Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma

Fanconi anemia is a rare genome instability disorder with extreme susceptibility to squamous cell carcinoma of the head and neck and anogenital tract. In patients with this inherited disorder, the risk of head and neck cancer is 800-fold higher than in the general population, a finding which might s...

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Veröffentlicht in:	PloS one 2018-12, Vol.13 (12), p.e0209235-e0209235
Hauptverfasser:	Toptan, Tuna, Brusadelli, Marion G, Turpin, Brian, Witte, David P, Surrallés, Jordi, Velleuer, Eunike, Schramm, Martin, Dietrich, Ralf, Brakenhoff, Ruud H, Moore, Patrick S, Chang, Yuan, Wells, Susanne I
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anemia Anogenital Antigens Biology and life sciences Blood diseases Cancer Care and treatment Cell Line, Tumor Deoxyribonucleic acid DNA DNA repair Epidemiology Etiology Fanconi Anemia - immunology Fanconi Anemia - pathology Fanconi Anemia - virology Fanconi syndrome Fanconi's anemia Genetic aspects Genomes Genomic instability Head Head & neck cancer Head and neck cancer Health risks HEK293 Cells Hospitals Human papillomavirus Humans Immunohistochemistry Infections Leukemia Medicine and Health Sciences Mutation Oncology Polyomavirus Polyomavirus Infections - immunology Polyomavirus Infections - pathology Polyomavirus Infections - virology Research and Analysis Methods Risk factors Skin cancer Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - immunology Squamous Cell Carcinoma of Head and Neck - pathology Squamous Cell Carcinoma of Head and Neck - virology Stability Tumor Virus Infections - immunology Tumor Virus Infections - pathology Tumor Virus Infections - virology Tumors Viruses
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