Antibacterial activity of lysozyme-chitosan oligosaccharide conjugates (LYZOX) against Pseudomonas aeruginosa, Acinetobacter baumannii and Methicillin-resistant Staphylococcus aureus

The recent emergence of antibiotic-resistant bacteria requires the development of new antibiotics or new agents capable of enhancing antibiotic activity. This study evaluated the antibacterial activity of lysozyme-chitosan oligosaccharide conjugates (LYZOX) against Pseudomonas aeruginosa, Acinetobac...

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Veröffentlicht in:	PloS one 2019-05, Vol.14 (5), p.e0217504
Hauptverfasser:	Saito, Hiroaki, Sakakibara, Yumi, Sakata, Ayumi, Kurashige, Rie, Murakami, Daisuke, Kageshima, Hiroki, Saito, Akira, Miyazaki, Yasunari
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Acinetobacter baumannii - growth & development Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity Antibacterial agents Antibiotic resistance Antibiotics Antimicrobial agents Assaying Bacteria Biology and Life Sciences Cell death Cell membranes Cell walls Chitosan Chitosan - chemistry Chitosan - pharmacology Confocal microscopy Conjugates Disruption Drug resistance E coli Electron micrographs Electron microscopy Food Gram-negative bacteria Gram-positive bacteria Influence Intracellular Lysozyme Medicine Medicine and Health Sciences Membrane permeability Membranes Methicillin Methicillin-Resistant Staphylococcus aureus - growth & development Microbial drug resistance Micrography Microscopy Molecular weight Muramidase - chemistry Muramidase - pharmacology Novels Oligosaccharides Oligosaccharides - chemistry Oligosaccharides - pharmacology Otolaryngology Permeability Physiological aspects Pseudomonas aeruginosa Pseudomonas aeruginosa - growth & development Scanning microscopy Staphylococcal infections Staphylococcus aureus Staphylococcus aureus infections Staphylococcus infections Toxicity Toxicity testing
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