In vitro chondroprotective potential of Senna alata and Senna tora in porcine cartilage explants and their species differentiation by DNA barcoding-high resolution melting (Bar-HRM) analysis

Senna species and anthraquinone derivatives generated by these organisms, rhein and aloe-emodin, exert anti-inflammatory effects. These species present a similar morphology but produce different ingredients when they are used as medicinal products. In this study, a DNA barcoding- (Bar-) high-resolut...

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Veröffentlicht in:	PloS one 2019-04, Vol.14 (4), p.e0215664-e0215664
Hauptverfasser:	Ongchai, Siriwan, Chokchaitaweesuk, Chatchadawalai, Kongdang, Patiwat, Chomdej, Siriwadee, Buddhachat, Kittisak
Format:	Artikel
Sprache:	eng
Schlagworte:	Aloe Animals Anthraquinone Anthraquinones Anti-inflammatory agents Arthritis Backup software Bar codes Base Sequence Biochemistry Biocompatibility Biomedical materials Cartilage Cartilage - drug effects Cartilage - metabolism Cartilage - pathology Cartilage diseases Collagen Type II - metabolism Cytokines Degradation Deoxyribonucleic acid Disease Models, Animal DNA DNA Barcoding, Taxonomic - methods DNA, Ribosomal Spacer - genetics Drugs EDTA Emodin Ethanol - chemistry Explants Gene sequencing Genetic aspects Genetic research Glycosaminoglycans Herbal medicine High resolution Hyaluronic acid IL-1β Inflammation Interleukins Leaves Medicine Melting Morphology Mucopolysaccharides Osteoarthritis Osteoarthritis - metabolism Osteoarthritis - prevention & control Phytotherapy - methods Preservation Protective Agents - pharmacology Proteoglycans Proteoglycans - metabolism Raw materials Senna alata Senna Extract - chemistry Senna Extract - pharmacology Senna Plant - chemistry Senna Plant - classification Senna Plant - genetics Senna tora Sequence Homology, Nucleic Acid Species Species Specificity Stem cells Sulfates Swine Tissue engineering
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