Cholesterol-lowering effect of Lactobacillus rhamnosus BFE5264 and its influence on the gut microbiome and propionate level in a murine model

Thanks to recent scientific progress a relationship between the intestinal microbiota and metabolic diseases could be established. A deeper understanding of underlying mechanisms has opened ways towards new approaches for alleviating conditions associated with metabolic diseases. Dysbiosis appears t...

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Veröffentlicht in:	PloS one 2018-08, Vol.13 (8), p.e0203150-e0203150
Hauptverfasser:	Park, Soyoung, Kang, Jihee, Choi, Sanghaeng, Park, Haryung, Hwang, Eunchong, Kang, Youn-Goo, Kim, Ah-Ram, Holzapfel, Wilhelm, Ji, Yosep
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animal models Animals Bacteria Bile Biology and Life Sciences Biosynthesis Blood cholesterol Cholesterol Cholesterol - administration & dosage Cholesterol - metabolism Diabetes mellitus Diet, High-Fat - adverse effects Digestive system Digestive tract Disease Models, Animal Dysbacteriosis Energy Fatty acids Fatty Acids, Volatile - analysis Fatty Acids, Volatile - metabolism Feces - chemistry Feces - microbiology Fermented milk products Food Gastrointestinal Microbiome Gastrointestinal tract Gene expression Health aspects Health promotion High cholesterol diet Intestinal microflora Intestinal Mucosa - metabolism Intestinal Mucosa - microbiology Intestine Laboratory animals Lactic acid Lactic acid bacteria Lactobacillus Lactobacillus rhamnosus Life sciences Lipid metabolism Liver Liver - metabolism Male Medical research Medicine and Health Sciences Metabolic disorders Metabolic regulation Metabolic syndrome Metabolism Mice, Inbred C57BL Microbiomes Microbiota Microbiota (Symbiotic organisms) Nutrition research Physiological aspects Probiotics Probiotics - administration & dosage Propionates - metabolism Propionic acid RNA, Messenger Rodents
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