APRI and FIB-4 in the evaluation of liver fibrosis in chronic hepatitis C patients stratified by AST level

The aspartate aminotransferase (AST)-to-platelet ratio index (APRI) and fibrosis-4 index (FIB-4) are commonly used compound surrogates for advanced fibrosis in chronic hepatitis C (CHC) patients. However, the use of APRI and FIB-4 entails a risk of overestimating the fibrosis stage due to the impact...

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Veröffentlicht in:	PloS one 2018-06, Vol.13 (6), p.e0199760-e0199760
Hauptverfasser:	Yen, Yi-Hao, Kuo, Fang-Ying, Kee, Kwong-Ming, Chang, Kuo-Chin, Tsai, Ming-Chao, Hu, Tsung-Hui, Lu, Sheng-Nan, Wang, Jing-Houng, Hung, Chao-Hung, Chen, Chien-Hung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aspartate aminotransferase Aspartate Aminotransferases - blood Biology and Life Sciences Biopsy Blood Platelets - metabolism Blood Platelets - pathology Care and treatment Cirrhosis Complications and side effects Development and progression Feasibility studies Female Fibrosis Gene expression Genetic aspects Health aspects Hepatitis Hepatitis C Hepatitis C, Chronic - blood Hepatitis C, Chronic - complications Hepatitis C, Chronic - pathology Hepatology Histology Hospitals Humans Infections Interferon Internal medicine Laboratories Liver Liver cirrhosis Liver Cirrhosis - blood Liver Cirrhosis - etiology Liver Cirrhosis - pathology Liver diseases Male Medical diagnosis Medicine Medicine and Health Sciences Middle Aged Obesity Patients Platelet Count Predictive Value of Tests Retrospective Studies Systematic review Transaminases
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