Examining the role of the surfactant family member SFTA3 in interneuron specification

The transcription factor NKX2.1, expressed at high levels in the medial ganglionic eminence (MGE), is a master regulator of cortical interneuron progenitor development. To identify gene candidates with expression profiles similar to NKX2.1, previous transcriptome analysis of human embryonic stem cel...

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Veröffentlicht in:	PloS one 2018-11, Vol.13 (11), p.e0198703
Hauptverfasser:	Chen, Christopher Y, Anderson, Nickesha C, Becker, Sandy, Schicht, Martin, Stoddard, Christopher, Bräuer, Lars, Paulsen, Friedrich, Grabel, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology Biology and Life Sciences Brain Brain - cytology Brain - embryology Brain - metabolism Cell Line Cell Lineage - genetics Clonal deletion Clustered Regularly Interspaced Short Palindromic Repeats Customization Embryogenesis Embryonic growth stage Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Gene expression Genes Humans Hypothyroidism Interneurons - cytology Interneurons - metabolism Lipids Lungs Mutation Neurogenesis - physiology Neurosciences Physical Sciences Proteins Pulmonary Surfactant-Associated Proteins - genetics Pulmonary Surfactant-Associated Proteins - metabolism Specifications Stem cells Surfactants Thyroid gland Thyroid transcription factor 1
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