The current epidemiological status of urogenital schistosomiasis among primary school pupils in Katsina State, Nigeria: An imperative for a scale up of water and sanitation initiative and mass administration of medicines with Praziquantel
Human schistosomiasis, a debilitating and chronic disease, is among a set of 17 neglected tropical infectious diseases of poverty that is currently posing a threat to the wellbeing of 2 billion people in the world. The SHAWN/WASH and MAM programmes in the study area require epidemiological data to e...
Gespeichert in:
| Veröffentlicht in: | PLoS neglected tropical diseases 2018-07, Vol.12 (7), p.e0006636 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 7 |
| container_start_page | e0006636 |
| container_title | PLoS neglected tropical diseases |
| container_volume | 12 |
| creator | Atalabi, Tolulope Ebenezer Adoh, Stephen Dumebi Eze, Kingsley Marvin |
| description | Human schistosomiasis, a debilitating and chronic disease, is among a set of 17 neglected tropical infectious diseases of poverty that is currently posing a threat to the wellbeing of 2 billion people in the world. The SHAWN/WASH and MAM programmes in the study area require epidemiological data to enhance their effectiveness. We therefore embarked on this cross-sectional study with the aim of investigating the prevalence, intensity and risk factors of urogenital schistosomiasis.
Interviewed 484 respondents produced terminal urine samples (between 10.00h - 14.00h) which were analyzed with Medi ─Test Combi 10 and centrifuged at 400 r.p.m for 4 minutes using C2 series Centurion Scientific Centrifuge. Eggs of S. haematobium were identified with their terminal spines using Motic Binocular Microscope. Data were analyzed with Epi Info 7. In this study, the overall prevalence and arithmetic mean intensity of the infection were 8.68% (6.39─ 11.64) and 80.09 (30.92─129.28) eggs per 10ml of urine respectively. Urogenital schistosomiasis was significantly associated with knowledge about the snail host (χ2 = 4.23; P = 0.0398); water contact activities (χ2 = 25.788; P = 0.0001), gender (χ2 = 16.722; P = 0.0001); age (χ2 = 9.589; P = 0.0019); economic status of school attended (χ2 = 4.869; P = 0.0273); residence distance from open water sources (χ2 = 10.546; P = 0.0012); mothers' occupational (χ2 = 6.081; P = 0.0137) and educational status (χ2 = 4.139; P = 0.0419).
The overall prevalence obtained in this survey shows that the study area was at a low-risk degree of endemicity for urogenital schistosomiasis. Beneath this is a subtle, latent and deadly morbidity-inducing heavy mean intensity of infection, calling for urgent implementation of WHO recommendation that MAM with PZQ be carried out twice for School-Age Children (enrolled or not enrolled) during their primary schooling age (once each at the point of admission and graduation). The criteria for classifying endemic areas for schistosomiasis should also be reviewed to capture the magnitude of mean intensity of infection rather than prevalence only as this may underplay its epidemiological severity. |
| doi_str_mv | 10.1371/journal.pntd.0006636 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2089341449</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A548630003</galeid><doaj_id>oai_doaj_org_article_e5d6a2185e4d4580a7893f1a8dd1f223</doaj_id><sourcerecordid>A548630003</sourcerecordid><originalsourceid>FETCH-LOGICAL-c624t-d43759b7e85cc28834f19b57633ea6ed91c651ae9d2a3c54e41b98c0cb6e12503</originalsourceid><addsrcrecordid>eNp1U9tu1DAQjRCIlsIfILCExBO7xHGcSx-QqopLRQVIlGdr1plkp0rs1HZawUfzDThsWnUlkB9snTnnzNjjSZLnPF1zUfK3l3ZyBvr1aEKzTtO0KETxIDnktZCrrBTy4b3zQfLE-8s0lbWs-OPkIKvrsi6q_DD5fbFFpifn0ASGIzU4kO1tRxp65gOEyTPbssnZDg2FGdRb8sF6OxB48gwGazo2OhrA_Zyj1vZsnEbqPSPDPkPwZIB9j174hn2hDh3BMTsxjIYRHQS6RtZaxyCKoUc2jXPGm0iPmGmYhzlxIBsV8UQ7xRwZwMf8zRBhH9yOEqUDNqTJoGc3FLbsm4NfdDWBCdg_TR610Ht8tuxHyY8P7y9OP63Ov348Oz05X-kiy8OqyUUp602JldQ6qyqRt7zeyLIQAqHApua6kBywbjIQWuaY801d6VRvCuSZTMVR8nLnO_bWq6VVXmVpVYuc53kdGWc7RmPhUi3PpyyQ-gtY1ylwgXSPCmVTQMYriXmTyyqFMrq0HKqm4W2Wiej1bsk2beLldeylg37PdD9iaKs6e62KVPKinMt9tRg4ezWhD_8peWF1sU2KTGujmR7Ia3Ui86oQ8RfOxaz_wYpr_lraGmwp4nuC1_cEW4Q-bL3tp7mdfp-Y74jaWe8dtnc35KmaZ-K2ajXPhFpmIspe3H-dO9HtEIg_QlcPvA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2089341449</pqid></control><display><type>article</type><title>The current epidemiological status of urogenital schistosomiasis among primary school pupils in Katsina State, Nigeria: An imperative for a scale up of water and sanitation initiative and mass administration of medicines with Praziquantel</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>Public Library of Science (PLoS)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Atalabi, Tolulope Ebenezer ; Adoh, Stephen Dumebi ; Eze, Kingsley Marvin</creator><contributor>Gray, Darren J.</contributor><creatorcontrib>Atalabi, Tolulope Ebenezer ; Adoh, Stephen Dumebi ; Eze, Kingsley Marvin ; Gray, Darren J.</creatorcontrib><description>Human schistosomiasis, a debilitating and chronic disease, is among a set of 17 neglected tropical infectious diseases of poverty that is currently posing a threat to the wellbeing of 2 billion people in the world. The SHAWN/WASH and MAM programmes in the study area require epidemiological data to enhance their effectiveness. We therefore embarked on this cross-sectional study with the aim of investigating the prevalence, intensity and risk factors of urogenital schistosomiasis.
Interviewed 484 respondents produced terminal urine samples (between 10.00h - 14.00h) which were analyzed with Medi ─Test Combi 10 and centrifuged at 400 r.p.m for 4 minutes using C2 series Centurion Scientific Centrifuge. Eggs of S. haematobium were identified with their terminal spines using Motic Binocular Microscope. Data were analyzed with Epi Info 7. In this study, the overall prevalence and arithmetic mean intensity of the infection were 8.68% (6.39─ 11.64) and 80.09 (30.92─129.28) eggs per 10ml of urine respectively. Urogenital schistosomiasis was significantly associated with knowledge about the snail host (χ2 = 4.23; P = 0.0398); water contact activities (χ2 = 25.788; P = 0.0001), gender (χ2 = 16.722; P = 0.0001); age (χ2 = 9.589; P = 0.0019); economic status of school attended (χ2 = 4.869; P = 0.0273); residence distance from open water sources (χ2 = 10.546; P = 0.0012); mothers' occupational (χ2 = 6.081; P = 0.0137) and educational status (χ2 = 4.139; P = 0.0419).
The overall prevalence obtained in this survey shows that the study area was at a low-risk degree of endemicity for urogenital schistosomiasis. Beneath this is a subtle, latent and deadly morbidity-inducing heavy mean intensity of infection, calling for urgent implementation of WHO recommendation that MAM with PZQ be carried out twice for School-Age Children (enrolled or not enrolled) during their primary schooling age (once each at the point of admission and graduation). The criteria for classifying endemic areas for schistosomiasis should also be reviewed to capture the magnitude of mean intensity of infection rather than prevalence only as this may underplay its epidemiological severity.</description><identifier>ISSN: 1935-2735</identifier><identifier>ISSN: 1935-2727</identifier><identifier>EISSN: 1935-2735</identifier><identifier>DOI: 10.1371/journal.pntd.0006636</identifier><identifier>PMID: 29979684</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adolescent ; Age ; Analysis ; Animals ; Anthelmintics - administration & dosage ; Attitude to Health ; Biology and Life Sciences ; Centrifuges ; Child ; Child, Preschool ; Children ; Cross-Sectional Studies ; Data processing ; Eggs ; Elementary school students ; Endemism ; Epidemiology ; Female ; Funding ; Gender ; Health aspects ; Humans ; Infections ; Infectious diseases ; Knowledge ; Local government ; Male ; Mass Drug Administration ; Mathematics ; Medicine and Health Sciences ; Morbidity ; Nigeria - epidemiology ; People and Places ; Poverty ; Praziquantel ; Praziquantel - administration & dosage ; Prevalence ; Programmes ; Risk analysis ; Risk factors ; Sample size ; Sanitation ; Schistosoma haematobium - drug effects ; Schistosoma haematobium - isolation & purification ; Schistosoma haematobium - physiology ; Schistosomiasis ; Schistosomiasis haematobia - drug therapy ; Schistosomiasis haematobia - epidemiology ; Schistosomiasis haematobia - parasitology ; Schistosomiasis haematobia - psychology ; Secondary school students ; Secondary schools ; Social Sciences ; Students - psychology ; Students - statistics & numerical data ; Surveying ; Tropical climate ; Tropical diseases ; Urine ; Water - parasitology ; Water resource management</subject><ispartof>PLoS neglected tropical diseases, 2018-07, Vol.12 (7), p.e0006636</ispartof><rights>COPYRIGHT 2018 Public Library of Science</rights><rights>2018 Atalabi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2018 Atalabi et al 2018 Atalabi et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c624t-d43759b7e85cc28834f19b57633ea6ed91c651ae9d2a3c54e41b98c0cb6e12503</citedby><cites>FETCH-LOGICAL-c624t-d43759b7e85cc28834f19b57633ea6ed91c651ae9d2a3c54e41b98c0cb6e12503</cites><orcidid>0000-0002-4957-6970</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051670/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051670/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2929,23871,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29979684$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Gray, Darren J.</contributor><creatorcontrib>Atalabi, Tolulope Ebenezer</creatorcontrib><creatorcontrib>Adoh, Stephen Dumebi</creatorcontrib><creatorcontrib>Eze, Kingsley Marvin</creatorcontrib><title>The current epidemiological status of urogenital schistosomiasis among primary school pupils in Katsina State, Nigeria: An imperative for a scale up of water and sanitation initiative and mass administration of medicines with Praziquantel</title><title>PLoS neglected tropical diseases</title><addtitle>PLoS Negl Trop Dis</addtitle><description>Human schistosomiasis, a debilitating and chronic disease, is among a set of 17 neglected tropical infectious diseases of poverty that is currently posing a threat to the wellbeing of 2 billion people in the world. The SHAWN/WASH and MAM programmes in the study area require epidemiological data to enhance their effectiveness. We therefore embarked on this cross-sectional study with the aim of investigating the prevalence, intensity and risk factors of urogenital schistosomiasis.
Interviewed 484 respondents produced terminal urine samples (between 10.00h - 14.00h) which were analyzed with Medi ─Test Combi 10 and centrifuged at 400 r.p.m for 4 minutes using C2 series Centurion Scientific Centrifuge. Eggs of S. haematobium were identified with their terminal spines using Motic Binocular Microscope. Data were analyzed with Epi Info 7. In this study, the overall prevalence and arithmetic mean intensity of the infection were 8.68% (6.39─ 11.64) and 80.09 (30.92─129.28) eggs per 10ml of urine respectively. Urogenital schistosomiasis was significantly associated with knowledge about the snail host (χ2 = 4.23; P = 0.0398); water contact activities (χ2 = 25.788; P = 0.0001), gender (χ2 = 16.722; P = 0.0001); age (χ2 = 9.589; P = 0.0019); economic status of school attended (χ2 = 4.869; P = 0.0273); residence distance from open water sources (χ2 = 10.546; P = 0.0012); mothers' occupational (χ2 = 6.081; P = 0.0137) and educational status (χ2 = 4.139; P = 0.0419).
The overall prevalence obtained in this survey shows that the study area was at a low-risk degree of endemicity for urogenital schistosomiasis. Beneath this is a subtle, latent and deadly morbidity-inducing heavy mean intensity of infection, calling for urgent implementation of WHO recommendation that MAM with PZQ be carried out twice for School-Age Children (enrolled or not enrolled) during their primary schooling age (once each at the point of admission and graduation). The criteria for classifying endemic areas for schistosomiasis should also be reviewed to capture the magnitude of mean intensity of infection rather than prevalence only as this may underplay its epidemiological severity.</description><subject>Adolescent</subject><subject>Age</subject><subject>Analysis</subject><subject>Animals</subject><subject>Anthelmintics - administration & dosage</subject><subject>Attitude to Health</subject><subject>Biology and Life Sciences</subject><subject>Centrifuges</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Cross-Sectional Studies</subject><subject>Data processing</subject><subject>Eggs</subject><subject>Elementary school students</subject><subject>Endemism</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Funding</subject><subject>Gender</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Knowledge</subject><subject>Local government</subject><subject>Male</subject><subject>Mass Drug Administration</subject><subject>Mathematics</subject><subject>Medicine and Health Sciences</subject><subject>Morbidity</subject><subject>Nigeria - epidemiology</subject><subject>People and Places</subject><subject>Poverty</subject><subject>Praziquantel</subject><subject>Praziquantel - administration & dosage</subject><subject>Prevalence</subject><subject>Programmes</subject><subject>Risk analysis</subject><subject>Risk factors</subject><subject>Sample size</subject><subject>Sanitation</subject><subject>Schistosoma haematobium - drug effects</subject><subject>Schistosoma haematobium - isolation & purification</subject><subject>Schistosoma haematobium - physiology</subject><subject>Schistosomiasis</subject><subject>Schistosomiasis haematobia - drug therapy</subject><subject>Schistosomiasis haematobia - epidemiology</subject><subject>Schistosomiasis haematobia - parasitology</subject><subject>Schistosomiasis haematobia - psychology</subject><subject>Secondary school students</subject><subject>Secondary schools</subject><subject>Social Sciences</subject><subject>Students - psychology</subject><subject>Students - statistics & numerical data</subject><subject>Surveying</subject><subject>Tropical climate</subject><subject>Tropical diseases</subject><subject>Urine</subject><subject>Water - parasitology</subject><subject>Water resource management</subject><issn>1935-2735</issn><issn>1935-2727</issn><issn>1935-2735</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNp1U9tu1DAQjRCIlsIfILCExBO7xHGcSx-QqopLRQVIlGdr1plkp0rs1HZawUfzDThsWnUlkB9snTnnzNjjSZLnPF1zUfK3l3ZyBvr1aEKzTtO0KETxIDnktZCrrBTy4b3zQfLE-8s0lbWs-OPkIKvrsi6q_DD5fbFFpifn0ASGIzU4kO1tRxp65gOEyTPbssnZDg2FGdRb8sF6OxB48gwGazo2OhrA_Zyj1vZsnEbqPSPDPkPwZIB9j174hn2hDh3BMTsxjIYRHQS6RtZaxyCKoUc2jXPGm0iPmGmYhzlxIBsV8UQ7xRwZwMf8zRBhH9yOEqUDNqTJoGc3FLbsm4NfdDWBCdg_TR610Ht8tuxHyY8P7y9OP63Ov348Oz05X-kiy8OqyUUp602JldQ6qyqRt7zeyLIQAqHApua6kBywbjIQWuaY801d6VRvCuSZTMVR8nLnO_bWq6VVXmVpVYuc53kdGWc7RmPhUi3PpyyQ-gtY1ylwgXSPCmVTQMYriXmTyyqFMrq0HKqm4W2Wiej1bsk2beLldeylg37PdD9iaKs6e62KVPKinMt9tRg4ezWhD_8peWF1sU2KTGujmR7Ia3Ui86oQ8RfOxaz_wYpr_lraGmwp4nuC1_cEW4Q-bL3tp7mdfp-Y74jaWe8dtnc35KmaZ-K2ajXPhFpmIspe3H-dO9HtEIg_QlcPvA</recordid><startdate>20180706</startdate><enddate>20180706</enddate><creator>Atalabi, Tolulope Ebenezer</creator><creator>Adoh, Stephen Dumebi</creator><creator>Eze, Kingsley Marvin</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7SS</scope><scope>7T2</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>H95</scope><scope>H97</scope><scope>K9.</scope><scope>L.G</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-4957-6970</orcidid></search><sort><creationdate>20180706</creationdate><title>The current epidemiological status of urogenital schistosomiasis among primary school pupils in Katsina State, Nigeria: An imperative for a scale up of water and sanitation initiative and mass administration of medicines with Praziquantel</title><author>Atalabi, Tolulope Ebenezer ; Adoh, Stephen Dumebi ; Eze, Kingsley Marvin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c624t-d43759b7e85cc28834f19b57633ea6ed91c651ae9d2a3c54e41b98c0cb6e12503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Age</topic><topic>Analysis</topic><topic>Animals</topic><topic>Anthelmintics - administration & dosage</topic><topic>Attitude to Health</topic><topic>Biology and Life Sciences</topic><topic>Centrifuges</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Cross-Sectional Studies</topic><topic>Data processing</topic><topic>Eggs</topic><topic>Elementary school students</topic><topic>Endemism</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Funding</topic><topic>Gender</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Knowledge</topic><topic>Local government</topic><topic>Male</topic><topic>Mass Drug Administration</topic><topic>Mathematics</topic><topic>Medicine and Health Sciences</topic><topic>Morbidity</topic><topic>Nigeria - epidemiology</topic><topic>People and Places</topic><topic>Poverty</topic><topic>Praziquantel</topic><topic>Praziquantel - administration & dosage</topic><topic>Prevalence</topic><topic>Programmes</topic><topic>Risk analysis</topic><topic>Risk factors</topic><topic>Sample size</topic><topic>Sanitation</topic><topic>Schistosoma haematobium - drug effects</topic><topic>Schistosoma haematobium - isolation & purification</topic><topic>Schistosoma haematobium - physiology</topic><topic>Schistosomiasis</topic><topic>Schistosomiasis haematobia - drug therapy</topic><topic>Schistosomiasis haematobia - epidemiology</topic><topic>Schistosomiasis haematobia - parasitology</topic><topic>Schistosomiasis haematobia - psychology</topic><topic>Secondary school students</topic><topic>Secondary schools</topic><topic>Social Sciences</topic><topic>Students - psychology</topic><topic>Students - statistics & numerical data</topic><topic>Surveying</topic><topic>Tropical climate</topic><topic>Tropical diseases</topic><topic>Urine</topic><topic>Water - parasitology</topic><topic>Water resource management</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Atalabi, Tolulope Ebenezer</creatorcontrib><creatorcontrib>Adoh, Stephen Dumebi</creatorcontrib><creatorcontrib>Eze, Kingsley Marvin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PLoS neglected tropical diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Atalabi, Tolulope Ebenezer</au><au>Adoh, Stephen Dumebi</au><au>Eze, Kingsley Marvin</au><au>Gray, Darren J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The current epidemiological status of urogenital schistosomiasis among primary school pupils in Katsina State, Nigeria: An imperative for a scale up of water and sanitation initiative and mass administration of medicines with Praziquantel</atitle><jtitle>PLoS neglected tropical diseases</jtitle><addtitle>PLoS Negl Trop Dis</addtitle><date>2018-07-06</date><risdate>2018</risdate><volume>12</volume><issue>7</issue><spage>e0006636</spage><pages>e0006636-</pages><issn>1935-2735</issn><issn>1935-2727</issn><eissn>1935-2735</eissn><abstract>Human schistosomiasis, a debilitating and chronic disease, is among a set of 17 neglected tropical infectious diseases of poverty that is currently posing a threat to the wellbeing of 2 billion people in the world. The SHAWN/WASH and MAM programmes in the study area require epidemiological data to enhance their effectiveness. We therefore embarked on this cross-sectional study with the aim of investigating the prevalence, intensity and risk factors of urogenital schistosomiasis.
Interviewed 484 respondents produced terminal urine samples (between 10.00h - 14.00h) which were analyzed with Medi ─Test Combi 10 and centrifuged at 400 r.p.m for 4 minutes using C2 series Centurion Scientific Centrifuge. Eggs of S. haematobium were identified with their terminal spines using Motic Binocular Microscope. Data were analyzed with Epi Info 7. In this study, the overall prevalence and arithmetic mean intensity of the infection were 8.68% (6.39─ 11.64) and 80.09 (30.92─129.28) eggs per 10ml of urine respectively. Urogenital schistosomiasis was significantly associated with knowledge about the snail host (χ2 = 4.23; P = 0.0398); water contact activities (χ2 = 25.788; P = 0.0001), gender (χ2 = 16.722; P = 0.0001); age (χ2 = 9.589; P = 0.0019); economic status of school attended (χ2 = 4.869; P = 0.0273); residence distance from open water sources (χ2 = 10.546; P = 0.0012); mothers' occupational (χ2 = 6.081; P = 0.0137) and educational status (χ2 = 4.139; P = 0.0419).
The overall prevalence obtained in this survey shows that the study area was at a low-risk degree of endemicity for urogenital schistosomiasis. Beneath this is a subtle, latent and deadly morbidity-inducing heavy mean intensity of infection, calling for urgent implementation of WHO recommendation that MAM with PZQ be carried out twice for School-Age Children (enrolled or not enrolled) during their primary schooling age (once each at the point of admission and graduation). The criteria for classifying endemic areas for schistosomiasis should also be reviewed to capture the magnitude of mean intensity of infection rather than prevalence only as this may underplay its epidemiological severity.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>29979684</pmid><doi>10.1371/journal.pntd.0006636</doi><orcidid>https://orcid.org/0000-0002-4957-6970</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1935-2735 |
| ispartof | PLoS neglected tropical diseases, 2018-07, Vol.12 (7), p.e0006636 |
| issn | 1935-2735 1935-2727 1935-2735 |
| language | eng |
| recordid | cdi_plos_journals_2089341449 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central Open Access; Public Library of Science (PLoS); EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adolescent Age Analysis Animals Anthelmintics - administration & dosage Attitude to Health Biology and Life Sciences Centrifuges Child Child, Preschool Children Cross-Sectional Studies Data processing Eggs Elementary school students Endemism Epidemiology Female Funding Gender Health aspects Humans Infections Infectious diseases Knowledge Local government Male Mass Drug Administration Mathematics Medicine and Health Sciences Morbidity Nigeria - epidemiology People and Places Poverty Praziquantel Praziquantel - administration & dosage Prevalence Programmes Risk analysis Risk factors Sample size Sanitation Schistosoma haematobium - drug effects Schistosoma haematobium - isolation & purification Schistosoma haematobium - physiology Schistosomiasis Schistosomiasis haematobia - drug therapy Schistosomiasis haematobia - epidemiology Schistosomiasis haematobia - parasitology Schistosomiasis haematobia - psychology Secondary school students Secondary schools Social Sciences Students - psychology Students - statistics & numerical data Surveying Tropical climate Tropical diseases Urine Water - parasitology Water resource management |
| title | The current epidemiological status of urogenital schistosomiasis among primary school pupils in Katsina State, Nigeria: An imperative for a scale up of water and sanitation initiative and mass administration of medicines with Praziquantel |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T10%3A02%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20current%20epidemiological%20status%20of%20urogenital%20schistosomiasis%20among%20primary%20school%20pupils%20in%20Katsina%20State,%20Nigeria:%20An%20imperative%20for%20a%20scale%20up%20of%20water%20and%20sanitation%20initiative%20and%20mass%20administration%20of%20medicines%20with%20Praziquantel&rft.jtitle=PLoS%20neglected%20tropical%20diseases&rft.au=Atalabi,%20Tolulope%20Ebenezer&rft.date=2018-07-06&rft.volume=12&rft.issue=7&rft.spage=e0006636&rft.pages=e0006636-&rft.issn=1935-2735&rft.eissn=1935-2735&rft_id=info:doi/10.1371/journal.pntd.0006636&rft_dat=%3Cgale_plos_%3EA548630003%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2089341449&rft_id=info:pmid/29979684&rft_galeid=A548630003&rft_doaj_id=oai_doaj_org_article_e5d6a2185e4d4580a7893f1a8dd1f223&rfr_iscdi=true |