I_MDS: an inflammatory bowel disease molecular activity score to classify patients with differing disease-driving pathways and therapeutic response to anti-TNF treatment

Crohn's disease and ulcerative colitis are driven by both common and distinct underlying mechanisms of pathobiology. Both diseases, exhibit heterogeneity underscored by the variable clinical responses to therapeutic interventions. We aimed to identify disease-driving pathways and classify indiv...

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Veröffentlicht in:PLoS computational biology 2019-04, Vol.15 (4), p.e1006951-e1006951
Hauptverfasser: Pavlidis, Stelios, Monast, Calixte, Loza, Matthew J, Branigan, Patrick, Chung, Kiang F, Adcock, Ian M, Guo, Yike, Rowe, Anthony, Baribaud, Frédéric
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Sprache:eng
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