Identification of divergent Leishmania (Viannia) braziliensis ecotypes derived from a geographically restricted area through whole genome analysis

Leishmania braziliensis, the main etiological agent of cutaneous leishmaniasis (CL) in Latin America, is characterized by major differences in basic biology in comparison with better-known Leishmania species. It is also associated with a high phenotypic and possibly genetic diversity that need to be...

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Veröffentlicht in:	PLoS neglected tropical diseases 2019-06, Vol.13 (6), p.e0007382
Hauptverfasser:	S L Figueiredo de Sá, Bruna, Rezende, Antonio M, Melo Neto, Osvaldo P de, Brito, Maria Edileuza F de, Brandão Filho, Sinval P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Analytical methods Aneuploidy Biodiversity Biological evolution Biology Biology and Life Sciences Brazil Care and treatment Chromosomes Clustering Computer and Information Sciences Cutaneous leishmaniasis DNA sequencing Ecotype Ecotypes Electrophoresis Endemic species Enzymes Epidemiology Etiology Evolution Gene sequencing Genes Genetic aspects Genetic diversity Genetic polymorphisms Genetic Variation Genomes Genomics Heat shock Heat shock proteins Heterozygosity Hsp70 protein Humans Identification Immunology Leishmania Leishmania braziliensis - classification Leishmania braziliensis - genetics Leishmania braziliensis - isolation & purification Leishmaniasis Leishmaniasis, Cutaneous - parasitology Loci Nucleotides Parasites Parasitic diseases Parasitology People and places Phylogenetics Phylogeny Polymorphism, Single Nucleotide Research and Analysis Methods Risk factors Sequence Analysis, DNA Sequencing Single nucleotide polymorphisms Single-nucleotide polymorphism Trends Tropical diseases Urban environments Vector-borne diseases Viruses Whole Genome Sequencing
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