Posterior staphylomas and scleral curvature in highly myopic children and adolescents investigated by ultra-widefield optical coherence tomography
To determine the early signs of posterior staphylomas in highly myopic eyes of younger subjects by swept-source ultra-widefield optical coherence tomography (WF-OCT). This was an observational case series study. Highly myopic subjects younger than 20 years old who were examined consecutively by prot...
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| Veröffentlicht in: | PloS one 2019-06, Vol.14 (6), p.e0218107-e0218107 |
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| creator | Tanaka, Noriko Shinohara, Kosei Yokoi, Tae Uramoto, Kengo Takahashi, Hiroyuki Onishi, Yuka Horie, Shintaro Yoshida, Takeshi Ohno-Matsui, Kyoko |
| description | To determine the early signs of posterior staphylomas in highly myopic eyes of younger subjects by swept-source ultra-widefield optical coherence tomography (WF-OCT).
This was an observational case series study. Highly myopic subjects younger than 20 years old who were examined consecutively by prototype WF-OCT were studied. High myopia was defined according to the Ministry of Health and Welfare, Japan classification. A posterior displacement of the sclera and two OCT features indicating the staphyloma edges were used as markers of a staphyloma.
Fifty-five eyes of 30 patients with the mean age of 12.3 years, and the mean axial length of 27.9 mm were studied. Seven of the 55 eyes (12.7%) had a posterior displacement of the sclera and were diagnosed as having a staphyloma. Among the two OCT features of the staphyloma edges, a gradual thinning of the choroid toward the staphyloma edge and gradual re-thickening of choroid from the staphyloma edge toward the posterior pole were found in these 7 eyes. However, the other feature of an inward protrusion of the sclera at the staphyloma edge, was obvious in only 2 eyes. The subfoveal choroid and choroid nasal to the optic disc were significantly thinner in eyes with a staphyloma than those without it.
The changes of the choroidal thickness toward the staphyloma edge with the posterior displacement of the sclera were considered an early sign which precedes an inward protrusion of sclera at the staphyloma edge. |
| doi_str_mv | 10.1371/journal.pone.0218107 |
| format | Article |
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This was an observational case series study. Highly myopic subjects younger than 20 years old who were examined consecutively by prototype WF-OCT were studied. High myopia was defined according to the Ministry of Health and Welfare, Japan classification. A posterior displacement of the sclera and two OCT features indicating the staphyloma edges were used as markers of a staphyloma.
Fifty-five eyes of 30 patients with the mean age of 12.3 years, and the mean axial length of 27.9 mm were studied. Seven of the 55 eyes (12.7%) had a posterior displacement of the sclera and were diagnosed as having a staphyloma. Among the two OCT features of the staphyloma edges, a gradual thinning of the choroid toward the staphyloma edge and gradual re-thickening of choroid from the staphyloma edge toward the posterior pole were found in these 7 eyes. However, the other feature of an inward protrusion of the sclera at the staphyloma edge, was obvious in only 2 eyes. The subfoveal choroid and choroid nasal to the optic disc were significantly thinner in eyes with a staphyloma than those without it.
The changes of the choroidal thickness toward the staphyloma edge with the posterior displacement of the sclera were considered an early sign which precedes an inward protrusion of sclera at the staphyloma edge.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0218107</identifier><identifier>PMID: 31181108</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adolescent ; Adolescents ; Biology and Life Sciences ; Child ; Children ; Choroid - diagnostic imaging ; Choroid - pathology ; Choroid Diseases - diagnostic imaging ; Curvature ; Displacement ; Early Diagnosis ; Eye ; Gene expression ; Health ; Health aspects ; Humans ; Japan ; Medical imaging ; Medical research ; Medicine and Health Sciences ; Morphology ; Myopia ; Myopia, Degenerative - complications ; Myopia, Degenerative - diagnostic imaging ; Myopia, Degenerative - pathology ; NMR ; Nuclear magnetic resonance ; Ophthalmology ; Optical Coherence Tomography ; Scleral Diseases - diagnosis ; Scleral Diseases - diagnostic imaging ; Scleral Diseases - pathology ; Studies ; Teenagers ; Thickening ; Tomography ; Tomography, Optical Coherence - methods ; Youth</subject><ispartof>PloS one, 2019-06, Vol.14 (6), p.e0218107-e0218107</ispartof><rights>COPYRIGHT 2019 Public Library of Science</rights><rights>2019 Tanaka et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 Tanaka et al 2019 Tanaka et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c758t-1ab943fedb8ddbe86f7be8b487df7074257f8a550f3d48743fde017e402f0a533</citedby><cites>FETCH-LOGICAL-c758t-1ab943fedb8ddbe86f7be8b487df7074257f8a550f3d48743fde017e402f0a533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557512/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557512/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31181108$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tanaka, Noriko</creatorcontrib><creatorcontrib>Shinohara, Kosei</creatorcontrib><creatorcontrib>Yokoi, Tae</creatorcontrib><creatorcontrib>Uramoto, Kengo</creatorcontrib><creatorcontrib>Takahashi, Hiroyuki</creatorcontrib><creatorcontrib>Onishi, Yuka</creatorcontrib><creatorcontrib>Horie, Shintaro</creatorcontrib><creatorcontrib>Yoshida, Takeshi</creatorcontrib><creatorcontrib>Ohno-Matsui, Kyoko</creatorcontrib><title>Posterior staphylomas and scleral curvature in highly myopic children and adolescents investigated by ultra-widefield optical coherence tomography</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To determine the early signs of posterior staphylomas in highly myopic eyes of younger subjects by swept-source ultra-widefield optical coherence tomography (WF-OCT).
This was an observational case series study. Highly myopic subjects younger than 20 years old who were examined consecutively by prototype WF-OCT were studied. High myopia was defined according to the Ministry of Health and Welfare, Japan classification. A posterior displacement of the sclera and two OCT features indicating the staphyloma edges were used as markers of a staphyloma.
Fifty-five eyes of 30 patients with the mean age of 12.3 years, and the mean axial length of 27.9 mm were studied. Seven of the 55 eyes (12.7%) had a posterior displacement of the sclera and were diagnosed as having a staphyloma. Among the two OCT features of the staphyloma edges, a gradual thinning of the choroid toward the staphyloma edge and gradual re-thickening of choroid from the staphyloma edge toward the posterior pole were found in these 7 eyes. However, the other feature of an inward protrusion of the sclera at the staphyloma edge, was obvious in only 2 eyes. The subfoveal choroid and choroid nasal to the optic disc were significantly thinner in eyes with a staphyloma than those without it.
The changes of the choroidal thickness toward the staphyloma edge with the posterior displacement of the sclera were considered an early sign which precedes an inward protrusion of sclera at the staphyloma edge.</description><subject>Adolescent</subject><subject>Adolescents</subject><subject>Biology and Life Sciences</subject><subject>Child</subject><subject>Children</subject><subject>Choroid - diagnostic imaging</subject><subject>Choroid - pathology</subject><subject>Choroid Diseases - diagnostic imaging</subject><subject>Curvature</subject><subject>Displacement</subject><subject>Early Diagnosis</subject><subject>Eye</subject><subject>Gene expression</subject><subject>Health</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Japan</subject><subject>Medical imaging</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Morphology</subject><subject>Myopia</subject><subject>Myopia, Degenerative - complications</subject><subject>Myopia, Degenerative - diagnostic imaging</subject><subject>Myopia, Degenerative - pathology</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Ophthalmology</subject><subject>Optical Coherence Tomography</subject><subject>Scleral Diseases - diagnosis</subject><subject>Scleral Diseases - diagnostic imaging</subject><subject>Scleral Diseases - pathology</subject><subject>Studies</subject><subject>Teenagers</subject><subject>Thickening</subject><subject>Tomography</subject><subject>Tomography, Optical Coherence - methods</subject><subject>Youth</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk12L1DAUhoso7jr6D0QLgujFjEnTNOmNsCx-DCys-HUb0ua0zZA23SRdnb_hLzbdmV1mZC-k0JbT57wn5z09SfIcoxUmDL_b2MkN0qxGO8AKZZhjxB4kp7gk2bLIEHl48H6SPPF-gxAlvCgeJycERxwjfpr8-WJ9AKetS32QY7c1tpc-lYNKfW3ASZPWk7uWYXKQ6iHtdNuZbdpv7ajrtO60UQ6GG14qa8DXMAQfyWvwQbcygEqrbTqZ4OTyl1bQaDAqtWPQ9axtO4j5NaTB9rZ18wmeJo8aaTw82z8XyY-PH76ff15eXH5an59dLGtGeVhiWZU5aUBVXKkKeNGweK9yzlTDEMszyhouKUUNUTEYUQUIM8hR1iBJCVkkL3e6o7Fe7O30IssI4znOWRGJ9Y5QVm7E6HQv3VZYqcVNwLpWSBcbMSBUJgkqMaaS8LzK6hIxrErAkpYlhUxFrff7alPVg5ptiuYeiR5_GXQnWnstCkoZxVkUeLMXcPZqiu6KXke3jZED2Gk-d57xON849EXy6h_0_u72VCtjA3pobKxbz6LijPII8YLOZVf3UPFS0Os6_nuNjvGjhLdHCZEJ8Du0cvJerL99_X_28ucx-_qA7UCa0HlrpqDt4I_BfAfWznrvoLkzGSMxr86tG2JeHbFfnZj24nBAd0m3u0L-Aky9F5g</recordid><startdate>20190610</startdate><enddate>20190610</enddate><creator>Tanaka, Noriko</creator><creator>Shinohara, Kosei</creator><creator>Yokoi, Tae</creator><creator>Uramoto, Kengo</creator><creator>Takahashi, Hiroyuki</creator><creator>Onishi, Yuka</creator><creator>Horie, Shintaro</creator><creator>Yoshida, Takeshi</creator><creator>Ohno-Matsui, Kyoko</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20190610</creationdate><title>Posterior staphylomas and scleral curvature in highly myopic children and adolescents investigated by ultra-widefield optical coherence tomography</title><author>Tanaka, Noriko ; Shinohara, Kosei ; Yokoi, Tae ; Uramoto, Kengo ; Takahashi, Hiroyuki ; Onishi, Yuka ; Horie, Shintaro ; Yoshida, Takeshi ; Ohno-Matsui, Kyoko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c758t-1ab943fedb8ddbe86f7be8b487df7074257f8a550f3d48743fde017e402f0a533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Adolescents</topic><topic>Biology and Life Sciences</topic><topic>Child</topic><topic>Children</topic><topic>Choroid - diagnostic imaging</topic><topic>Choroid - pathology</topic><topic>Choroid Diseases - diagnostic imaging</topic><topic>Curvature</topic><topic>Displacement</topic><topic>Early Diagnosis</topic><topic>Eye</topic><topic>Gene expression</topic><topic>Health</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Japan</topic><topic>Medical imaging</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Morphology</topic><topic>Myopia</topic><topic>Myopia, Degenerative - complications</topic><topic>Myopia, Degenerative - diagnostic imaging</topic><topic>Myopia, Degenerative - pathology</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Ophthalmology</topic><topic>Optical Coherence Tomography</topic><topic>Scleral Diseases - diagnosis</topic><topic>Scleral Diseases - diagnostic imaging</topic><topic>Scleral Diseases - pathology</topic><topic>Studies</topic><topic>Teenagers</topic><topic>Thickening</topic><topic>Tomography</topic><topic>Tomography, Optical Coherence - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tanaka, Noriko</au><au>Shinohara, Kosei</au><au>Yokoi, Tae</au><au>Uramoto, Kengo</au><au>Takahashi, Hiroyuki</au><au>Onishi, Yuka</au><au>Horie, Shintaro</au><au>Yoshida, Takeshi</au><au>Ohno-Matsui, Kyoko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Posterior staphylomas and scleral curvature in highly myopic children and adolescents investigated by ultra-widefield optical coherence tomography</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2019-06-10</date><risdate>2019</risdate><volume>14</volume><issue>6</issue><spage>e0218107</spage><epage>e0218107</epage><pages>e0218107-e0218107</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To determine the early signs of posterior staphylomas in highly myopic eyes of younger subjects by swept-source ultra-widefield optical coherence tomography (WF-OCT).
This was an observational case series study. Highly myopic subjects younger than 20 years old who were examined consecutively by prototype WF-OCT were studied. High myopia was defined according to the Ministry of Health and Welfare, Japan classification. A posterior displacement of the sclera and two OCT features indicating the staphyloma edges were used as markers of a staphyloma.
Fifty-five eyes of 30 patients with the mean age of 12.3 years, and the mean axial length of 27.9 mm were studied. Seven of the 55 eyes (12.7%) had a posterior displacement of the sclera and were diagnosed as having a staphyloma. Among the two OCT features of the staphyloma edges, a gradual thinning of the choroid toward the staphyloma edge and gradual re-thickening of choroid from the staphyloma edge toward the posterior pole were found in these 7 eyes. However, the other feature of an inward protrusion of the sclera at the staphyloma edge, was obvious in only 2 eyes. The subfoveal choroid and choroid nasal to the optic disc were significantly thinner in eyes with a staphyloma than those without it.
The changes of the choroidal thickness toward the staphyloma edge with the posterior displacement of the sclera were considered an early sign which precedes an inward protrusion of sclera at the staphyloma edge.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>31181108</pmid><doi>10.1371/journal.pone.0218107</doi><tpages>e0218107</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adolescents Biology and Life Sciences Child Children Choroid - diagnostic imaging Choroid - pathology Choroid Diseases - diagnostic imaging Curvature Displacement Early Diagnosis Eye Gene expression Health Health aspects Humans Japan Medical imaging Medical research Medicine and Health Sciences Morphology Myopia Myopia, Degenerative - complications Myopia, Degenerative - diagnostic imaging Myopia, Degenerative - pathology NMR Nuclear magnetic resonance Ophthalmology Optical Coherence Tomography Scleral Diseases - diagnosis Scleral Diseases - diagnostic imaging Scleral Diseases - pathology Studies Teenagers Thickening Tomography Tomography, Optical Coherence - methods Youth |
| title | Posterior staphylomas and scleral curvature in highly myopic children and adolescents investigated by ultra-widefield optical coherence tomography |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T22%3A56%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Posterior%20staphylomas%20and%20scleral%20curvature%20in%20highly%20myopic%20children%20and%20adolescents%20investigated%20by%20ultra-widefield%20optical%20coherence%20tomography&rft.jtitle=PloS%20one&rft.au=Tanaka,%20Noriko&rft.date=2019-06-10&rft.volume=14&rft.issue=6&rft.spage=e0218107&rft.epage=e0218107&rft.pages=e0218107-e0218107&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0218107&rft_dat=%3Cgale_plos_%3EA588418652%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2237841476&rft_id=info:pmid/31181108&rft_galeid=A588418652&rft_doaj_id=oai_doaj_org_article_d2a309115a384b2c9071d9e1a5995e2d&rfr_iscdi=true |