Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder
The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD). Previous structural neuroimaging studies have found global volumetric and morphological abnormalities in the amygdala in...
Gespeichert in:
| Veröffentlicht in: | PloS one 2018-11, Vol.13 (11), p.e0207163-e0207163 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0207163 |
|---|---|
| container_issue | 11 |
| container_start_page | e0207163 |
| container_title | PloS one |
| container_volume | 13 |
| creator | Asami, Takeshi Nakamura, Ryota Takaishi, Masao Yoshida, Haruhisa Yoshimi, Asuka Whitford, Thomas J Hirayasu, Yoshio |
| description | The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD). Previous structural neuroimaging studies have found global volumetric and morphological abnormalities in the amygdala in patients with PD. Very few studies, however, have explored for structural abnormalities in various amygdala sub-regions, which consist of various sub-nuclei, each with different functions. This study aimed to evaluate for volumetric abnormalities in the amygdala sub-nuclei, in order to provide a better understanding neurobiological basis of PD. Thirty-eight patients with PD and 38 matched healthy control (HC) participants underwent structural MRI scanning. The volume of the whole amygdala, as well as its consistent sub-nuclei, were calculated using FreeSurfer software. Relative volumes of these amygdala sub-regions were compared between the two groups. Results showed significantly smaller volumes in the right lateral and basal nuclei in the patients with PD compared with the HC. Lateral and basal nuclei are thought to play crucial role for processing sensory information related with anxiety and fear. Our results suggest that these particular amygdala sub-regions play a role in the development of PD symptoms. |
| doi_str_mv | 10.1371/journal.pone.0207163 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_plos_</sourceid><recordid>TN_cdi_plos_journals_2130794269</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_a62ba79278124eef8f6f51b272402837</doaj_id><sourcerecordid>2131242686</sourcerecordid><originalsourceid>FETCH-LOGICAL-c526t-1ea36f2009f3985f0c98d11f64ef5092ea5d6a9f0dd12e1e8fbe6f308797ef813</originalsourceid><addsrcrecordid>eNptUk1v1DAQjRCIlsI_QBCJC5dd_JHY8QUJVXxUqsQBOFuTeLzrlWMvdlLUf493N61axMnjmTdv5o1eVb2mZE25pB92cU4B_HofA64JI5IK_qQ6p4qzlWCEP30Qn1Uvct4R0vJOiOfVGScN4bKR55X-MYL3mOqb6OcRc-1CPW2x9jBhAl9DMHUPuURhHjy6OtpjHcbbjQEPB_weJodhyvUfN23LL7ihNi7HZDC9rJ5Z8BlfLe9F9evL55-X31bX379eXX66Xg0tE9OKInBhGSHKctW1lgyqM5Ra0aBtiWIIrRGgLDGGMqTY2R6F5aSTSqLtKL-o3p549z5mvdwma0Y5kaphQhXE1QlhIuz0PrkR0q2O4PQxEdNGQ5pcEalBsB6kYrKjrMHCb4Vtac8kawjruCxcH5dpcz-iGYr6cqxHpI8rwW31Jt5owcpGrSgE7xeCFH_PmCc9ujyg9xAwzse9y2gmugP03T_Q_6trTqghxZwT2vtlKNEHv9x16YNf9OKX0vbmoZD7pjuD8L8ybr5C</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2130794269</pqid></control><display><type>article</type><title>Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Public Library of Science (PLoS)</source><creator>Asami, Takeshi ; Nakamura, Ryota ; Takaishi, Masao ; Yoshida, Haruhisa ; Yoshimi, Asuka ; Whitford, Thomas J ; Hirayasu, Yoshio</creator><creatorcontrib>Asami, Takeshi ; Nakamura, Ryota ; Takaishi, Masao ; Yoshida, Haruhisa ; Yoshimi, Asuka ; Whitford, Thomas J ; Hirayasu, Yoshio</creatorcontrib><description>The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD). Previous structural neuroimaging studies have found global volumetric and morphological abnormalities in the amygdala in patients with PD. Very few studies, however, have explored for structural abnormalities in various amygdala sub-regions, which consist of various sub-nuclei, each with different functions. This study aimed to evaluate for volumetric abnormalities in the amygdala sub-nuclei, in order to provide a better understanding neurobiological basis of PD. Thirty-eight patients with PD and 38 matched healthy control (HC) participants underwent structural MRI scanning. The volume of the whole amygdala, as well as its consistent sub-nuclei, were calculated using FreeSurfer software. Relative volumes of these amygdala sub-regions were compared between the two groups. Results showed significantly smaller volumes in the right lateral and basal nuclei in the patients with PD compared with the HC. Lateral and basal nuclei are thought to play crucial role for processing sensory information related with anxiety and fear. Our results suggest that these particular amygdala sub-regions play a role in the development of PD symptoms.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0207163</identifier><identifier>PMID: 30403747</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abnormalities ; Adult ; Amygdala ; Amygdala - diagnostic imaging ; Amygdala - pathology ; Anxiety ; Basolateral Nuclear Complex - diagnostic imaging ; Basolateral Nuclear Complex - pathology ; Biology and Life Sciences ; Case-Control Studies ; Fear ; Female ; Humans ; Imaging, Three-Dimensional ; Information processing ; Magnetic Resonance Imaging ; Male ; Medical imaging ; Medicine and Health Sciences ; Middle Aged ; Neuroimaging ; Neurology ; NMR ; Nuclear magnetic resonance ; Nuclei ; Organ Size ; Panic attacks ; Panic Disorder - diagnostic imaging ; Panic Disorder - pathology ; Patients ; Research and Analysis Methods ; Sensory integration ; Social Sciences ; Young Adult</subject><ispartof>PloS one, 2018-11, Vol.13 (11), p.e0207163-e0207163</ispartof><rights>2018 Asami et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2018 Asami et al 2018 Asami et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c526t-1ea36f2009f3985f0c98d11f64ef5092ea5d6a9f0dd12e1e8fbe6f308797ef813</citedby><cites>FETCH-LOGICAL-c526t-1ea36f2009f3985f0c98d11f64ef5092ea5d6a9f0dd12e1e8fbe6f308797ef813</cites><orcidid>0000-0003-1803-413X ; 0000-0003-3089-3578</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221356/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221356/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79569,79570</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30403747$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Asami, Takeshi</creatorcontrib><creatorcontrib>Nakamura, Ryota</creatorcontrib><creatorcontrib>Takaishi, Masao</creatorcontrib><creatorcontrib>Yoshida, Haruhisa</creatorcontrib><creatorcontrib>Yoshimi, Asuka</creatorcontrib><creatorcontrib>Whitford, Thomas J</creatorcontrib><creatorcontrib>Hirayasu, Yoshio</creatorcontrib><title>Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD). Previous structural neuroimaging studies have found global volumetric and morphological abnormalities in the amygdala in patients with PD. Very few studies, however, have explored for structural abnormalities in various amygdala sub-regions, which consist of various sub-nuclei, each with different functions. This study aimed to evaluate for volumetric abnormalities in the amygdala sub-nuclei, in order to provide a better understanding neurobiological basis of PD. Thirty-eight patients with PD and 38 matched healthy control (HC) participants underwent structural MRI scanning. The volume of the whole amygdala, as well as its consistent sub-nuclei, were calculated using FreeSurfer software. Relative volumes of these amygdala sub-regions were compared between the two groups. Results showed significantly smaller volumes in the right lateral and basal nuclei in the patients with PD compared with the HC. Lateral and basal nuclei are thought to play crucial role for processing sensory information related with anxiety and fear. Our results suggest that these particular amygdala sub-regions play a role in the development of PD symptoms.</description><subject>Abnormalities</subject><subject>Adult</subject><subject>Amygdala</subject><subject>Amygdala - diagnostic imaging</subject><subject>Amygdala - pathology</subject><subject>Anxiety</subject><subject>Basolateral Nuclear Complex - diagnostic imaging</subject><subject>Basolateral Nuclear Complex - pathology</subject><subject>Biology and Life Sciences</subject><subject>Case-Control Studies</subject><subject>Fear</subject><subject>Female</subject><subject>Humans</subject><subject>Imaging, Three-Dimensional</subject><subject>Information processing</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Neuroimaging</subject><subject>Neurology</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Nuclei</subject><subject>Organ Size</subject><subject>Panic attacks</subject><subject>Panic Disorder - diagnostic imaging</subject><subject>Panic Disorder - pathology</subject><subject>Patients</subject><subject>Research and Analysis Methods</subject><subject>Sensory integration</subject><subject>Social Sciences</subject><subject>Young Adult</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNptUk1v1DAQjRCIlsI_QBCJC5dd_JHY8QUJVXxUqsQBOFuTeLzrlWMvdlLUf493N61axMnjmTdv5o1eVb2mZE25pB92cU4B_HofA64JI5IK_qQ6p4qzlWCEP30Qn1Uvct4R0vJOiOfVGScN4bKR55X-MYL3mOqb6OcRc-1CPW2x9jBhAl9DMHUPuURhHjy6OtpjHcbbjQEPB_weJodhyvUfN23LL7ihNi7HZDC9rJ5Z8BlfLe9F9evL55-X31bX379eXX66Xg0tE9OKInBhGSHKctW1lgyqM5Ra0aBtiWIIrRGgLDGGMqTY2R6F5aSTSqLtKL-o3p549z5mvdwma0Y5kaphQhXE1QlhIuz0PrkR0q2O4PQxEdNGQ5pcEalBsB6kYrKjrMHCb4Vtac8kawjruCxcH5dpcz-iGYr6cqxHpI8rwW31Jt5owcpGrSgE7xeCFH_PmCc9ujyg9xAwzse9y2gmugP03T_Q_6trTqghxZwT2vtlKNEHv9x16YNf9OKX0vbmoZD7pjuD8L8ybr5C</recordid><startdate>20181107</startdate><enddate>20181107</enddate><creator>Asami, Takeshi</creator><creator>Nakamura, Ryota</creator><creator>Takaishi, Masao</creator><creator>Yoshida, Haruhisa</creator><creator>Yoshimi, Asuka</creator><creator>Whitford, Thomas J</creator><creator>Hirayasu, Yoshio</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-1803-413X</orcidid><orcidid>https://orcid.org/0000-0003-3089-3578</orcidid></search><sort><creationdate>20181107</creationdate><title>Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder</title><author>Asami, Takeshi ; Nakamura, Ryota ; Takaishi, Masao ; Yoshida, Haruhisa ; Yoshimi, Asuka ; Whitford, Thomas J ; Hirayasu, Yoshio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c526t-1ea36f2009f3985f0c98d11f64ef5092ea5d6a9f0dd12e1e8fbe6f308797ef813</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Abnormalities</topic><topic>Adult</topic><topic>Amygdala</topic><topic>Amygdala - diagnostic imaging</topic><topic>Amygdala - pathology</topic><topic>Anxiety</topic><topic>Basolateral Nuclear Complex - diagnostic imaging</topic><topic>Basolateral Nuclear Complex - pathology</topic><topic>Biology and Life Sciences</topic><topic>Case-Control Studies</topic><topic>Fear</topic><topic>Female</topic><topic>Humans</topic><topic>Imaging, Three-Dimensional</topic><topic>Information processing</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Neuroimaging</topic><topic>Neurology</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Nuclei</topic><topic>Organ Size</topic><topic>Panic attacks</topic><topic>Panic Disorder - diagnostic imaging</topic><topic>Panic Disorder - pathology</topic><topic>Patients</topic><topic>Research and Analysis Methods</topic><topic>Sensory integration</topic><topic>Social Sciences</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asami, Takeshi</creatorcontrib><creatorcontrib>Nakamura, Ryota</creatorcontrib><creatorcontrib>Takaishi, Masao</creatorcontrib><creatorcontrib>Yoshida, Haruhisa</creatorcontrib><creatorcontrib>Yoshimi, Asuka</creatorcontrib><creatorcontrib>Whitford, Thomas J</creatorcontrib><creatorcontrib>Hirayasu, Yoshio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asami, Takeshi</au><au>Nakamura, Ryota</au><au>Takaishi, Masao</au><au>Yoshida, Haruhisa</au><au>Yoshimi, Asuka</au><au>Whitford, Thomas J</au><au>Hirayasu, Yoshio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2018-11-07</date><risdate>2018</risdate><volume>13</volume><issue>11</issue><spage>e0207163</spage><epage>e0207163</epage><pages>e0207163-e0207163</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD). Previous structural neuroimaging studies have found global volumetric and morphological abnormalities in the amygdala in patients with PD. Very few studies, however, have explored for structural abnormalities in various amygdala sub-regions, which consist of various sub-nuclei, each with different functions. This study aimed to evaluate for volumetric abnormalities in the amygdala sub-nuclei, in order to provide a better understanding neurobiological basis of PD. Thirty-eight patients with PD and 38 matched healthy control (HC) participants underwent structural MRI scanning. The volume of the whole amygdala, as well as its consistent sub-nuclei, were calculated using FreeSurfer software. Relative volumes of these amygdala sub-regions were compared between the two groups. Results showed significantly smaller volumes in the right lateral and basal nuclei in the patients with PD compared with the HC. Lateral and basal nuclei are thought to play crucial role for processing sensory information related with anxiety and fear. Our results suggest that these particular amygdala sub-regions play a role in the development of PD symptoms.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>30403747</pmid><doi>10.1371/journal.pone.0207163</doi><orcidid>https://orcid.org/0000-0003-1803-413X</orcidid><orcidid>https://orcid.org/0000-0003-3089-3578</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2018-11, Vol.13 (11), p.e0207163-e0207163 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2130794269 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Abnormalities Adult Amygdala Amygdala - diagnostic imaging Amygdala - pathology Anxiety Basolateral Nuclear Complex - diagnostic imaging Basolateral Nuclear Complex - pathology Biology and Life Sciences Case-Control Studies Fear Female Humans Imaging, Three-Dimensional Information processing Magnetic Resonance Imaging Male Medical imaging Medicine and Health Sciences Middle Aged Neuroimaging Neurology NMR Nuclear magnetic resonance Nuclei Organ Size Panic attacks Panic Disorder - diagnostic imaging Panic Disorder - pathology Patients Research and Analysis Methods Sensory integration Social Sciences Young Adult |
| title | Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T03%3A50%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Smaller%20volumes%20in%20the%20lateral%20and%20basal%20nuclei%20of%20the%20amygdala%20in%20patients%20with%20panic%20disorder&rft.jtitle=PloS%20one&rft.au=Asami,%20Takeshi&rft.date=2018-11-07&rft.volume=13&rft.issue=11&rft.spage=e0207163&rft.epage=e0207163&rft.pages=e0207163-e0207163&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0207163&rft_dat=%3Cproquest_plos_%3E2131242686%3C/proquest_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2130794269&rft_id=info:pmid/30403747&rft_doaj_id=oai_doaj_org_article_a62ba79278124eef8f6f51b272402837&rfr_iscdi=true |