Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens

A 110-kDa type II transmembrane glycoprotein with dipeptidyl peptidase IV (DPPIV) activity in its extracellular region, CD26 has a multitude of biological functions and plays an important role in the regulation of inflammatory responses and tumor biology. Our work has focused on CD26 as a novel ther...

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Veröffentlicht in:PloS one 2019-06, Vol.14 (6), p.e0218330-e0218330
Hauptverfasser: Hatano, Ryo, Yamada, Taketo, Madokoro, Hiroko, Otsuka, Haruna, Komiya, Eriko, Itoh, Takumi, Narita, Yuka, Iwata, Satoshi, Yamazaki, Hiroto, Matsuoka, Shuji, Dang, Nam H, Ohnuma, Kei, Morimoto, Chikao
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Sprache:eng
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