Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS
Adolescent girls and young women (AGYW) bear the brunt of the HIV epidemic in South Africa. 'DREAMS' aims to reduce HIV incidence through multi-level combination prevention. We describe HIV incidence and uptake of HIV and sexual reproductive health (SRH) by AGYW in KwaZulu-Natal (KZN), pri...
Gespeichert in:
| Veröffentlicht in: | PloS one 2018-10, Vol.13 (10), p.e0203193-e0203193 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0203193 |
|---|---|
| container_issue | 10 |
| container_start_page | e0203193 |
| container_title | PloS one |
| container_volume | 13 |
| creator | Chimbindi, Natsayi Mthiyane, Nondumiso Birdthistle, Isolde Floyd, Sian McGrath, Nuala Pillay, Deenan Seeley, Janet Zuma, Thembelihle Dreyer, Jaco Gareta, Dickman Mutevedzi, Tinofa Fenty, Justin Herbst, Kobus Smit, Theresa Baisley, Kathy Shahmanesh, Maryam |
| description | Adolescent girls and young women (AGYW) bear the brunt of the HIV epidemic in South Africa. 'DREAMS' aims to reduce HIV incidence through multi-level combination prevention. We describe HIV incidence and uptake of HIV and sexual reproductive health (SRH) by AGYW in KwaZulu-Natal (KZN), prior to DREAMS.
Longitudinal and cross-sectional analysis of women (15-24 year old) in a population-based HIV incidence cohort within a demographic surveillance site in KZN. Observation time for HIV incidence was person-years at risk while resident. "Current use of contraceptives" and "having an HIV test in the past 12 months" was compared between 2011 and 2015.
In 2015, HIV prevalence was 11.0% and 34.1% and HIV incidence (2011-2015) was 4.54% (95%CI:3.89-5.30) and 7.45% (95%CI:6.51-8.51) per year in 15-19 and 20-24 year olds respectively, with no significant decline compared to 2006-2010. In 2015, 90.7% of 20-24-year-olds were unemployed, 36.4% and 51.7% of 15-19 and 20-24 year olds reported recent migration; 20.9% and 72.6% of 15-19 and 20-24 year olds had ever been pregnant. In 2015, less than 50% reported condom-use at last sex, 15.0% of 15-19 year olds and 48.9% of 20-24 year olds were currently using contraception and 32.0% and 66.7% of 15-19 and 20-24 year olds had tested for HIV in the past 12 months. There had been no improvement compared to 2011. Factors associated with AGYW testing for HIV in the past 12 months were, survey year-2011 more likely than 2015 (aOR = 0.50), number of partners (aOR = 3.25), ever been pregnant (aOR = 2.47) and knowing where to find ART (aOR = 1.54). Factors associated with contraception use were being older (aOR = 4.83); ever been pregnant (aOR = 12.62); knowing where to get ART (aOR = 1.79) and having had an HIV test in past 12 months (aOR = 1.74).
Prior to DREAMS, HIV incidence in AGYW was high. HIV and SRH service uptake did not improve and was suboptimal. Findings highlight the need for combination HIV prevention programmes for AGYW in this economically vulnerable area. |
| doi_str_mv | 10.1371/journal.pone.0203193 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2120712110</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A559617723</galeid><doaj_id>oai_doaj_org_article_c7da71b1b15140169d42fa03b29d59a8</doaj_id><sourcerecordid>A559617723</sourcerecordid><originalsourceid>FETCH-LOGICAL-c585t-8ed8d5bb01264a89425f8fe59996ea6a1c7e8960d598346d8dd4e990e564cb483</originalsourceid><addsrcrecordid>eNptkt9u0zAUxiMEYmPwBggsISEuaLHj2IlvkKoxWMX4IwZccGOdJE7qzrWLnWzqc_DCOG02tQhFchL7d75zzueTJE8JnhKakzdL13sLZrp2Vk1xiikR9F5yHNd0wuPv_b3vo-RRCEuMGS04f5gcUUxTFg-Pkz9flQ86dMp2ZoMWul0gbStdK1sp5Bp0Pv-JwNZo7ZxHQflrHff7dQdXKoIIamdUqGI0arU3YctuXG9bdONWyg6M7z0Y9PEGfvWmn3yGDsxrdOn6boFmjdcVoLXXUb1z6N23s9mny8fJgwZMUE_G90ny4_3Z99PzycWXD_PT2cWkYgXrJoWqi5qVJSYpz6AQWcqaolFMCMEVcCBVrgrBcc1EQTMe4TpTQmDFeFaVWUFPkuc73bVxQY5-BpmSFOckJQRHYr4jagdLGctcgd9IB1puN5xvJfhOV0bJKq8hJ2V8GMkw4aLO0gYwLVMRC4Ah29sxW1-uVD14Fn05ED08sXohW3ctOREECxIFXo0C3v3uVejkSkfrjQGrXL-tm2TxUimP6It_0P93N1ItxAa0bVzMWw2icsaY4CTPUxqpl3vUQoHpFsGZvtPOhkMw24GVdyF41dz1RrAcRva2CDmMrBxHNoY92_flLuh2Rulf8mvoYQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2120712110</pqid></control><display><type>article</type><title>Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS</title><source>Public Library of Science (PLoS) Journals Open Access</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Chimbindi, Natsayi ; Mthiyane, Nondumiso ; Birdthistle, Isolde ; Floyd, Sian ; McGrath, Nuala ; Pillay, Deenan ; Seeley, Janet ; Zuma, Thembelihle ; Dreyer, Jaco ; Gareta, Dickman ; Mutevedzi, Tinofa ; Fenty, Justin ; Herbst, Kobus ; Smit, Theresa ; Baisley, Kathy ; Shahmanesh, Maryam</creator><creatorcontrib>Chimbindi, Natsayi ; Mthiyane, Nondumiso ; Birdthistle, Isolde ; Floyd, Sian ; McGrath, Nuala ; Pillay, Deenan ; Seeley, Janet ; Zuma, Thembelihle ; Dreyer, Jaco ; Gareta, Dickman ; Mutevedzi, Tinofa ; Fenty, Justin ; Herbst, Kobus ; Smit, Theresa ; Baisley, Kathy ; Shahmanesh, Maryam</creatorcontrib><description>Adolescent girls and young women (AGYW) bear the brunt of the HIV epidemic in South Africa. 'DREAMS' aims to reduce HIV incidence through multi-level combination prevention. We describe HIV incidence and uptake of HIV and sexual reproductive health (SRH) by AGYW in KwaZulu-Natal (KZN), prior to DREAMS.
Longitudinal and cross-sectional analysis of women (15-24 year old) in a population-based HIV incidence cohort within a demographic surveillance site in KZN. Observation time for HIV incidence was person-years at risk while resident. "Current use of contraceptives" and "having an HIV test in the past 12 months" was compared between 2011 and 2015.
In 2015, HIV prevalence was 11.0% and 34.1% and HIV incidence (2011-2015) was 4.54% (95%CI:3.89-5.30) and 7.45% (95%CI:6.51-8.51) per year in 15-19 and 20-24 year olds respectively, with no significant decline compared to 2006-2010. In 2015, 90.7% of 20-24-year-olds were unemployed, 36.4% and 51.7% of 15-19 and 20-24 year olds reported recent migration; 20.9% and 72.6% of 15-19 and 20-24 year olds had ever been pregnant. In 2015, less than 50% reported condom-use at last sex, 15.0% of 15-19 year olds and 48.9% of 20-24 year olds were currently using contraception and 32.0% and 66.7% of 15-19 and 20-24 year olds had tested for HIV in the past 12 months. There had been no improvement compared to 2011. Factors associated with AGYW testing for HIV in the past 12 months were, survey year-2011 more likely than 2015 (aOR = 0.50), number of partners (aOR = 3.25), ever been pregnant (aOR = 2.47) and knowing where to find ART (aOR = 1.54). Factors associated with contraception use were being older (aOR = 4.83); ever been pregnant (aOR = 12.62); knowing where to get ART (aOR = 1.79) and having had an HIV test in past 12 months (aOR = 1.74).
Prior to DREAMS, HIV incidence in AGYW was high. HIV and SRH service uptake did not improve and was suboptimal. Findings highlight the need for combination HIV prevention programmes for AGYW in this economically vulnerable area.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0203193</identifier><identifier>PMID: 30325932</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acquired immune deficiency syndrome ; Adolescent ; Adult ; AIDS ; Antiretroviral agents ; Antiretroviral therapy ; Biology and Life Sciences ; Contraception ; Contraceptives ; Demographics ; Disease prevention ; Dosage and administration ; Drug therapy ; Epidemics ; Female ; Gender differences ; Girls ; Health aspects ; Health care ; Health risks ; Health services ; HIV ; HIV - pathogenicity ; HIV infections ; HIV Infections - drug therapy ; HIV Infections - epidemiology ; HIV Infections - pathology ; HIV Infections - virology ; HIV tests ; Households ; Human immunodeficiency virus ; Humans ; Hygiene ; Incidence ; Information systems ; Male ; Medical research ; Medical tests ; Medicine ; Medicine and Health Sciences ; Migration ; Patient satisfaction ; People and Places ; Planning ; Population ; Pregnancy ; Prevention ; Reproductive health ; Risk Factors ; Rural areas ; Rural Population ; Sexual Behavior ; Sexual Partners ; Sexually transmitted diseases ; Social aspects ; South Africa - epidemiology ; STD ; Teenage girls ; Teenagers ; Wellness programs ; Womens health ; Young Adult ; Young adults</subject><ispartof>PloS one, 2018-10, Vol.13 (10), p.e0203193-e0203193</ispartof><rights>COPYRIGHT 2018 Public Library of Science</rights><rights>2018 Chimbindi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2018 Chimbindi et al 2018 Chimbindi et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c585t-8ed8d5bb01264a89425f8fe59996ea6a1c7e8960d598346d8dd4e990e564cb483</citedby><cites>FETCH-LOGICAL-c585t-8ed8d5bb01264a89425f8fe59996ea6a1c7e8960d598346d8dd4e990e564cb483</cites><orcidid>0000-0001-7129-8535</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191091/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191091/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79569,79570</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30325932$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chimbindi, Natsayi</creatorcontrib><creatorcontrib>Mthiyane, Nondumiso</creatorcontrib><creatorcontrib>Birdthistle, Isolde</creatorcontrib><creatorcontrib>Floyd, Sian</creatorcontrib><creatorcontrib>McGrath, Nuala</creatorcontrib><creatorcontrib>Pillay, Deenan</creatorcontrib><creatorcontrib>Seeley, Janet</creatorcontrib><creatorcontrib>Zuma, Thembelihle</creatorcontrib><creatorcontrib>Dreyer, Jaco</creatorcontrib><creatorcontrib>Gareta, Dickman</creatorcontrib><creatorcontrib>Mutevedzi, Tinofa</creatorcontrib><creatorcontrib>Fenty, Justin</creatorcontrib><creatorcontrib>Herbst, Kobus</creatorcontrib><creatorcontrib>Smit, Theresa</creatorcontrib><creatorcontrib>Baisley, Kathy</creatorcontrib><creatorcontrib>Shahmanesh, Maryam</creatorcontrib><title>Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Adolescent girls and young women (AGYW) bear the brunt of the HIV epidemic in South Africa. 'DREAMS' aims to reduce HIV incidence through multi-level combination prevention. We describe HIV incidence and uptake of HIV and sexual reproductive health (SRH) by AGYW in KwaZulu-Natal (KZN), prior to DREAMS.
Longitudinal and cross-sectional analysis of women (15-24 year old) in a population-based HIV incidence cohort within a demographic surveillance site in KZN. Observation time for HIV incidence was person-years at risk while resident. "Current use of contraceptives" and "having an HIV test in the past 12 months" was compared between 2011 and 2015.
In 2015, HIV prevalence was 11.0% and 34.1% and HIV incidence (2011-2015) was 4.54% (95%CI:3.89-5.30) and 7.45% (95%CI:6.51-8.51) per year in 15-19 and 20-24 year olds respectively, with no significant decline compared to 2006-2010. In 2015, 90.7% of 20-24-year-olds were unemployed, 36.4% and 51.7% of 15-19 and 20-24 year olds reported recent migration; 20.9% and 72.6% of 15-19 and 20-24 year olds had ever been pregnant. In 2015, less than 50% reported condom-use at last sex, 15.0% of 15-19 year olds and 48.9% of 20-24 year olds were currently using contraception and 32.0% and 66.7% of 15-19 and 20-24 year olds had tested for HIV in the past 12 months. There had been no improvement compared to 2011. Factors associated with AGYW testing for HIV in the past 12 months were, survey year-2011 more likely than 2015 (aOR = 0.50), number of partners (aOR = 3.25), ever been pregnant (aOR = 2.47) and knowing where to find ART (aOR = 1.54). Factors associated with contraception use were being older (aOR = 4.83); ever been pregnant (aOR = 12.62); knowing where to get ART (aOR = 1.79) and having had an HIV test in past 12 months (aOR = 1.74).
Prior to DREAMS, HIV incidence in AGYW was high. HIV and SRH service uptake did not improve and was suboptimal. Findings highlight the need for combination HIV prevention programmes for AGYW in this economically vulnerable area.</description><subject>Acquired immune deficiency syndrome</subject><subject>Adolescent</subject><subject>Adult</subject><subject>AIDS</subject><subject>Antiretroviral agents</subject><subject>Antiretroviral therapy</subject><subject>Biology and Life Sciences</subject><subject>Contraception</subject><subject>Contraceptives</subject><subject>Demographics</subject><subject>Disease prevention</subject><subject>Dosage and administration</subject><subject>Drug therapy</subject><subject>Epidemics</subject><subject>Female</subject><subject>Gender differences</subject><subject>Girls</subject><subject>Health aspects</subject><subject>Health care</subject><subject>Health risks</subject><subject>Health services</subject><subject>HIV</subject><subject>HIV - pathogenicity</subject><subject>HIV infections</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - epidemiology</subject><subject>HIV Infections - pathology</subject><subject>HIV Infections - virology</subject><subject>HIV tests</subject><subject>Households</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Hygiene</subject><subject>Incidence</subject><subject>Information systems</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical tests</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Migration</subject><subject>Patient satisfaction</subject><subject>People and Places</subject><subject>Planning</subject><subject>Population</subject><subject>Pregnancy</subject><subject>Prevention</subject><subject>Reproductive health</subject><subject>Risk Factors</subject><subject>Rural areas</subject><subject>Rural Population</subject><subject>Sexual Behavior</subject><subject>Sexual Partners</subject><subject>Sexually transmitted diseases</subject><subject>Social aspects</subject><subject>South Africa - epidemiology</subject><subject>STD</subject><subject>Teenage girls</subject><subject>Teenagers</subject><subject>Wellness programs</subject><subject>Womens health</subject><subject>Young Adult</subject><subject>Young adults</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNptkt9u0zAUxiMEYmPwBggsISEuaLHj2IlvkKoxWMX4IwZccGOdJE7qzrWLnWzqc_DCOG02tQhFchL7d75zzueTJE8JnhKakzdL13sLZrp2Vk1xiikR9F5yHNd0wuPv_b3vo-RRCEuMGS04f5gcUUxTFg-Pkz9flQ86dMp2ZoMWul0gbStdK1sp5Bp0Pv-JwNZo7ZxHQflrHff7dQdXKoIIamdUqGI0arU3YctuXG9bdONWyg6M7z0Y9PEGfvWmn3yGDsxrdOn6boFmjdcVoLXXUb1z6N23s9mny8fJgwZMUE_G90ny4_3Z99PzycWXD_PT2cWkYgXrJoWqi5qVJSYpz6AQWcqaolFMCMEVcCBVrgrBcc1EQTMe4TpTQmDFeFaVWUFPkuc73bVxQY5-BpmSFOckJQRHYr4jagdLGctcgd9IB1puN5xvJfhOV0bJKq8hJ2V8GMkw4aLO0gYwLVMRC4Ah29sxW1-uVD14Fn05ED08sXohW3ctOREECxIFXo0C3v3uVejkSkfrjQGrXL-tm2TxUimP6It_0P93N1ItxAa0bVzMWw2icsaY4CTPUxqpl3vUQoHpFsGZvtPOhkMw24GVdyF41dz1RrAcRva2CDmMrBxHNoY92_flLuh2Rulf8mvoYQ</recordid><startdate>20181016</startdate><enddate>20181016</enddate><creator>Chimbindi, Natsayi</creator><creator>Mthiyane, Nondumiso</creator><creator>Birdthistle, Isolde</creator><creator>Floyd, Sian</creator><creator>McGrath, Nuala</creator><creator>Pillay, Deenan</creator><creator>Seeley, Janet</creator><creator>Zuma, Thembelihle</creator><creator>Dreyer, Jaco</creator><creator>Gareta, Dickman</creator><creator>Mutevedzi, Tinofa</creator><creator>Fenty, Justin</creator><creator>Herbst, Kobus</creator><creator>Smit, Theresa</creator><creator>Baisley, Kathy</creator><creator>Shahmanesh, Maryam</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-7129-8535</orcidid></search><sort><creationdate>20181016</creationdate><title>Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS</title><author>Chimbindi, Natsayi ; Mthiyane, Nondumiso ; Birdthistle, Isolde ; Floyd, Sian ; McGrath, Nuala ; Pillay, Deenan ; Seeley, Janet ; Zuma, Thembelihle ; Dreyer, Jaco ; Gareta, Dickman ; Mutevedzi, Tinofa ; Fenty, Justin ; Herbst, Kobus ; Smit, Theresa ; Baisley, Kathy ; Shahmanesh, Maryam</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c585t-8ed8d5bb01264a89425f8fe59996ea6a1c7e8960d598346d8dd4e990e564cb483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>Adolescent</topic><topic>Adult</topic><topic>AIDS</topic><topic>Antiretroviral agents</topic><topic>Antiretroviral therapy</topic><topic>Biology and Life Sciences</topic><topic>Contraception</topic><topic>Contraceptives</topic><topic>Demographics</topic><topic>Disease prevention</topic><topic>Dosage and administration</topic><topic>Drug therapy</topic><topic>Epidemics</topic><topic>Female</topic><topic>Gender differences</topic><topic>Girls</topic><topic>Health aspects</topic><topic>Health care</topic><topic>Health risks</topic><topic>Health services</topic><topic>HIV</topic><topic>HIV - pathogenicity</topic><topic>HIV infections</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Infections - epidemiology</topic><topic>HIV Infections - pathology</topic><topic>HIV Infections - virology</topic><topic>HIV tests</topic><topic>Households</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Hygiene</topic><topic>Incidence</topic><topic>Information systems</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical tests</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Migration</topic><topic>Patient satisfaction</topic><topic>People and Places</topic><topic>Planning</topic><topic>Population</topic><topic>Pregnancy</topic><topic>Prevention</topic><topic>Reproductive health</topic><topic>Risk Factors</topic><topic>Rural areas</topic><topic>Rural Population</topic><topic>Sexual Behavior</topic><topic>Sexual Partners</topic><topic>Sexually transmitted diseases</topic><topic>Social aspects</topic><topic>South Africa - epidemiology</topic><topic>STD</topic><topic>Teenage girls</topic><topic>Teenagers</topic><topic>Wellness programs</topic><topic>Womens health</topic><topic>Young Adult</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chimbindi, Natsayi</creatorcontrib><creatorcontrib>Mthiyane, Nondumiso</creatorcontrib><creatorcontrib>Birdthistle, Isolde</creatorcontrib><creatorcontrib>Floyd, Sian</creatorcontrib><creatorcontrib>McGrath, Nuala</creatorcontrib><creatorcontrib>Pillay, Deenan</creatorcontrib><creatorcontrib>Seeley, Janet</creatorcontrib><creatorcontrib>Zuma, Thembelihle</creatorcontrib><creatorcontrib>Dreyer, Jaco</creatorcontrib><creatorcontrib>Gareta, Dickman</creatorcontrib><creatorcontrib>Mutevedzi, Tinofa</creatorcontrib><creatorcontrib>Fenty, Justin</creatorcontrib><creatorcontrib>Herbst, Kobus</creatorcontrib><creatorcontrib>Smit, Theresa</creatorcontrib><creatorcontrib>Baisley, Kathy</creatorcontrib><creatorcontrib>Shahmanesh, Maryam</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>Natural Science Collection (ProQuest)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chimbindi, Natsayi</au><au>Mthiyane, Nondumiso</au><au>Birdthistle, Isolde</au><au>Floyd, Sian</au><au>McGrath, Nuala</au><au>Pillay, Deenan</au><au>Seeley, Janet</au><au>Zuma, Thembelihle</au><au>Dreyer, Jaco</au><au>Gareta, Dickman</au><au>Mutevedzi, Tinofa</au><au>Fenty, Justin</au><au>Herbst, Kobus</au><au>Smit, Theresa</au><au>Baisley, Kathy</au><au>Shahmanesh, Maryam</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2018-10-16</date><risdate>2018</risdate><volume>13</volume><issue>10</issue><spage>e0203193</spage><epage>e0203193</epage><pages>e0203193-e0203193</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Adolescent girls and young women (AGYW) bear the brunt of the HIV epidemic in South Africa. 'DREAMS' aims to reduce HIV incidence through multi-level combination prevention. We describe HIV incidence and uptake of HIV and sexual reproductive health (SRH) by AGYW in KwaZulu-Natal (KZN), prior to DREAMS.
Longitudinal and cross-sectional analysis of women (15-24 year old) in a population-based HIV incidence cohort within a demographic surveillance site in KZN. Observation time for HIV incidence was person-years at risk while resident. "Current use of contraceptives" and "having an HIV test in the past 12 months" was compared between 2011 and 2015.
In 2015, HIV prevalence was 11.0% and 34.1% and HIV incidence (2011-2015) was 4.54% (95%CI:3.89-5.30) and 7.45% (95%CI:6.51-8.51) per year in 15-19 and 20-24 year olds respectively, with no significant decline compared to 2006-2010. In 2015, 90.7% of 20-24-year-olds were unemployed, 36.4% and 51.7% of 15-19 and 20-24 year olds reported recent migration; 20.9% and 72.6% of 15-19 and 20-24 year olds had ever been pregnant. In 2015, less than 50% reported condom-use at last sex, 15.0% of 15-19 year olds and 48.9% of 20-24 year olds were currently using contraception and 32.0% and 66.7% of 15-19 and 20-24 year olds had tested for HIV in the past 12 months. There had been no improvement compared to 2011. Factors associated with AGYW testing for HIV in the past 12 months were, survey year-2011 more likely than 2015 (aOR = 0.50), number of partners (aOR = 3.25), ever been pregnant (aOR = 2.47) and knowing where to find ART (aOR = 1.54). Factors associated with contraception use were being older (aOR = 4.83); ever been pregnant (aOR = 12.62); knowing where to get ART (aOR = 1.79) and having had an HIV test in past 12 months (aOR = 1.74).
Prior to DREAMS, HIV incidence in AGYW was high. HIV and SRH service uptake did not improve and was suboptimal. Findings highlight the need for combination HIV prevention programmes for AGYW in this economically vulnerable area.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>30325932</pmid><doi>10.1371/journal.pone.0203193</doi><orcidid>https://orcid.org/0000-0001-7129-8535</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2018-10, Vol.13 (10), p.e0203193-e0203193 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2120712110 |
| source | Public Library of Science (PLoS) Journals Open Access; MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Acquired immune deficiency syndrome Adolescent Adult AIDS Antiretroviral agents Antiretroviral therapy Biology and Life Sciences Contraception Contraceptives Demographics Disease prevention Dosage and administration Drug therapy Epidemics Female Gender differences Girls Health aspects Health care Health risks Health services HIV HIV - pathogenicity HIV infections HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - pathology HIV Infections - virology HIV tests Households Human immunodeficiency virus Humans Hygiene Incidence Information systems Male Medical research Medical tests Medicine Medicine and Health Sciences Migration Patient satisfaction People and Places Planning Population Pregnancy Prevention Reproductive health Risk Factors Rural areas Rural Population Sexual Behavior Sexual Partners Sexually transmitted diseases Social aspects South Africa - epidemiology STD Teenage girls Teenagers Wellness programs Womens health Young Adult Young adults |
| title | Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T18%3A06%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Persistently%20high%20incidence%20of%20HIV%20and%20poor%20service%20uptake%20in%20adolescent%20girls%20and%20young%20women%20in%20rural%20KwaZulu-Natal,%20South%20Africa%20prior%20to%20DREAMS&rft.jtitle=PloS%20one&rft.au=Chimbindi,%20Natsayi&rft.date=2018-10-16&rft.volume=13&rft.issue=10&rft.spage=e0203193&rft.epage=e0203193&rft.pages=e0203193-e0203193&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0203193&rft_dat=%3Cgale_plos_%3EA559617723%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2120712110&rft_id=info:pmid/30325932&rft_galeid=A559617723&rft_doaj_id=oai_doaj_org_article_c7da71b1b15140169d42fa03b29d59a8&rfr_iscdi=true |