Peanut skin phenolic extract attenuates hyperglycemic responses in vivo and in vitro

Diabetes affects at least 285 million people globally, and this number continues to increase. Clinical complications include impaired glucose metabolism, hyperglycemia, dyslipidemia, atherosclerosis and non-alcoholic fatty liver disease. Evidence has shown that natural phenolics play a protective ef...

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Veröffentlicht in:	PloS one 2019-03, Vol.14 (3), p.e0214591-e0214591
Hauptverfasser:	Christman, Lindsey M, Dean, Lisa L, Allen, Jonathan C, Godinez, Sofia Feng, Toomer, Ondulla T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Agriculture Antidiabetics Antioxidants Arachis - chemistry Arteriosclerosis Atherosclerosis Biology and Life Sciences Blood glucose Carcinoma Cell death Cell Survival - drug effects Cell viability Complications Dextrins Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes therapy Dose-Response Relationship, Drug Dyslipidemia EDTA Encapsulation Ethanol Fatty liver Female Food Functional foods Functional foods & nutraceuticals Glucose Glucose metabolism Glucose tolerance Glucose Tolerance Test Hep G2 Cells Hepatocytes Humans Hyperglycemia Hyperglycemia - drug therapy Hyperglycemia - metabolism Hyperglycemia - pathology In vitro methods and tests In vivo methods and tests Kinases Liver Liver diseases Male Maltodextrin Medicine and Health Sciences Metabolism Metabolites Nutrition research Nuts Oxidative stress Peanuts Phenolic compounds Phenols Phenols (Class of compounds) Phenols - pharmacology Phenols - therapeutic use Physical Sciences Plant Epidermis - chemistry Polyphenols Research and analysis methods Skin Type 2 diabetes Young Adult
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