Unfocused shockwaves for osteoinduction in bone substitutes in rat cortical bone defects

Bone substitutes are frequently used in clinical practice but often exhibit limited osteoinductivity. We hypothesized that unfocused shockwaves enhance the osteoinductivity of bone substitutes and improve osteointegration and angiogenesis. Three different bone substitutes, namely porous tricalcium p...

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Veröffentlicht in:	PloS one 2018-07, Vol.13 (7), p.e0200020-e0200020
Hauptverfasser:	Koolen, Marianne K E, Pouran, Behdad, Öner, Fetullah C, Zadpoor, Amir A, van der Jagt, Olav P, Weinans, Harrie
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Biocompatibility Biological properties Biology and Life Sciences Biomechanics Biomedical materials Bone (cortical) Bone biomaterials Bone resorption Calcium phosphates CAT scans Computed tomography Cortical bone Defects Engineering Femur Histology Hydroxyapatite Lithotripsy Medicine and Health Sciences Neovascularization Osseointegration Osteointegration Physical Sciences Protective coatings Rats Research and Analysis Methods Rodents Shock waves Substitute bone Surgery Surgical implants Titanium Titanium alloys Titanium base alloys Tricalcium phosphate Wound healing
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