25&rfr_iscdi=true |