Rv1460, a SufR homologue, is a repressor of the suf operon in Mycobacterium tuberculosis

Iron-sulphur (Fe-S) clusters are ubiquitous co-factors which require multi-protein systems for their synthesis. In Mycobacterium tuberculosis, the Rv1460-Rv1461-Rv1462-Rv1463-csd-Rv1465-Rv1466 operon (suf operon) encodes the primary Fe-S cluster biogenesis system. The first gene in this operon, Rv14...

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Veröffentlicht in:	PloS one 2018-07, Vol.13 (7), p.e0200145-e0200145
Hauptverfasser:	Willemse, Danicke, Weber, Brandon, Masino, Laura, Warren, Robin M, Adinolfi, Salvatore, Pastore, Annalisa, Williams, Monique J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacteria Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Binding Sites - genetics Biology and Life Sciences Biosynthesis Chromosomes Circular dichroism Clusters Conserved Sequence Councils Cyanobacteria - genetics Cyanobacteria - metabolism Cysteine Deoxyribonucleic acid Dichroism DNA E coli Enzymes Escherichia coli Gene Deletion Gene expression Genes, Bacterial Genomes Gram-positive bacteria Health sciences Homology Humans Infections Iron Iron-Sulfur Proteins - chemistry Iron-Sulfur Proteins - genetics Iron-Sulfur Proteins - metabolism Medical research Metabolism Molecular biology Mutants Mutation Mycobacterium tuberculosis Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - growth & development Mycobacterium tuberculosis - metabolism Operon Oxidative stress Physical Sciences Promoter Regions, Genetic Protein biosynthesis Proteins Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism Repressor Proteins - chemistry Repressor Proteins - genetics Repressor Proteins - metabolism Spectroscopy Sulfur Supervision Transcription Tuberculosis
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