Anthocyanins from Cornus kousa ethanolic extract attenuate obesity in association with anti-angiogenic activities in 3T3-L1 cells by down-regulating adipogeneses and lipogenesis

Cornus kousa the Korean dogwood has been traditionally used in East Asia as therapeutic traditional medicine however biological activities of Cornus kousa have not been investigated previously. The aim of the present study was to evaluate anti-obesity activities coupled with anti-angiogenic activiti...

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Veröffentlicht in:	PloS one 2018-12, Vol.13 (12), p.e0208556-e0208556
Hauptverfasser:	Khan, Muhammad Imran, Shin, Jin Hyuk, Shin, Tai Sun, Kim, Min Yong, Cho, Nam Jun, Kim, Jong Deog
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Accumulation Adipocytes Adipogenesis Adipogenesis - drug effects AKT1 protein Angiogenesis Animals Anthocyanins Anthocyanins - isolation & purification Anthocyanins - pharmacology Antiangiogenics Antineoplastic agents Biology and Life Sciences Biotechnology Cancer Cornus - chemistry Cornus kousa Diabetes Down-Regulation - drug effects Ethanol Fatty acids Food Functional foods Functional foods & nutraceuticals Gene expression Genes Health aspects Herbal medicine High performance liquid chromatography Human Umbilical Vein Endothelial Cells Humans Kinases Leaves Lipids Lipogenesis Lipogenesis - drug effects Liquid chromatography Medicine and Health Sciences Metabolic disorders Metastasis Mice Natural products NIH 3T3 Cells Obesity Obesity - drug therapy Physiology Phytochemicals Plant cells Plant extracts Plant Extracts - isolation & purification Plant Extracts - pharmacology Preadipocytes Proteins Research and analysis methods Signaling Weight control Western blotting
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