Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype

In patients with triple-negative breast cancer (TNBC), tumor-infiltrating lymphocytes (TILs) are associated with improved survival. Lehmann et al. identified 4 molecular subtypes of TNBC [basal-like (BL) 1, BL2, mesenchymal (M), and luminal androgen receptor (LAR)], and an immunomodulatory (IM) gene...

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Veröffentlicht in:	PloS one 2018-10, Vol.13 (10), p.e0204513-e0204513
Hauptverfasser:	Harano, Kenichi, Wang, Ying, Lim, Bora, Seitz, Robert S, Morris, Stephan W, Bailey, Daniel B, Hout, David R, Skelton, Rachel L, Ring, Brian Z, Masuda, Hiroko, Rao, Arvind U K, Laere, Steven Van, Bertucci, Francois, Woodward, Wendy A, Reuben, James M, Krishnamurthy, Savitri, Ueno, Naoto T
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Androgen receptors Androgens Bioinformatics Biology Biology and Life Sciences Biopsy Breast cancer Cancer Cancer therapies Cell cycle Cell survival Chemotherapy Consortia Gene expression Growth factors Health aspects Immune system Immunomodulation Infiltration Inflammation Life Sciences Lymphocytes Mastectomy Medical prognosis Medical research Medicine and Health Sciences Mesenchyme Metastases Oncology Patients Social Sciences Stem cells Tumor-infiltrating lymphocytes Tumors
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