Trans-allelic mutational effects at the Peg3 imprinted locus

How one allele interacts with the other for the function of a gene is not well understood. In this study, we tested potential allelic interaction at the Peg3 imprinted locus with several mutant alleles targeting an Imprinting Control Region, the Peg3-DMR. According to the results, maternal deletion...

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Veröffentlicht in:	PloS one 2018-10, Vol.13 (10), p.e0206112-e0206112
Hauptverfasser:	Bretz, Corey L, Kim, Joomyeong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biology and Life Sciences Chromosomes Deoxyribonucleic acid Developmental stages DNA DNA methylation Epigenetics Gene expression Gene mutation Genetic aspects Genomes Genomic imprinting Imprinting Loci Newborn babies Peg3 protein Physiological aspects Proteins Quantitative genetics
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