Late vertebral side effects in long-term survivors of irradiated childhood brain tumor

Long-term side effects of the treatments are common in survivors of irradiated pediatric brain tumors. Ionizing radiation in combination with surgery and chemotherapy during childhood may reduce vertebral height and bone mineral density (BMD), and cause growth failure. The aim of this study was to e...

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Veröffentlicht in:	PloS one 2018-12, Vol.13 (12), p.e0209193
Hauptverfasser:	Jussila, Miro-Pekka, Remes, Tiina, Anttonen, Julia, Harila-Saari, Arja, Niinimäki, Jaakko, Pokka, Tytti, Koskenkorva, Päivi, Sutela, Anna, Toiviainen-Salo, Sanna, Arikoski, Pekka, Riikonen, Pekka, Arola, Mikko, Lähteenmäki, Päivi, Sirkiä, Kirsti, Rantala, Heikki, Suo-Palosaari, Maria, Ojaniemi, Marja
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Absorptiometry Absorptiometry, Photon Adult Analysis Biology and Life Sciences Body height Body mass Body mass index Body size Bone Density - radiation effects Bone mineral density Bone surgery Brain Brain cancer Brain Neoplasms - radiotherapy Brain research Brain tumors Cancer Survivors Cancer therapies Care and treatment Chemotherapy Child development Child health Childhood Children Cohort Studies Curvature Deformation mechanisms Dual energy X-ray absorptiometry Female Females Fractures Growth hormones Hospitals Humans Ionizing radiation Irradiation Leukemia Magnetic resonance Magnetic Resonance Imaging Male Males Mathematical analysis Medical imaging Medical research Medicine Medicine and Health Sciences Morphology Neuroimaging Patients Pediatrics Physics Radiation Radiation effects Radiation Injuries - diagnostic imaging Radiation Injuries - etiology Radiation therapy Radiotherapy - adverse effects Research and Analysis Methods Risk Factors Sex Factors Side effects Spinal Diseases - diagnostic imaging Spinal Diseases - etiology Spinal Injuries - diagnostic imaging Spinal Injuries - etiology Spine - diagnostic imaging Spine - radiation effects Surgery Thorax Time Factors Treatment outcome Tumors Vertebra Vertebrae Weight
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