Effects of color lenses on visual evoked magnetic fields following bright light
Photophobia is a common condition in which bright light causes an unpleasant feeling due to increased sensitivity to light. In addition to discomfort, photophobia may be accompanied by visual dysfunction. The present study was conducted in order to examine whether visual evoked cortical responses co...
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| creator | Suzuki, Masaya Kumagai, Naoya Inui, Koji Kakigi, Ryusuke |
| description | Photophobia is a common condition in which bright light causes an unpleasant feeling due to increased sensitivity to light. In addition to discomfort, photophobia may be accompanied by visual dysfunction. The present study was conducted in order to examine whether visual evoked cortical responses contribute to the assessment of visual dysfunction due to bright light. Visual evoked magnetic fields (VEFs) following the presentation of a uniform bright light of 200-3700 cd/m2 in the lower visual field were recorded in 10 healthy volunteers and the effects of five color lenses: yellow, blue, gray, green, and colorless, were examined. VEFs were subjected to a multi-dipole analysis that resulted in the separation of several source activities, including the retina, V1, V2, V6, and fusiform gyrus. Source activity in the retina corresponding to the ERG b-wave exhibited a reduced amplitude and elongated peak latency with the yellow lens. Its latency strongly correlated with transmittance at 450 nm. On the other hand, cortical activities in V1 and the fusiform gyrus were stronger with the yellow lens than with the other color and colorless lenses. Only blue-light blocking showed significant effects. The result showing that the yellow lens enhanced V1 and fusiform activities indicated that processing in these areas was improved when subjects used this lens. The combination of delayed retinal activity and increased visual cortex activity may be an objective indicator of the effects of a color lens on visual function. |
| doi_str_mv | 10.1371/journal.pone.0201804 |
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In addition to discomfort, photophobia may be accompanied by visual dysfunction. The present study was conducted in order to examine whether visual evoked cortical responses contribute to the assessment of visual dysfunction due to bright light. Visual evoked magnetic fields (VEFs) following the presentation of a uniform bright light of 200-3700 cd/m2 in the lower visual field were recorded in 10 healthy volunteers and the effects of five color lenses: yellow, blue, gray, green, and colorless, were examined. VEFs were subjected to a multi-dipole analysis that resulted in the separation of several source activities, including the retina, V1, V2, V6, and fusiform gyrus. Source activity in the retina corresponding to the ERG b-wave exhibited a reduced amplitude and elongated peak latency with the yellow lens. Its latency strongly correlated with transmittance at 450 nm. On the other hand, cortical activities in V1 and the fusiform gyrus were stronger with the yellow lens than with the other color and colorless lenses. Only blue-light blocking showed significant effects. The result showing that the yellow lens enhanced V1 and fusiform activities indicated that processing in these areas was improved when subjects used this lens. The combination of delayed retinal activity and increased visual cortex activity may be an objective indicator of the effects of a color lens on visual function.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0201804</identifier><identifier>PMID: 30071095</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Analysis ; Biology and Life Sciences ; Care and treatment ; Color ; Color vision ; Contact lenses ; Electroretinograms ; Elongation ; Latency ; Light ; Magnetic fields ; Magnetic lenses ; Medicine and Health Sciences ; Migraine ; Pain ; Physical Sciences ; Physiology ; Research and Analysis Methods ; Retina ; Social Sciences ; Vision disorders ; Visual cortex ; Visual field ; Visual fields ; Visual perception</subject><ispartof>PloS one, 2018-08, Vol.13 (8), p.e0201804-e0201804</ispartof><rights>COPYRIGHT 2018 Public Library of Science</rights><rights>2018 Suzuki et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 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In addition to discomfort, photophobia may be accompanied by visual dysfunction. The present study was conducted in order to examine whether visual evoked cortical responses contribute to the assessment of visual dysfunction due to bright light. Visual evoked magnetic fields (VEFs) following the presentation of a uniform bright light of 200-3700 cd/m2 in the lower visual field were recorded in 10 healthy volunteers and the effects of five color lenses: yellow, blue, gray, green, and colorless, were examined. VEFs were subjected to a multi-dipole analysis that resulted in the separation of several source activities, including the retina, V1, V2, V6, and fusiform gyrus. Source activity in the retina corresponding to the ERG b-wave exhibited a reduced amplitude and elongated peak latency with the yellow lens. Its latency strongly correlated with transmittance at 450 nm. On the other hand, cortical activities in V1 and the fusiform gyrus were stronger with the yellow lens than with the other color and colorless lenses. Only blue-light blocking showed significant effects. The result showing that the yellow lens enhanced V1 and fusiform activities indicated that processing in these areas was improved when subjects used this lens. The combination of delayed retinal activity and increased visual cortex activity may be an objective indicator of the effects of a color lens on visual function.</description><subject>Analysis</subject><subject>Biology and Life Sciences</subject><subject>Care and treatment</subject><subject>Color</subject><subject>Color vision</subject><subject>Contact lenses</subject><subject>Electroretinograms</subject><subject>Elongation</subject><subject>Latency</subject><subject>Light</subject><subject>Magnetic fields</subject><subject>Magnetic lenses</subject><subject>Medicine and Health Sciences</subject><subject>Migraine</subject><subject>Pain</subject><subject>Physical Sciences</subject><subject>Physiology</subject><subject>Research and Analysis Methods</subject><subject>Retina</subject><subject>Social Sciences</subject><subject>Vision disorders</subject><subject>Visual cortex</subject><subject>Visual field</subject><subject>Visual fields</subject><subject>Visual 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Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Suzuki, Masaya</au><au>Kumagai, Naoya</au><au>Inui, Koji</au><au>Kakigi, Ryusuke</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of color lenses on visual evoked magnetic fields following bright light</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2018-08-02</date><risdate>2018</risdate><volume>13</volume><issue>8</issue><spage>e0201804</spage><epage>e0201804</epage><pages>e0201804-e0201804</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Photophobia is a common condition in which bright light causes an unpleasant feeling due to increased sensitivity to light. In addition to discomfort, photophobia may be accompanied by visual dysfunction. The present study was conducted in order to examine whether visual evoked cortical responses contribute to the assessment of visual dysfunction due to bright light. Visual evoked magnetic fields (VEFs) following the presentation of a uniform bright light of 200-3700 cd/m2 in the lower visual field were recorded in 10 healthy volunteers and the effects of five color lenses: yellow, blue, gray, green, and colorless, were examined. VEFs were subjected to a multi-dipole analysis that resulted in the separation of several source activities, including the retina, V1, V2, V6, and fusiform gyrus. Source activity in the retina corresponding to the ERG b-wave exhibited a reduced amplitude and elongated peak latency with the yellow lens. Its latency strongly correlated with transmittance at 450 nm. On the other hand, cortical activities in V1 and the fusiform gyrus were stronger with the yellow lens than with the other color and colorless lenses. Only blue-light blocking showed significant effects. The result showing that the yellow lens enhanced V1 and fusiform activities indicated that processing in these areas was improved when subjects used this lens. The combination of delayed retinal activity and increased visual cortex activity may be an objective indicator of the effects of a color lens on visual function.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>30071095</pmid><doi>10.1371/journal.pone.0201804</doi><tpages>e0201804</tpages><orcidid>https://orcid.org/0000-0001-5867-9990</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Analysis Biology and Life Sciences Care and treatment Color Color vision Contact lenses Electroretinograms Elongation Latency Light Magnetic fields Magnetic lenses Medicine and Health Sciences Migraine Pain Physical Sciences Physiology Research and Analysis Methods Retina Social Sciences Vision disorders Visual cortex Visual field Visual fields Visual perception |
| title | Effects of color lenses on visual evoked magnetic fields following bright light |
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