Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania

Hybrid genotypes have been repeatedly described among natural isolates of Leishmania, and the recovery of experimental hybrids from sand flies co-infected with different strains or species of Leishmania has formally demonstrated that members of the genus possess the machinery for genetic exchange. A...

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Veröffentlicht in:	PLoS genetics 2019-05, Vol.15 (5), p.e1008042-e1008042
Hauptverfasser:	Inbar, Ehud, Shaik, Jahangheer, Iantorno, Stefano A, Romano, Audrey, Nzelu, Chukwunonso O, Owens, Katherine, Sanders, Mandy J, Dobson, Deborah, Cotton, James A, Grigg, Michael E, Beverley, Stephen M, Sacks, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal reproduction Animals Base Sequence Biology and Life Sciences Cell culture Cell division Cell fusion Chimera Chromosome Mapping Crosses, Genetic DNA sequencing Evolution Gene mapping Genes Genetic analysis Genetic aspects Genetic crosses Genetic recombination Genome, Protozoan Genomes Genomics Genotype Genotypes Heredity Heterozygosity Hybridization Hybrids Infections Infectious diseases Inheritance Patterns Insect Vectors - parasitology Laboratories Leishmania Leishmania infantum - genetics Leishmania infantum - metabolism Leishmania major - genetics Leishmania major - metabolism Leishmania tropica - genetics Leishmania tropica - metabolism Loss of heterozygosity Medicine Meiosis Methods Observations Offspring Parasites Parasitic diseases Psychodidae - parasitology Recombination Recombination, Genetic Research and Analysis Methods Strains (organisms) Whole Genome Sequencing
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