Genome-wide association study of coronary artery calcification in asymptomatic Korean populations

Epidemiologic evidence indicates that the prevalence and severity of coronary artery disease vary depending on ethnicity. In this study, a genome-wide association study for coronary artery calcification (CAC) was performed in a Korean population-based sample of 400 subjects without prior coronary ar...

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Veröffentlicht in:	PloS one 2019-03, Vol.14 (3), p.e0214370-e0214370
Hauptverfasser:	Choi, Su-Yeon, Shin, Eunsoon, Choe, Eun Kyung, Park, Boram, Lee, Heesun, Park, Hyo Eun, Lee, Jong-Eun, Choi, Seung Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Asian Continental Ancestry Group - genetics Atherosclerosis Biology and Life Sciences Blood pressure Calcification Calcification (ectopic) Calcification (Physiology) Cardiology Cardiovascular disease CAT scans Chromosome 9 Chromosomes Computed tomography Coronary artery Coronary artery disease Coronary heart disease Coronary vessels Coronary Vessels - diagnostic imaging Coronary Vessels - pathology Cultural differences Deoxyribonucleic acid Detection equipment Diabetes Diabetes mellitus Diagnosis DNA Epidemiology Ethnicity Female Genes Genetic aspects Genetic polymorphisms Genome-wide association studies Genome-Wide Association Study Genomes Genomics Genotype Heart diseases Hospitals Humans Hypertension Internal medicine Logistic Models Male Medicine Medicine and Health Sciences Middle Aged Minority & ethnic groups Odds Ratio Polymorphism, Single Nucleotide Population Prevalence studies (Epidemiology) Regression analysis Regression models Republic of Korea Research and Analysis Methods Retrospective Studies Risk factors RNA, Long Noncoding - genetics Severity of Illness Index Sex Single nucleotide polymorphisms Single-nucleotide polymorphism Tomography Tomography, X-Ray Computed Vascular Calcification - genetics Vascular Calcification - pathology
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