Bioprocess development of antibody-drug conjugate production for cancer treatment

Antibody-drug conjugate (ADC) is a class of targeted cancer therapies that combine the advantages of monoclonal antibody (mAb)'s specific targeting and chemotherapy's potent cytotoxicity. The therapeutic effect of ADC is significantly affected by its bioproduction process. This study aims...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2018-10, Vol.13 (10), p.e0206246
Hauptverfasser:	Ou, Jianfa, Si, Yingnan, Goh, KahYong, Yasui, Norio, Guo, Yichen, Song, Jiajia, Wang, Lizhong, Jaskula-Sztul, Renata, Fan, Jinda, Zhou, Lufang, Liu, Runhua, Liu, Xiaoguang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody-drug conjugates Antigens Batch culture Biology and Life Sciences Biomedical engineering Breast cancer Cancer Cancer therapies Cell culture Chemotherapy Complications and side effects Confocal microscopy Conjugates Conjugation Cytotoxicity Dosage and administration Engineering ErbB-2 protein Flow cytometry Gel electrophoresis Glucose Health aspects Lymphoma Medicine and Health Sciences Methods Microscopy Molecular structure Monoclonal antibodies Physiological aspects Process controls Research and analysis methods Sodium lauryl sulfate Toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!