Sulfated archaeol glycolipids: Comparison with other immunological adjuvants in mice

Archaeosomes are liposomes traditionally comprised of total polar lipids (TPL) or semi-synthetic glycerolipids of ether-linked isoprenoid phytanyl cores with varied glyco- and amino-head groups. As adjuvants, they induce robust, long-lasting humoral and cell-mediated immune responses and enhance pro...

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Veröffentlicht in:	PloS one 2018-12, Vol.13 (12), p.e0208067-e0208067
Hauptverfasser:	Akache, Bassel, Stark, Felicity C, Jia, Yimei, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A, Agbayani, Gerard, Williams, Dean, Jamshidi, Mohammad P, Krishnan, Lakshmi, McCluskie, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvant drugs Adjuvants Adjuvants, Immunologic Albumin Aluminum Aluminum compounds Aluminum hydroxide Animal models Animals Antigens Biochemistry Biology and Life Sciences Cancer Cancer prevention CD8 antigen CD8-Positive T-Lymphocytes - drug effects CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Cell-mediated immunity Chemical properties Chemokines Communicable diseases Councils Cytokines Cytokines - immunology Cytokines - metabolism Disaccharides Emulsions Female Formulations Glyceryl Ethers - administration & dosage Glyceryl Ethers - chemistry Glyceryl Ethers - immunology Glycolipid composition Glycolipids Glycolipids - administration & dosage Glycolipids - chemistry Glycolipids - immunology Granulocyte colony-stimulating factor Halobacterium salinarum - chemistry Hepatitis Hepatitis B Hepatitis B surface antigen Hepatitis B Surface Antigens - administration & dosage Hepatitis B Surface Antigens - immunology Hydroxides Immune response Immune response (cell-mediated) Immune response (humoral) Immunity Immunity, Cellular - drug effects Immunization Immunogenicity, Vaccine Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - immunology Immunology Immunostimulation Infectious diseases Interleukin 6 Lipids Liposomes Liposomes - administration & dosage Liposomes - chemistry Liposomes - immunology Lymphocytes Lymphocytes T Medicine and Health Sciences Membrane lipids Mice Mice, Inbred BALB C Mice, Inbred C57BL Models, Animal Older people Ovalbumin People and Places Phospholipids Plant lipids Research and Analysis Methods Serologic Tests Sulfates T cells Tumors Vaccines Vaccines - administration & dosage Vaccines - chemistry Vaccines - immunology
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