Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms

C-reactive proteins (CRPs) are among the faster acute-phase inflammation-responses proteins encoded by one gene (hcrp) in humans and seven genes (crp1-7) in zebrafish (Danio rerio) with importance in bacterial and viral infections. In this study, we described novel preferential bindings of 25-hydrox...

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Veröffentlicht in:	PloS one 2019-01, Vol.14 (1), p.e0201509-e0201509
Hauptverfasser:	Bello-Perez, Melissa, Falco, Alberto, Novoa, Beatriz, Perez, Luis, Coll, Julio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral agents Arteriosclerosis Atherosclerosis Bacterial infections Biology and Life Sciences Biomarkers C-reactive protein C-Reactive Protein - immunology Carp Cell culture Cell Line Crosstalk Danio rerio Fish Diseases - immunology Fish Diseases - virology Hydroxycholesterols - immunology Immunology Infections Inflammation Isoforms Ligands Lipids Neurodegenerative diseases Neurological diseases Perez, Julio Physical Sciences Physiological aspects Physiology Plaques Protein binding Proteins Research and Analysis Methods Rhabdoviridae - immunology Rhabdoviridae Infections - immunology Rhabdoviridae Infections - veterinary Rhabdoviridae Infections - virology Risk factors Viral infections Viremia Virus diseases Viruses Zebrafish Zebrafish - immunology Zebrafish - virology Zebrafish Proteins - immunology
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