Expression of suppressor of cytokine signaling 3 (SOCS3) and interleukin-6 (-174-G/C) polymorphism in atopic conditions

Hypersensitivity of the immune system is caused by elevated immunoglobulin E (IgE) levels in the serum, in response to a discrete allergen leading to allergic reactions. IgE-mediated inflammation is regulated by the cascade of defense related signaling molecules including interleukin-6 (IL-6) that p...

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Veröffentlicht in:	PloS one 2019-06, Vol.14 (6), p.e0219084-e0219084
Hauptverfasser:	Jannat, Arooma, Khan, Maryam, Shabbir, Maria, Badshah, Yasmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergens Allergic reactions Asthma Atopy Biology and Life Sciences Cascade chemical reactions Case-Control Studies Cell survival Crosstalk Cytokines Diagnosis Female Females Food allergies Gender differences Gene expression Genetic Predisposition to Disease Humans Hypersensitivity Hypersensitivity - diagnosis Hypersensitivity - genetics Immune system Immunoglobulin E Immunoglobulins Inflammation Interleukin 6 Interleukin-6 - genetics Janus kinase Kinases Levels Male Males Mast cells Medical prognosis Medicine and Health Sciences Methods Middle Aged Negative feedback Phenols Polymorphism Polymorphism, Single Nucleotide Prognosis Promoter Regions, Genetic Rhinitis Serum levels Sex Factors Signaling SOCS-3 protein Suppressor of Cytokine Signaling 3 Protein - genetics Transcription factors Transducers Young Adult
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