Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation

Naja annulifera is a medically important venomous snake occurring in some of the countries in Sub-Saharan Africa. Accidental bites result in severe coagulation disturbances, systemic inflammation and heart damage, as reported in dogs, and death, by respiratory arrest, in humans. Despite the medical...

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Veröffentlicht in:	PLoS neglected tropical diseases 2019-01, Vol.13 (1), p.e0007017
Hauptverfasser:	Silva-de-França, Felipe, Villas-Boas, Isadora Maria, Serrano, Solange Maria de Toledo, Cogliati, Bruno, Chudzinski, Sonia Aparecida de Andrade, Lopes, Priscila Hess, Kitano, Eduardo Shigueo, Okamoto, Cinthya Kimori, Tambourgi, Denise V
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animal bites Animal models Animals Anti-inflammatory agents Antibodies Anticoagulants Antivenins - pharmacology Antivenom Biological products Biology and Life Sciences Bites Bites (Injuries) Care and treatment Coagulation Cobra venom factor Cobras Components Cysteine Cystine Cytotoxicity Damage Death Defence mechanisms Dogs Edema Elapid Venoms - analysis Elapid Venoms - toxicity Female Haemorrhage Health aspects Heart Hemorrhage Hyaluronoglucosaminidase - analysis Immune response Immune response (humoral) Immune system Immunity Immunogenicity Immunosuppressive agents Inflammation Keratinocytes L-Amino Acid Oxidase - analysis L-Amino-acid oxidase Laboratories Lungs Male Medical importance Medicine and Health Sciences Metalloproteases - analysis Mice Mice, Inbred BALB C Molecular weight Mortality Naja Naja annulifera Oxidases Pathogenesis Pathogens Phosphatase Phospholipase A2 Phospholipases Phospholipases A2 - analysis Proteinase Proteins Proteomics Research and Analysis Methods Serine Serine Proteases - analysis Serine proteinase Snake bites Snakes Thiols Toxins Tropical diseases Venom Venomous snakes Venoms Veterinary medicine
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