Coordinated regulation of transcription by CcpA and the Staphylococcus aureus two-component system HptRS

The success of Staphylococcus aureus as a pathogen is due in part to its ability to adapt to changing environmental conditions using signal transduction pathways, such as metabolite- responsive regulators and two-component systems. S. aureus has a two-component system encoded by the gene pair sav022...

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Veröffentlicht in:	PloS one 2018-12, Vol.13 (12), p.e0207161-e0207161
Hauptverfasser:	Reed, Joseph M, Olson, Sean, Brees, Danielle F, Griffin, Caitlin E, Grove, Ryan A, Davis, Paul J, Kachman, Stephen D, Adamec, Jiri, Somerville, Greg A
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonia - analysis Ampicillin Anti-Bacterial Agents - pharmacology Antibiotics Bacterial Proteins - genetics Bacterial Proteins - metabolism Binding Sites Biochemistry Biology and Life Sciences Carbon Carbon sources Chromatography, High Pressure Liquid Deactivation Derepression Domains Drug resistance Environmental changes Environmental conditions Fosfomycin Fosfomycin - pharmacology Gene regulation Genes Genomes Glucose Glucose - analysis Glucose-6-phosphate Glycolysis Gram-positive bacteria Hexose Inactivation Intermediates Kinases Medicine and Health Sciences Metabolism Metabolites Monosaccharide Transport Proteins - genetics Monosaccharide Transport Proteins - metabolism Mutagenesis Pathogens Phosphates Phosphorylation Potassium Promoter Regions, Genetic Proteins Proteome - analysis Proteomics RNA polymerase Signal transduction Spectrometry, Mass, Electrospray Ionization Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - genetics Staphylococcus aureus - growth & development Staphylococcus aureus - metabolism Transcription Transcription, Genetic - drug effects Transduction Veterinary colleges Veterinary medicine
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