An MRI-based method to register patient-specific wall shear stress data to histology

Wall shear stress (WSS), the frictional force exerted on endothelial cells by blood flow, is hypothesised to influence atherosclerotic plaque growth and composition. We developed a methodology for image registration of MR and histology images of advanced human carotid plaques and corresponding WSS d...

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Veröffentlicht in:	PloS one 2019-06, Vol.14 (6), p.e0217271-e0217271
Hauptverfasser:	Moerman, A M, Dilba, K, Korteland, S, Poot, D H J, Klein, S, van der Lugt, A, Rouwet, E V, van Gaalen, K, Wentzel, J J, van der Steen, A F W, Gijsen, F J H, Van der Heiden, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Arteriosclerosis Atherosclerosis Atherosclerotic plaque Biology and Life Sciences Biomedical engineering Blood flow Cardiovascular disease Carotid arteries Carotid Arteries - diagnostic imaging Carotid Arteries - physiopathology Carotid Arteries - surgery Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - physiopathology Carotid Artery Diseases - surgery Composition Computational fluid dynamics Computer and Information Sciences Computer applications Computer simulation Contour matching Correlation Diagnostic imaging EDTA Endarterectomy Endothelial cells Endothelium Engineering Female Flow velocity Fluid dynamics Geometry Health informatics Hemorheology Histology Humans Hydrodynamics Image processing Image registration In vivo methods and tests Magnetic Resonance Angiography Magnetic resonance imaging Male Medicine and Health Sciences Methods NMR Nuclear magnetic resonance Nuclear medicine Physical Sciences Plaque, Atherosclerotic - diagnostic imaging Plaque, Atherosclerotic - physiopathology Plaque, Atherosclerotic - surgery Plaques Registration Relocation Research and Analysis Methods Shear Strength Shear stress Studies Transformation Wall shear stresses
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