Genetically regulated gene expression underlies lipid traits in Hispanic cohorts

Plasma lipid levels are risk factors for cardiovascular disease, a leading cause of death worldwide. While many studies have been conducted in genetic variation underlying lipid levels, they mainly comprise individuals of European ancestry and thus their transferability to non-European populations i...

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Veröffentlicht in:	PloS one 2019-08, Vol.14 (8), p.e0220827
Hauptverfasser:	Andaleon, Angela, Mogil, Lauren S, Wheeler, Heather E
Format:	Artikel
Sprache:	eng
Schlagworte:	Admixtures Analysis Arteriosclerosis Atherosclerosis Bioinformatics Biology Biology and Life Sciences Blood lipids Cardiovascular disease Cardiovascular diseases CCL22 protein Consortia Death Ethnic factors Ethnicity Female Gene expression Gene Expression Regulation Gene mapping Gene regulation Genes Genetic aspects Genetic diversity Genetic regulation Genetics Genome-Wide Association Study Genomes Genomics Genotype & phenotype Health Health risks Hispanic Americans Hispanic or Latino - genetics Humans Intercellular adhesion molecule 1 Levels Lipids Lipids - blood Lipids - genetics Male Mapping Medicine and Health Sciences Obesity People and Places Phenotype Phenotypes Physical Sciences Physiological aspects Polymorphism, Single Nucleotide Population Population studies Populations Quantitative genetics Quantitative Trait Loci Research and Analysis Methods Risk analysis Risk factors Single-nucleotide polymorphism Studies Tissues White People - genetics
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