Increased presepsin levels are associated with the severity of fungal bloodstream infections

Presepsin is a widely recognized biomarker for sepsis. However, little is known about the usefulness of presepsin in invasive fungal infection. The aim of this study was to determine the plasma levels of presepsin in fungal bloodstream infections and to investigate whether it reflects the disease se...

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Veröffentlicht in:	PloS one 2018-10, Vol.13 (10), p.e0206089-e0206089
Hauptverfasser:	Bamba, Yuuki, Moro, Hiroshi, Aoki, Nobumasa, Koizumi, Takeshi, Ohshima, Yasuyoshi, Watanabe, Satoshi, Sakagami, Takuro, Koya, Toshiyuki, Takada, Toshinori, Kikuchi, Toshiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Bacterial diseases Bacterial infections Biology and Life Sciences Biomarkers Biomarkers - blood Blood Blood cells C-reactive protein C-Reactive Protein - metabolism Candida albicans Candida albicans - physiology E coli Epidemiology Escherichia coli Escherichia coli - physiology Family medical history Female Fungal infections Fungemia Fungi Hospitals Humans Immunoassay Incubation Infections Infectious diseases Intensive care Laboratories Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - microbiology Lipopolysaccharide Receptors - blood Lipopolysaccharides Lipopolysaccharides - adverse effects Male Measurement methods Medical diagnosis Medicine Medicine and Health Sciences Meta-analysis Middle Aged Mortality Mycoses - blood Neutropenia Patients Peptide Fragments - blood Plasma levels Procalcitonin Procalcitonin - blood Prospective Studies Proteins Research and Analysis Methods Sepsis Sepsis - blood Severity of Illness Index Statistical analysis Statistical methods Studies University graduates Up-Regulation
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