Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial

Group A streptococcus (GAS) is a serious human pathogen that affects people of different ages and socio-economic levels. Although vaccination is potentially one of the most effective methods to control GAS infection and its sequelae, few prototype vaccines have been investigated in humans. In this s...

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Veröffentlicht in:	PloS one 2018-07, Vol.13 (7), p.e0198658
Hauptverfasser:	Sekuloski, Silvana, Batzloff, Michael R, Griffin, Paul, Parsonage, William, Elliott, Suzanne, Hartas, Jon, O'Rourke, Peter, Marquart, Louise, Pandey, Manisha, Rubin, Fran A, Carapetis, Jonathan, McCarthy, James, Good, Michael F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Aluminum Antibodies Biology and Life Sciences Cardiovascular disease Clinical trials Complications Conjugate vaccines Control methods Developing countries Drug delivery systems Immunization Immunogenicity Immunoglobulins Infections Infectious diseases Laboratories LDCs McCarthy, James Medical research Medicine Medicine and Health Sciences Patient outcomes Peptides Prevention Proteins Research and Analysis Methods Safety Streptococcal infections Streptococcus Streptococcus infections Supervision Vaccines
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