How can the occurrence of delayed elevation of thyroid stimulating hormone in preterm infants born between 35 and 36 weeks gestation be predicted?
We evaluated frequency and risk factors of delayed TSH elevation (dTSH) and investigated follow-up outcomes in the dTSH group with venous TSH (v-TSH) levels of 6-20 mU/L according to whether late preterm infants born at gestational age (GA) 35-36 weeks had risk factors. The medical records of 810 ne...
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| creator | Heo, You Jung Lee, Young Ah Lee, Bora Lee, Yun Jeong Lim, Youn Hee Chung, Hye Rim Shin, Seung Han Shin, Choong Ho Yang, Sei Won |
| description | We evaluated frequency and risk factors of delayed TSH elevation (dTSH) and investigated follow-up outcomes in the dTSH group with venous TSH (v-TSH) levels of 6-20 mU/L according to whether late preterm infants born at gestational age (GA) 35-36 weeks had risk factors.
The medical records of 810 neonates (414 boys) born at Seoul National University Hospital who had a normal neonatal screening test (NST) and underwent the first repeat venous blood test at 10-21 days post birth were reviewed.
Seventy-three (9.0%) neonates showed dTSH, defined as a v-TSH level ≥6.0 mU/L, 12 of whom (1.5%) were started on levothyroxine medication. A multivariate-adjusted model indicated that a low birth weight (LBW |
| doi_str_mv | 10.1371/journal.pone.0220240 |
| format | Article |
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The medical records of 810 neonates (414 boys) born at Seoul National University Hospital who had a normal neonatal screening test (NST) and underwent the first repeat venous blood test at 10-21 days post birth were reviewed.
Seventy-three (9.0%) neonates showed dTSH, defined as a v-TSH level ≥6.0 mU/L, 12 of whom (1.5%) were started on levothyroxine medication. A multivariate-adjusted model indicated that a low birth weight (LBW <2,000 g), a congenital anomaly, and exposure to iodine contrast media (ICM) were significant predictors for dTSH (all p < 0.05). Among these 73 dTSH infants, all 5 infants with TSH levels ≥20 mU/L began levothyroxine medication, and 6 of 16 infants with v-TSH levels of 10-20 mU/L were indicated for levothyroxine, regardless of coexisting risk factors. However, only 1 of 52 infants with v-TSH levels of 6-10 mU/L who had a congenital anomaly was indicated for levothyroxine. All healthy late preterm infants, including LBW and multiple births, with v-TSH levels of 6-10 mU/L exhibited normal thyroid function.
dTSH was detected in 9.0% and levothyroxine was indicated in 1.5% of infants born at GA 35-36 weeks, particularly those with a LBW, a congenital anomaly, or history of ICM exposure. Either levothyroxine or retesting is indicated for late preterm neonates with TSH levels ≥10 mU/L regardless of risk factors. If healthy preterm neonates show v-TSH levels of 6-10 mU/L, a second repeat test may not be necessary; however, further studies are required to set a threshold for retesting.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0220240</identifier><identifier>PMID: 31442229</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Biology and Life Sciences ; Birth weight ; Blood tests ; Congenital anomalies ; Congenital diseases ; Contrast agents ; Contrast media ; Drug dosages ; Drugs ; Endocrinology ; Exposure ; Female ; Genetic disorders ; Gestation ; Gestational Age ; Glycoproteins ; Health risks ; Health screening ; Hormones ; Hospitals ; Humans ; Hypothyroidism ; In vitro fertilization ; Infant, Newborn ; Infant, Premature - metabolism ; Infants ; Intensive care ; Iodine ; Levels ; Levothyroxine ; Low birth weight ; Male ; Measurement ; Medical records ; Medical screening ; Medical tests ; Medicine ; Medicine and Health Sciences ; Multiple births ; Neonates ; Newborn babies ; Newborn infants ; Pediatrics ; People and Places ; Physiological aspects ; Pituitary hormones ; Pregnancy ; Premature babies ; Premature infants ; Risk analysis ; Risk Factors ; Thyroid ; Thyroid gland ; Thyroid-stimulating hormone ; Thyrotropin ; Thyrotropin - metabolism ; Thyroxine ; Thyroxine - pharmacology ; Time Factors</subject><ispartof>PloS one, 2019-08, Vol.14 (8), p.e0220240-e0220240</ispartof><rights>COPYRIGHT 2019 Public Library of Science</rights><rights>2019 Heo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 Heo et al 2019 Heo et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-e897ecedc9da02a14d5952ea136a00265b160540e25f3c335ccc31c769090c173</citedby><cites>FETCH-LOGICAL-c692t-e897ecedc9da02a14d5952ea136a00265b160540e25f3c335ccc31c769090c173</cites><orcidid>0000-0002-9813-1134 ; 0000-0001-9179-1247</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707626/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707626/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31442229$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Heo, You Jung</creatorcontrib><creatorcontrib>Lee, Young Ah</creatorcontrib><creatorcontrib>Lee, Bora</creatorcontrib><creatorcontrib>Lee, Yun Jeong</creatorcontrib><creatorcontrib>Lim, Youn Hee</creatorcontrib><creatorcontrib>Chung, Hye Rim</creatorcontrib><creatorcontrib>Shin, Seung Han</creatorcontrib><creatorcontrib>Shin, Choong Ho</creatorcontrib><creatorcontrib>Yang, Sei Won</creatorcontrib><title>How can the occurrence of delayed elevation of thyroid stimulating hormone in preterm infants born between 35 and 36 weeks gestation be predicted?</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>We evaluated frequency and risk factors of delayed TSH elevation (dTSH) and investigated follow-up outcomes in the dTSH group with venous TSH (v-TSH) levels of 6-20 mU/L according to whether late preterm infants born at gestational age (GA) 35-36 weeks had risk factors.
The medical records of 810 neonates (414 boys) born at Seoul National University Hospital who had a normal neonatal screening test (NST) and underwent the first repeat venous blood test at 10-21 days post birth were reviewed.
Seventy-three (9.0%) neonates showed dTSH, defined as a v-TSH level ≥6.0 mU/L, 12 of whom (1.5%) were started on levothyroxine medication. A multivariate-adjusted model indicated that a low birth weight (LBW <2,000 g), a congenital anomaly, and exposure to iodine contrast media (ICM) were significant predictors for dTSH (all p < 0.05). Among these 73 dTSH infants, all 5 infants with TSH levels ≥20 mU/L began levothyroxine medication, and 6 of 16 infants with v-TSH levels of 10-20 mU/L were indicated for levothyroxine, regardless of coexisting risk factors. However, only 1 of 52 infants with v-TSH levels of 6-10 mU/L who had a congenital anomaly was indicated for levothyroxine. All healthy late preterm infants, including LBW and multiple births, with v-TSH levels of 6-10 mU/L exhibited normal thyroid function.
dTSH was detected in 9.0% and levothyroxine was indicated in 1.5% of infants born at GA 35-36 weeks, particularly those with a LBW, a congenital anomaly, or history of ICM exposure. Either levothyroxine or retesting is indicated for late preterm neonates with TSH levels ≥10 mU/L regardless of risk factors. If healthy preterm neonates show v-TSH levels of 6-10 mU/L, a second repeat test may not be necessary; however, further studies are required to set a threshold for retesting.</description><subject>Biology and Life Sciences</subject><subject>Birth weight</subject><subject>Blood tests</subject><subject>Congenital anomalies</subject><subject>Congenital diseases</subject><subject>Contrast agents</subject><subject>Contrast media</subject><subject>Drug dosages</subject><subject>Drugs</subject><subject>Endocrinology</subject><subject>Exposure</subject><subject>Female</subject><subject>Genetic disorders</subject><subject>Gestation</subject><subject>Gestational Age</subject><subject>Glycoproteins</subject><subject>Health risks</subject><subject>Health screening</subject><subject>Hormones</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypothyroidism</subject><subject>In vitro fertilization</subject><subject>Infant, Newborn</subject><subject>Infant, Premature - metabolism</subject><subject>Infants</subject><subject>Intensive care</subject><subject>Iodine</subject><subject>Levels</subject><subject>Levothyroxine</subject><subject>Low birth weight</subject><subject>Male</subject><subject>Measurement</subject><subject>Medical records</subject><subject>Medical screening</subject><subject>Medical tests</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Multiple births</subject><subject>Neonates</subject><subject>Newborn babies</subject><subject>Newborn infants</subject><subject>Pediatrics</subject><subject>People and Places</subject><subject>Physiological aspects</subject><subject>Pituitary hormones</subject><subject>Pregnancy</subject><subject>Premature babies</subject><subject>Premature infants</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Thyroid</subject><subject>Thyroid gland</subject><subject>Thyroid-stimulating hormone</subject><subject>Thyrotropin</subject><subject>Thyrotropin - metabolism</subject><subject>Thyroxine</subject><subject>Thyroxine - pharmacology</subject><subject>Time Factors</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk81u1DAQxyMEoqXwBggsISE47OKP2N5cQFUFdKVKlfi6Wo4z2c2S2FvbadnX4Ilx2LTaoB6QD5mMf_P3eMaTZc8JnhMmybuN673V7XzrLMwxpZjm-EF2TApGZ4Ji9vDAPsqehLDBmLOFEI-zI0bynFJaHGe_z90NMtqiuAbkjOm9B2uSWaMKWr2DCkEL1zo2zg7OuN5511QoxKbr2-S2K7R2vktJoMairYcIvktmrW0MqHTeohLiDYBFjCNtK8QESr8_A1pBiHvhEobIqjERqg9Ps0e1bgM8G78n2fdPH7-dnc8uLj8vz04vZkYUNM5gUUgwUJmi0phqkle84BQ0YUJjTAUvicA8x0B5zQxj3BjDiJGiwAU2RLKT7OVed9u6oMZyBkWpLDDFnLBELPdE5fRGbX3Tab9TTjfqr8P5ldI-NqYFhXOJeSnLnMhFTiXXJRNGl4tFEpJcVknr_XhaX3Ypa7DR63YiOt2xzVqt3LUSEktBRRJ4Mwp4d9Wn0qmuCQbaVltw_ZD3ghNMCCsS-uof9P7bjdRKpwukjrl0rhlE1SkvJKXpleWJmt9DpVVB15jU9rpJ_knA20lAYiL8iivdh6CWX7_8P3v5Y8q-PmDXoNu4Dq7thwcUpmC-B413IXio74pMsBpG57YaahgdNY5OCntx2KC7oNtZYX8AiwATUg</recordid><startdate>20190823</startdate><enddate>20190823</enddate><creator>Heo, You Jung</creator><creator>Lee, Young Ah</creator><creator>Lee, Bora</creator><creator>Lee, Yun Jeong</creator><creator>Lim, Youn Hee</creator><creator>Chung, Hye Rim</creator><creator>Shin, Seung Han</creator><creator>Shin, Choong Ho</creator><creator>Yang, Sei Won</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-9813-1134</orcidid><orcidid>https://orcid.org/0000-0001-9179-1247</orcidid></search><sort><creationdate>20190823</creationdate><title>How can the occurrence of delayed elevation of thyroid stimulating hormone in preterm infants born between 35 and 36 weeks gestation be predicted?</title><author>Heo, You Jung ; Lee, Young Ah ; Lee, Bora ; Lee, Yun Jeong ; Lim, Youn Hee ; Chung, Hye Rim ; Shin, Seung Han ; Shin, Choong Ho ; Yang, Sei Won</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-e897ecedc9da02a14d5952ea136a00265b160540e25f3c335ccc31c769090c173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Biology and Life Sciences</topic><topic>Birth weight</topic><topic>Blood tests</topic><topic>Congenital anomalies</topic><topic>Congenital diseases</topic><topic>Contrast agents</topic><topic>Contrast media</topic><topic>Drug dosages</topic><topic>Drugs</topic><topic>Endocrinology</topic><topic>Exposure</topic><topic>Female</topic><topic>Genetic disorders</topic><topic>Gestation</topic><topic>Gestational Age</topic><topic>Glycoproteins</topic><topic>Health risks</topic><topic>Health screening</topic><topic>Hormones</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypothyroidism</topic><topic>In vitro fertilization</topic><topic>Infant, Newborn</topic><topic>Infant, Premature - metabolism</topic><topic>Infants</topic><topic>Intensive care</topic><topic>Iodine</topic><topic>Levels</topic><topic>Levothyroxine</topic><topic>Low birth weight</topic><topic>Male</topic><topic>Measurement</topic><topic>Medical records</topic><topic>Medical screening</topic><topic>Medical tests</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Multiple births</topic><topic>Neonates</topic><topic>Newborn babies</topic><topic>Newborn infants</topic><topic>Pediatrics</topic><topic>People and Places</topic><topic>Physiological aspects</topic><topic>Pituitary hormones</topic><topic>Pregnancy</topic><topic>Premature babies</topic><topic>Premature infants</topic><topic>Risk analysis</topic><topic>Risk Factors</topic><topic>Thyroid</topic><topic>Thyroid gland</topic><topic>Thyroid-stimulating hormone</topic><topic>Thyrotropin</topic><topic>Thyrotropin - metabolism</topic><topic>Thyroxine</topic><topic>Thyroxine - pharmacology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Heo, You Jung</creatorcontrib><creatorcontrib>Lee, Young Ah</creatorcontrib><creatorcontrib>Lee, Bora</creatorcontrib><creatorcontrib>Lee, Yun Jeong</creatorcontrib><creatorcontrib>Lim, Youn Hee</creatorcontrib><creatorcontrib>Chung, Hye Rim</creatorcontrib><creatorcontrib>Shin, Seung Han</creatorcontrib><creatorcontrib>Shin, Choong Ho</creatorcontrib><creatorcontrib>Yang, Sei Won</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Heo, You Jung</au><au>Lee, Young Ah</au><au>Lee, Bora</au><au>Lee, Yun Jeong</au><au>Lim, Youn Hee</au><au>Chung, Hye Rim</au><au>Shin, Seung Han</au><au>Shin, Choong Ho</au><au>Yang, Sei Won</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How can the occurrence of delayed elevation of thyroid stimulating hormone in preterm infants born between 35 and 36 weeks gestation be predicted?</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2019-08-23</date><risdate>2019</risdate><volume>14</volume><issue>8</issue><spage>e0220240</spage><epage>e0220240</epage><pages>e0220240-e0220240</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>We evaluated frequency and risk factors of delayed TSH elevation (dTSH) and investigated follow-up outcomes in the dTSH group with venous TSH (v-TSH) levels of 6-20 mU/L according to whether late preterm infants born at gestational age (GA) 35-36 weeks had risk factors.
The medical records of 810 neonates (414 boys) born at Seoul National University Hospital who had a normal neonatal screening test (NST) and underwent the first repeat venous blood test at 10-21 days post birth were reviewed.
Seventy-three (9.0%) neonates showed dTSH, defined as a v-TSH level ≥6.0 mU/L, 12 of whom (1.5%) were started on levothyroxine medication. A multivariate-adjusted model indicated that a low birth weight (LBW <2,000 g), a congenital anomaly, and exposure to iodine contrast media (ICM) were significant predictors for dTSH (all p < 0.05). Among these 73 dTSH infants, all 5 infants with TSH levels ≥20 mU/L began levothyroxine medication, and 6 of 16 infants with v-TSH levels of 10-20 mU/L were indicated for levothyroxine, regardless of coexisting risk factors. However, only 1 of 52 infants with v-TSH levels of 6-10 mU/L who had a congenital anomaly was indicated for levothyroxine. All healthy late preterm infants, including LBW and multiple births, with v-TSH levels of 6-10 mU/L exhibited normal thyroid function.
dTSH was detected in 9.0% and levothyroxine was indicated in 1.5% of infants born at GA 35-36 weeks, particularly those with a LBW, a congenital anomaly, or history of ICM exposure. Either levothyroxine or retesting is indicated for late preterm neonates with TSH levels ≥10 mU/L regardless of risk factors. If healthy preterm neonates show v-TSH levels of 6-10 mU/L, a second repeat test may not be necessary; however, further studies are required to set a threshold for retesting.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>31442229</pmid><doi>10.1371/journal.pone.0220240</doi><tpages>e0220240</tpages><orcidid>https://orcid.org/0000-0002-9813-1134</orcidid><orcidid>https://orcid.org/0000-0001-9179-1247</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2019-08, Vol.14 (8), p.e0220240-e0220240 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2279020513 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Biology and Life Sciences Birth weight Blood tests Congenital anomalies Congenital diseases Contrast agents Contrast media Drug dosages Drugs Endocrinology Exposure Female Genetic disorders Gestation Gestational Age Glycoproteins Health risks Health screening Hormones Hospitals Humans Hypothyroidism In vitro fertilization Infant, Newborn Infant, Premature - metabolism Infants Intensive care Iodine Levels Levothyroxine Low birth weight Male Measurement Medical records Medical screening Medical tests Medicine Medicine and Health Sciences Multiple births Neonates Newborn babies Newborn infants Pediatrics People and Places Physiological aspects Pituitary hormones Pregnancy Premature babies Premature infants Risk analysis Risk Factors Thyroid Thyroid gland Thyroid-stimulating hormone Thyrotropin Thyrotropin - metabolism Thyroxine Thyroxine - pharmacology Time Factors |
| title | How can the occurrence of delayed elevation of thyroid stimulating hormone in preterm infants born between 35 and 36 weeks gestation be predicted? |
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